Brain Alkalosis and Birth Asphyxia Seizures

J Gordon Millichap

doi:10.15844/pedneurbriefs-25-5-2

Brain Alkalosis and Birth Asphyxia Seizures

Pediatric Neurology Briefs

Volume 25 (2011): Issue 5

By: J Gordon Millichap

Open Access

|May 2011

Abstract

Researchers at University of Helsinki, Finland, studied the causal mechanisms of seizures associated with birth asphyxia using 6 day-old rat pups exposed for 1 hour to hypercapnia (20% C02 in inhaled gas), hypoxia (9% 02), or both (asphyxic conditions).

References

Helmy MM Tolner EA Vanhatalo S Voipio J Kaila K Brain alkalosis causes birth asphyxia seizures, suggesting therapeutic strategy Ann Neurol 2011 Mar 69 3 493 500 10.1002/ana.22223 21337602
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Volpe JJ Observing the infant in the early hours after asphyxia Gluck L Intrauterine asphyxia and the developing fetal brain 1977 Chicago Year Book Medical Publ
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Millichap JG Development of seizure patterns in newborn animals; significance of brain carbonic anhydrase Proc Soc Exp Biol Med 1957 Oct 96 1 125 9 13485036
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Pappas A Shankaran S Laptook AR Langer JC Bara R Ehrenkranz RA Hypocarbia and adverse outcome in neonatal hypoxic-ischemic encephalopathy J Pediatr 2011 May 158 5 752 758.e1 10.1016/j.jpeds.2010.10.019 21146184
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Articles in this issue

DOI: https://doi.org/10.15844/pedneurbriefs-25-5-2 | Journal eISSN: 2166-6482

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Language: English

Page range: 34 - 35

Published on: May 1, 2011

Published by: Pediatric Neurology Briefs Publishers

In partnership with: Paradigm Publishing Services

Keywords:

Postexposure,

Neonatal Seizure,

Hypercapnia

© 2011 J Gordon Millichap, published by Pediatric Neurology Briefs Publishers
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 25 (2011): Issue 5