Carbamazepine Toxicity with Generic Substitution

J Gordon Millichap

doi:10.15844/pedneurbriefs-8-1-6

Carbamazepine Toxicity with Generic Substitution

Pediatric Neurology Briefs

Volume 8 (1994): Issue 1

By: J Gordon Millichap

Open Access

|Jan 1994

Abstract

Two 6-year-old children with carbamazepine (CBZ) toxicity, reported from the University of Miami School of Medicine, were found to have 22% and 41% increases in serum CBZ levels after substitution of Tegretol with the generic brand, Epitol, because of insurance company policies.

References

Gilman JT Alvarez LA Duchowny M Carbamazepine toxicity resulting from generic substitution Neurology 1993 Dec 43 12 2696 2697 10.1212/WNL.43.12.2696 8255480
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Bell WL Crawford IL Shiu GK Reduced bioavailability of moisture-exposed carbamazepine resulting in status epilepticus Epilepsia 1993 Nov-Dec 34 6 1102 1104 10.1111/j.1528-1157.1993.tb02140.x 8243363
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Oles KS Gal P Bioequivalency revisited: Epitol versus tegretol Neurology 1993 Dec 43 12 2435 2436 10.1212/WNL.43.12.2435 8255435
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Articles in this issue

DOI: https://doi.org/10.15844/pedneurbriefs-8-1-6 | Journal eISSN: 2166-6482

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Language: English

Page range: 4 - 4

Published on: Jan 1, 1994

Published by: Pediatric Neurology Briefs Publishers

In partnership with: Paradigm Publishing Services

Keywords:

Carbamazepine Toxicity,

Nystagmus,

Tegretol

© 1994 J Gordon Millichap, published by Pediatric Neurology Briefs Publishers
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 8 (1994): Issue 1