Mitochondrial Profiles and the Anticonvulsant Effect of the Ketogenic Diet

J Gordon Millichap

doi:10.15844/pedneurbriefs-20-9-5

Mitochondrial Profiles and the Anticonvulsant Effect of the Ketogenic Diet

Pediatric Neurology Briefs

Volume 20 (2006): Issue 9

By: J Gordon Millichap

Open Access

|Sep 2006

Abstract

A study of the anticonvulsant effect of the ketogenic diet (KD) in adolescent rats, at Emory University and other centers, found that the hippocampus responds by inducing mitochondrial biogenesis, enhancing metabolic gene expression, and increasing energy reserves.

References

Bough KJ Wetherington J Hassel B Pare JF Gawryluk JW Greene JG Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet Ann Neurol 2006 Aug 60 2 223 235 10.1002/ana.20899 16807920
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Wilder RM Mayo Clin Bull 1921 2 307
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Millichap JG Jones JD Acid-Base, Electrolyte, and Amino-Acid Metabolism in Children with Petit Mal. Etiologic Significance and Modification by Anticonvulsant Drugs and the Ketogenic Diet Epilepsia 1964 Sep 5 239 255 10.1111/j.1528-1157.1964.tb03331.x 14232248
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Millichap JG Amer J Dis Child 1962 104 506
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Articles in this issue

DOI: https://doi.org/10.15844/pedneurbriefs-20-9-5 | Journal eISSN: 2166-6482

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Language: English

Page range: 68 - 68

Published on: Sep 1, 2006

Published by: Pediatric Neurology Briefs Publishers

In partnership with: Paradigm Publishing Services

Keywords:

Mitochondrial Profiles,

Ketogenic Diet,

Dentate Gyrus

© 2006 J Gordon Millichap, published by Pediatric Neurology Briefs Publishers
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 20 (2006): Issue 9