Pathophysiology of Infantile Spasms

J Gordon Millichap

doi:10.15844/pedneurbriefs-7-4-12

Pathophysiology of Infantile Spasms

Pediatric Neurology Briefs

Volume 7 (1993): Issue 4

By: J Gordon Millichap

Open Access

|Apr 1993

Abstract

An age-specific endogenous-convulsant hypothesis implicating corticotropin-releasing hormone (CRH), an excitant neuropeptide suppressed by ACTH/steroids, is proposed for the pathophysiology of massive infantile spasms in a report from the University of Southern California, Los Angeles, CA.

References

Baram TZ Pathophysiology of massive infantile spasms: perspective on the putative role of the brain adrenal axis Ann Neurol 1993 Mar 33 3 231 6 8388675
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Charuvanij A Ouvrier RA Procopis PG Antony JH Fagan ER ACTH treatment in intractable seizures of childhood Brain Dev 1992 Mar 14 2 102 6 1320346 10.1016/S0387-7604(12)80095-7
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Articles in this issue

DOI: https://doi.org/10.15844/pedneurbriefs-7-4-12 | Journal eISSN: 2166-6482

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Language: English

Page range: 32 - 32

Published on: Apr 1, 1993

Published by: Pediatric Neurology Briefs Publishers

In partnership with: Paradigm Publishing Services

Keywords:

Corticotropin-Releasing Hormone,

Endogenous-Convulsant Hypothesis,

Brain-Stem Circuits

© 1993 J Gordon Millichap, published by Pediatric Neurology Briefs Publishers
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 7 (1993): Issue 4