Two children, ages 3 and 11, who developed multiorgan dysfunction and disseminated intravascular coagulation (DIC) 9 days after the addition of lamotrigine to valproic acid anticonvulsant therapy are reported from the Hospital for Sick Children, Toronto, Canada. Both children developed a flu-like illness with fever, urticarial/maculopapular rash, hepatic and renal dysfunction, hypoalbuminemia, DIC, and one had rhabdomyolysis while being seizure-free. [1]

Lamotrigine - Induced Intravascular Coagulation
DOI: https://doi.org/10.15844/pedneurbriefs-11-12-14 | Journal eISSN: 2166-6482
Language: English
Page range: 96 - 96
Published on: Dec 1, 1997
Published by: Pediatric Neurology Briefs Publishers
In partnership with: Paradigm Publishing Services
Keywords:
© 1997 J Gordon Millichap, published by Pediatric Neurology Briefs Publishers
This work is licensed under the Creative Commons Attribution 4.0 License.