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Database evaluation of paracetamol concentrations in a toxicology laboratory in Toruń, Poland, 2018–2022 Cover

Database evaluation of paracetamol concentrations in a toxicology laboratory in Toruń, Poland, 2018–2022

Open Access
|Feb 2025

Abstract

Paracetamol is a commonly used and easily accessible drug with antipyretic and analgesic properties. Its overdose leads to severe liver failure. In diagnostic procedures, an important role is played by the determination of paracetamol concentration in blood serum, which not only confirms poisoning but also helps assess the risk of hepatotoxicity. The aim of this study was to retrospectively analyze the data on paracetamol concentration tests performed at the Toxicology Laboratory of the Ludwik Rydygier Provincial Polyclinic Hospital in Toruń between 2018–2022. The serum of patients suspected of poisoning was tested using the immunoassay method. The study demonstrated an upward trend in the number of paracetamol concentration tests performed. It was observed that the highest percentage of patients were female, and the largest age group ranged 3–17 years old. The positive paracetamol concentrations most often fell within toxic levels and were most frequently obtained from female patients.

DOI: https://doi.org/10.21164/pomjlifesci.1034 | Journal eISSN: 2719-6313 | Journal ISSN: 2450-4637
Language: English
Page range: 64 - 69
Published on: Feb 21, 2025
Published by: Pomeranian Medical University
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Aleksandra Maria Meger, Urszula Korbal, Joanna Ledwolorz, Agnieszka Ewa Szymańska, Paweł Tomasz Korbal, published by Pomeranian Medical University
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.