Clinical Manifestations and Viral Triggers of Childhood Multiple Sclerosis: Multinational Study

J Gordon Millichap

doi:10.15844/pedneurbriefs-21-9-3

Clinical Manifestations and Viral Triggers of Childhood Multiple Sclerosis: Multinational Study

Pediatric Neurology Briefs

Volume 21 (2007): Issue 9

By: J Gordon Millichap

Open Access

|Sep 2007

Abstract

The clinical manifestations, outcome, and viral triggers in 137 children (<18 years old) with multiple sclerosis (MS) and 96 controls, enrolled between 2003 and 2006 from diverse multinational geographic regions, were studied by researchers from the Divisions of Neurology and Microbiology, The Hospital for Sick Children, Toronto; Stony Brook University Medical Center, USA; and other centers in Canada, USA, Argentina, Russia, Italy, and Sweden.

References

Banwell B Krupp L Kennedy J Tellier R Tenembaum S Ness J Clinical features and viral serologies in children with multiple sclerosis: a multinational observational study Lancet Neurol 2007 September 6 9 773 781 10.1016/S1474-4422(07)70196-5 17689148
Open DOI Search in Google Scholar Back to article
Midgard R Riise T Svanes C Kvåle G Nyland H Incidence of multiple sclerosis in Møre and Romsdal, Norway from 1950 to 1991. An age-period-cohort analysis Brain 1996 Feb 119 Pt 1 203 211 10.1093/brain/119.1.203 8624682
Open DOI Search in Google Scholar Back to article
Weng WC Yang CC Yu TW Shen YZ Lee WT Multiple sclerosis with childhood onset: report of 21 cases in Taiwan Pediatr Neurol 2006 Nov 35 5 327 334 10.1016/j.pediatrneurol.2006.05.002 17074603
Open DOI Search in Google Scholar Back to article
Orton SM Herrera BM Yee IM Valdar W Ramagopalan SV Sadovnick AD Sex ratio of multiple sclerosis in Canada: a longitudinal study Lancet Neurol 2006 Nov 5 11 932 936 10.1016/S1474-4422(06)70581-6 17052660
Open DOI Search in Google Scholar Back to article
Sadovnick AD Baird PA The familial nature of multiple sclerosis: age-corrected empiric recurrence risks for children and siblings of patients Neurology 1988 Jun 38 6 990 991 10.1212/WNL.38.6.990 3368082
Open DOI Search in Google Scholar Back to article
Hafler DA Compston A Sawcer S Lander ES Daly MJ De Jager PL Risk alleles for multiple sclerosis identified by a genomewide study N Engl J Med 2007 August 30 357 9 851 862 10.1056/NEJMoa073493 17660530
Open DOI Search in Google Scholar Back to article
Lünemann JD Münz C Epstein-Barr virus and multiple sclerosis Curr Neurol Neurosci Rep 2007 May 7 3 253 258 10.1007/s11910-007-0038-y 17488592
Open DOI Search in Google Scholar Back to article
Lipton HL Liang Z Hertzler S Son KN A specific viral cause of multiple sclerosis: one virus, one disease Ann Neurol 2007 Jun 61 6 514 523 10.1002/ana.21116 17455291
Open DOI Search in Google Scholar Back to article
Alvarez-Lafuente R de las Heras V García-Montojo M Bartolomé M Arroyo R Human herpesvirus-6 and multiple sclerosis: relapsing-remitting versus secondary progressive Mult Scler 2007 Jun 13 5 578 583 10.1177/1352458506073116 17548435
Open DOI Search in Google Scholar Back to article
Ascherio A Munger KL Environmental risk factors for multiple sclerosis. Part II: Noninfectious factors Ann Neurol 2007 Jun 61 6 504 513 10.1002/ana.21141 17492755
Open DOI Search in Google Scholar Back to article

Articles in this issue

DOI: https://doi.org/10.15844/pedneurbriefs-21-9-3 | Journal eISSN: 2166-6482

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Language: English

Page range: 67 - 68

Published on: Sep 1, 2007

Published by: Pediatric Neurology Briefs Publishers

In partnership with: Paradigm Publishing Services

Keywords:

Multiple Sclerosis,

Acute Disseminated Encephalomyelitis,

Epstein-Barr Virus

© 2007 J Gordon Millichap, published by Pediatric Neurology Briefs Publishers
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 21 (2007): Issue 9