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The Application of Multinomial Logistic Regression Models for the Assessment of Parameters of Oocytes and Embryos Quality in Predicting Pregnancy and Miscarriage Cover

The Application of Multinomial Logistic Regression Models for the Assessment of Parameters of Oocytes and Embryos Quality in Predicting Pregnancy and Miscarriage

Open Access
|Jan 2018

Abstract

Infertility is a huge problem nowadays, not only from the medical but also from the social point of view. A key step to improve treatment outcomes is the possibility of effective prediction of treatment result. In a situation when a phenomenon with more than 2 states needs to be explained, e.g. pregnancy, miscarriage, non-pregnancy, the use of multinomial logistic regression is a good solution. The aim of this paper is to select those features that have a significant impact on achieving clinical pregnancy as well as those that determine the occurrence of spontaneous miscarriage (non-pregnancy was set as the reference category). Two multi-factor models were obtained, used in predicting infertility treatment outcomes. One of the models enabled to conclude that the number of follicles and the percentage of retrieved mature oocytes have a significant impact when prediction of treatment outcome is made on the basis of information about oocytes. The other model, built on the basis of information about embryos, showed the significance of the number of fertilized oocytes, the percentage of at least 7-cell embryos on day 3, the percentage of blasts on day 5, and the day of transfer.

DOI: https://doi.org/10.1515/slgr-2017-0030 | Journal eISSN: 2199-6059 | Journal ISSN: 0860-150X
Language: English
Page range: 7 - 18
Published on: Jan 30, 2018
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Related subjects:

© 2018 Anna Justyna Milewska, Dorota Jankowska, Teresa Więsak, Brian Acacio, Robert Milewski, published by University of Białystok
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.