Valproate-Induced Hyperammonemic Encephalopathy

J Gordon Millichap

doi:10.15844/pedneurbriefs-20-7-5

Valproate-Induced Hyperammonemic Encephalopathy

Pediatric Neurology Briefs

Volume 20 (2006): Issue 7

By: J Gordon Millichap

Open Access

|Jul 2006

Abstract

Valproate-induced hyperammonemic encephalopathy (VHE), predisposing causes, clinical, laboratory, and EEG findings, and therapy are reviewed from the Hospital del Mar, Barcelona, Spain.

References

Segura-Bruna N Rodriguez-Campello A Puente V Roquer J Valproate-induced hyperammonemic encephalopathy Acta Neurol Scand 2006 Jul 114 1 1 7 10.1111/j.1600-0404.2006.00655.x 16774619
Open DOI Search in Google Scholar Back to article
Beghi E Bizzi A Codegoni AM Trevisan D Torri W Valproate, carnitine metabolism, and biochemical indicators of liver function. Collaborative Group for the Study of Epilepsy Epilepsia 1990 May-Jun 31 3 346 352 10.1111/j.1528-1157.1990.tb05387.x 2111771
Open DOI Search in Google Scholar Back to article
König SA Siemes H Bläker F Boenigk E Gross-Selbeck G Hanefeld F Severe hepatotoxicity during valproate therapy: an update and report of eight new fatalities Epilepsia 1994 Sep-Oct 35 5 1005 1015 10.1111/j.1528-1157.1994.tb02546.x 7925143
Open DOI Search in Google Scholar Back to article
Bryant AE 3rd Dreifuss FE Valproic acid hepatic fatalities. III. U.S. experience since 1986 Neurology 1996 Feb 46 2 465 469 10.1212/WNL.46.2.465 8614514
Open DOI Search in Google Scholar Back to article
Aldenkamp A Vigevano F Arzimanoglou A Covanis A Role of valproate across the ages. Treatment of epilepsy in children Acta Neurol Scand Suppl 2006 184 1 13 10.1111/j.1600-0404.2006.00666.x 16776492
Open DOI Search in Google Scholar Back to article
Wheless JW J Child Neurol 2005 20 Suppl 1 S34 S35 10.1177/08830738050200010601
Open DOI Search in Google Scholar Back to article
Golden AS Haut SR Moshé SL Nonepileptic uses of antiepileptic drugs in children and adolescents Pediatr Neurol 2006 Jun 34 6 421 432 10.1016/j.pediatrneurol.2005.08.017 16765818
Open DOI Search in Google Scholar Back to article

Articles in this issue

DOI: https://doi.org/10.15844/pedneurbriefs-20-7-5 | Journal eISSN: 2166-6482

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Language: English

Page range: 52 - 53

Published on: Jul 1, 2006

Published by: Pediatric Neurology Briefs Publishers

In partnership with: Paradigm Publishing Services

Keywords:

Valproate-Induced Hyperammonemic Encephalopathy,

Ornithine Transcarbamylase,

Hyperammonemia

© 2006 J Gordon Millichap, published by Pediatric Neurology Briefs Publishers
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 20 (2006): Issue 7