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Fenfluramine: New Treatment for Seizures in Dravet Syndrome. Cover

Fenfluramine: New Treatment for Seizures in Dravet Syndrome.

Open Access
|Mar 2020

References

  1. Lagae L Sullivan J Knupp K Laux L Polster T Nikanorova M FAiRE DS Study Group. Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial Lancet 2020 Dec 394 10216 2243 54 https://doi.org/10.1016/S0140-6736(19)32500-0 31862249
  2. Polster T Individualized treatment approaches: Fenfluramine, a novel antiepileptic medication for the treatment of seizures in Dravet syndrome Epilepsy Behav 2019 Feb 91 99 102 https://doi.org/10.1016/j.yebeh.2018.08.021 30269941
  3. Sourbron J Smolders I de Witte P Lagae L Pharmacological analysis of the anti-epileptic mechanisms of fenfluramine in scn1a mutant zebrafish Front Pharmacol 2017 Apr 8 APR 191 https://doi.org/10.3389/fphar.2017.00191 28428755
  4. Cross JH Caraballo RH Nabbout R Vigevano F Guerrini R Lagae L Dravet syndrome: treatment options and management of prolonged seizures Epilepsia 2019 Dec 60 S3 Suppl 3 S39 48 https://doi.org/10.1111/epi.16334 31904119
  5. Ceulemans B Schoonjans AS Marchau F Paelinck BP Lagae L Five-year extended follow-up status of 10 patients with Dravet syndrome treated with fenfluramine Epilepsia 2016 Jul 57 7 e129 34 https://doi.org/10.1111/epi.13407 27197941
Language: English
Page range: 8 - 8
Submitted on: Feb 24, 2020
Accepted on: Mar 9, 2020
Published on: Mar 12, 2020
Published by: Pediatric Neurology Briefs Publishers
In partnership with: Paradigm Publishing Services

© 2020 Joanna Garcia Pierce, Divakar S Mithal, published by Pediatric Neurology Briefs Publishers
This work is licensed under the Creative Commons Attribution 4.0 License.