UK Multicenter Randomized Trial of Hormonal Treatments Vs Vigabatrin for Infantile Spasms

J Gordon Millichap

doi:10.15844/pedneurbriefs-24-6-5

UK Multicenter Randomized Trial of Hormonal Treatments Vs Vigabatrin for Infantile Spasms

Pediatric Neurology Briefs

Volume 24 (2010): Issue 6

By: J Gordon Millichap

Open Access

|Jun 2010

Abstract

The UK Infantile Spasms Multicenter Study previously showed that seizure control after 14 days and development at 14 months are better following hormonal treatments (prednisolone or tetracosactide depot) than following vigabatrin.

References

Lux AL Edwards SW Hancock E Johnson AL Kennedy CR Newton RW Vigabatrin with prednisolone or tetracosactide at 14 days: a multicentre, randomised controlled trial Lancet 2004 Nov 364 9447 1773 1778 10.1016/S0140-6736(04)17400-X 15541450
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Darke K Edwards SW Hancock E Johnson AL Kennedy CR Lux AL Developmental and epilepsy outcomes at age 4 years in the UKISS trial comparing hormonal treatments to vigabatrin for infantile spasms: a multi-centre randomized trial Arch Dis Child 2010 May 95 5 382 386 10.1136/adc.2009.160606 20457702
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Articles in this issue

DOI: https://doi.org/10.15844/pedneurbriefs-24-6-5 | Journal eISSN: 2166-6482

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Language: English

Page range: 44 - 45

Published on: Jun 1, 2010

Published by: Pediatric Neurology Briefs Publishers

In partnership with: Paradigm Publishing Services

Keywords:

Vineland Adaptive Behavior Scales,

Hormonal Treatment,

Vigabatrin

© 2010 J Gordon Millichap, published by Pediatric Neurology Briefs Publishers
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 24 (2010): Issue 6