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Sensitivity and specificity of the method used for ascertainment of healthcare-associated infections in the second Slovenian national prevalence survey Cover

Sensitivity and specificity of the method used for ascertainment of healthcare-associated infections in the second Slovenian national prevalence survey

Open Access
|Jul 2016

Figures & Tables

Table 1

Characteristics of patients surveyed in the University Medical Centre Ljubljana, during the Slovenian national healthcare-associated infections survey (SNHPS) in 2011, eligible for the retrospective medical chart review (RMCR), and of those included into the RMCR.

SNHPS population eligible for RMCRRMCR population
The number of patients16551474
Sex
Women809 (48.9%)738 (50.1%)
Men846 (51.1%)736 (49.9%)
Age (at the time of admission)
Median6060
Range0-980-98
Mean5555
≤49 years589 (35.6%)508 (34.5%)
50-79 years807 (48.8%)715 (48.5%)
≥80 years259 (15.6%)251 (17.0%)
McCabe index (at the time of admission)
nonfatal disease1298 (78.4%)1183 (80.3%)
ultimately fatal disease280 (16.9%)239 (16.2%)
rapidly fatal disease66 (4.0)%52 (3.5%)
unknown11 (0.7%)0 (0.00%)
The length of hospital stay (until SNHPS day)
Median66
Range0 - 3670 - 323
Mean1312
0-3 days594 (35.9%)533 (36.1%)
4-7 days396 (23.9%)369 (25.0%)
8-14 days267 (16.1%)230 (15.6%)
≥15 days398 (24.0%)342 (23.2%)
Operations last month (until SNHPS day)
Surgery571 (34.5%)574 (38.9%)
No surgery1084 (65.5%)900 (61.1%)

ain the case of implant, operations during 12 months, preceding the SNHPS

Table 2

Sensitivity, specificity, positive predictive value and negative predictive value of the method used for ascertaining any of the six types of healthcare-associated infections (HAIs) among 1474 patients enrolled at the University Medical Centre Ljubljana in the Slovenian national HAI prevalence survey in 2011, in comparison to the retrospective medical chart review.

Retrospective medical chart review
HAINo HAITotal
Slovenian national HAI prevalence surveyHAI631679
No HAI813871395
Total7114031474

Sensitivity: 63/71x100=88.7% (95% CI: 79.0%-95.0%) Specificity: 1387/1403x100=98.9% (95% CI: 98.2%-99.4%) Positive predictive value (PPV): 63/79x100=79.7% (95% CI: 64.9%-84.4%)

Negative predictive value (NPV): 1387/1395x100=99.4% (95% CI: 98.4%-99.5%)

Table 3

Sensitivity, specificity of the method used for ascertaining any of the six types of healthcare-associated infections (HAIs) among 1655 eligible patients enrolled at the University Medical Centre Ljubljana in the Slovenian national HAI prevalence survey in 2011, in comparison to the retrospective medical chart review estimated by extrapolation of the results of the retrospective medical chart review conducted among 1474 patients.

Retrospective medical chart review
HAINo HAITotal
Slovenian national HAI prevalence surveyHAI77a1996
No HAI91550b1559
Total8615691655

Sensitivity: 77/86x100=89.5% (95% CI: 81.1%-95.1%)

Specificity: 1550/1569x100=98.8% (95% CI: 98.1%-99.2%)

a 77=PPVx96

b 1550=NPVx1559

Table 4

Sensitivity and specificity of the method used for ascertaining six different types of healthcare-associated infections (HAIs) among 1474 patients enrolled at the University Medical Centre Ljubljana in the Slovenian national HAI prevalence survey in 2011, in comparison to the retrospective medical chart review and respective kappa coefficients by type of HAIs.

Surveillance methodSSIUTIPNLRIBSICRI
RMCR (reference)
Number of HAIs1521198120
Prevalence of HAI episodes*
(%) 95% CI
1.0
(0.6-1.7)
1.4
(0.9-2.2)
1.3
(0.8-2.0)
0.5
(0.3-1.1)
0.8
(0.5-1.4)
0
(0.0-0.3)
SNHPS
Number of HAIs1520267130
Prevalence of HAI episodes*
(%) 95% CI
1.0
(0.6-1.7)
1.4
(0.9-2.1)
1.8
(1.2-2.6)
0.5
(0.2-1.0)
0.9
(0.5-1.5)
0
(0.0-0.3)
Sensitivity
(%) 95% CI
86.7
(59.5-98.3)
76.2
(52.8-91.8)
89.5
(66.9-98.7)
62.5
(24.5-91.5)
91.7
(61.5-99.8)
/
Specificity
(%) 95% CI
99.9
(99.5-100)
99.7
(99.3-99.9)
99.4
(98.8-99.7)
99.9
(99.5-100)
99.9
(99.4-100)
100
(99.8-100)
Kappa coefficient
95% CI
0.87
(0.74-1.00)
0.78
(0.64-0.92)
0.75
(0.61-0.89)
0.67
(0.39-0.94)
0.88
(0.74-1.00)
/

SSI: surgical site infections. UTI: urinary tract infections. PN: pneumoniae. LRI: lower respiratory tract infections, excluding pneumoniae. BSI: bloodstream infections (including microbiologically proven catheter related infections). CRI: catheter-related infections without bloodstream infections. 95% CI: 95% confidence interval

* on the day of SNHPS

* on the day of SNHPS

DOI: https://doi.org/10.1515/sjph-2016-0034 | Journal eISSN: 1854-2476 | Journal ISSN: 0351-0026
Language: English, Slovenian
Page range: 248 - 255
Submitted on: Feb 29, 2016
Accepted on: May 24, 2016
Published on: Jul 28, 2016
Published by: National Institute of Public Health, Slovenia
In partnership with: Paradigm Publishing Services

© 2016 Mojca Serdt, Tatjana Lejko Zupanc, Aleš Korošec, Irena Klavs, published by National Institute of Public Health, Slovenia
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.