Valproate-Induced Reversible Brain Atrophy and Cognitive Deterioration

J Gordon Millichap; John J Millichap

doi:10.15844/pedneurbriefs-28-9-2

Valproate-Induced Reversible Brain Atrophy and Cognitive Deterioration

Pediatric Neurology Briefs

Volume 28 (2014): Issue 9

By: J Gordon Millichap and John J Millichap

Open Access

|Sep 2014

Abstract

Pediatric neurologists at Dalhousie University, Halifax, Nova Scotia, report an 8-year-old boy with rapid cognitive decline after a year-long course of valproate in varying dosages for myoclonic and atypical absence seizures.

References

Lovett M Skidmore DL Mohamed IS Valproate-induced pseudoatrophy: Expanding the clinical and imaging spectrum Pediatr Neurol 2014 Aug 51 2 284 5 10.1016/j.pediatrneurol.2014.04.019 25079580
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Galimberti CA Diegoli M Sartori I Uggetti C Brega A Tartara A Brain pseudoatrophy and mental regression on valproate and a mitochondrial DNA mutation Neurology 2006 Nov 14 67 9 1715 7 10.1212/01.wnl.0000242882.58086.9a 17101920
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Articles in this issue

DOI: https://doi.org/10.15844/pedneurbriefs-28-9-2 | Journal eISSN: 2166-6482

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Language: English

Page range: 66 - 67

Published on: Sep 1, 2014

Published by: Pediatric Neurology Briefs Publishers

In partnership with: Paradigm Publishing Services

Keywords:

Encephalopathy,

Epileptic Seizures,

Neurodegenerative Diseases

© 2014 J Gordon Millichap, John J Millichap, published by Pediatric Neurology Briefs Publishers
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 28 (2014): Issue 9