Figure 1
Figure 2
Figure 3
Types of DNA mutationThe changes in the letters/words in the left hand column demonstrate the type, mechanism and results of DNA mutation_ Every letter of the words that make up the sentence represents a DNA base_ Three consecutive letters codify an amino acid of the protein_
| THE MAN SAW THE DOG HIT THE CAN | Normal DNA | |
|---|---|---|
| THE MAN SAW THE DOT HIT THE CAN | Missense | A change in one DNA base pair resulting in substitution of one amino acid for another in the protein made by the gene |
| THE MAN SAW THE DOG * | Nonsense | A change in one DNA base pair that prematurely signals the cell to stop building a protein, resulting in a shortened protein |
| THE MAN SAW THE DOG * THE CAN | Deletion | Removes a piece of DNA |
| THE MAN SAW THE FAT DOG HIT THE CAN | Insertion | Changes the number of DNA bases in a gene by adding a piece of DNA |
| THE MAN SAW THE *OGH ITT HEC AN | Frameshift | Occurs when the addition or loss of DNA bases changes a gene’s reading frame. The groups of three bases that code a single amino acid are shifted, thereby changing the code |