
Characteristics of participants
| VARIABLE | PROPHYLAXIS MEAN (±SD) | ON-DEMAND MEAN (±SD) |
|---|---|---|
| Age at enrolment (years) | 13.1(±4.5) | 11.7(+4.5) |
| Duration of prophylaxis (years) | 1.4(±0.2) | – |
| Haemophilia type | ||
| Haemophilia A | 21 | 10 |
| Haemophilia B | 5 | 2 |
Correlation between school absences and ABR, HJHS and FISH during prophylaxis and on-demand treatment
| BEFORE ENROLMENT | P-VALUE | AFTER ENROLMENT | P-VALUE | |
|---|---|---|---|---|
| Prophylaxis | ||||
| ABR | 0.514 | 0.009 | 0.639 | <0.001 |
| HJHS | 0.325 | 0.112 | 0.156 | 0.446 |
| FISH | −0.751 | <0.001 | −0.694 | <0.001 |
| On-demand | ||||
| ABR | 0.874 | <0.001 | 0.396 | 0.203 |
| HJHS | 0.690 | 0.013 | 0.197 | 0.539 |
| FISH | −0.798 | 0.002 | −0.580 | 0.048 |
Days of school absence (per month) in the year before and after enrolment with HTC
| VARIABLE | BEFORE ENROLMENT MEAN(±SD) | AFTER ENROLMENT MEAN(±SD) | P-VALUE* |
|---|---|---|---|
| Number of days absent (prophylaxis) | 15(+6) | 4(+3) | <0.001 |
| Number of days absent (on-demand) | 10(+5) | 3(+2) | 0.477 |
| Scores during prophylaxis | |||
| ABR | 37.8(±20.0) | 5.8(±4.6) | <0.001 |
| HJHS | 31.1(±18.1) | 4.7(±4.6) | <0.001 |
| FISH | 21.4(±4.2) | 27.9(±3.3) | <0.001 |
| Scores during on-demand treatment | |||
| ABR | 25.5(±19.9) | 8.7(±6.2) | 0.006 |
| HJHS | 13.8(±11.4) | 3.1(±4.2) | 0.002 |
| FISH | 24.6(±4.5) | 29.1(±2.6) | <0.001 |