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Antitumour Effect of a Mixture of N-Propyl Polysulfides In Vitro Cover

Antitumour Effect of a Mixture of N-Propyl Polysulfides In Vitro

EABR. Experimental and Applied Biomedical Research
Volume 20 (2019): Issue 4 (December 2019)
By: Dragana Djordjevic,  Jelena Milovanovic,  Milena Jurisevic,  Bojana Stojanovic,  Olga Cvetkovic,  Marija Pergal,  Elizabeta Ristanovic,  Danilo Vojvodic,  Milos Simic,  Dragan Manojlovic,  Marija Milovanovic and  Nebojsa Arsenijevic  
Open Access
|Dec 2019

Figures & Tables

Figure 1

Graphs presenting the survival of CT26, B16F10, and 4T1 cells, as well as MSCs, after 24 h of growth in the presence of DPPS and cisplatin. Data are presented as the mean of three independent experiments.
Graphs presenting the survival of CT26, B16F10, and 4T1 cells, as well as MSCs, after 24 h of growth in the presence of DPPS and cisplatin. Data are presented as the mean of three independent experiments.

Figure 2

Representative flow plots showing the percentages of early- and late apoptotic and viable CT26 and 4T1 cells after 24 h of treatment with DPPS (0.01 mg/ml).
Representative flow plots showing the percentages of early- and late apoptotic and viable CT26 and 4T1 cells after 24 h of treatment with DPPS (0.01 mg/ml).

IC50 values (in mM) for 4T1, CT26, and B16F10 cells, as well as mMSCs, after exposure to DPPS and cisplatin for 24 h as determined by MTT assays_ The data are presented as the mean ± SD (standard deviation) from three experiments_

IC50 (mg/ml)
Compound4T1CT26B16F10mMSC
DPPS0.043±0.0060.024±0.0180.023±0.0020.059±0.002
Cisplatin0.029±0.0040.160±0.0920.123±0.0820.028±0.006
DOI: https://doi.org/10.1515/sjecr-2017-0069 | Journal eISSN: 2956-2090 | Journal ISSN: 2956-0454
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Language: English
Page range: 295 - 300
Submitted on: Dec 2, 2017
Accepted on: Dec 13, 2017
Published on: Dec 31, 2019
Published by: University of Kragujevac, Faculty of Medical Sciences
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
n-propyl polysulfides,
tumour cell lines,
cytotoxicity,
in vitro
Related subjects:
Medicine,
Clinical medicine,
Clinical medicine, other

© 2019 Dragana Djordjevic, Jelena Milovanovic, Milena Jurisevic, Bojana Stojanovic, Olga Cvetkovic, Marija Pergal, Elizabeta Ristanovic, Danilo Vojvodic, Milos Simic, Dragan Manojlovic, Marija Milovanovic, Nebojsa Arsenijevic, published by University of Kragujevac, Faculty of Medical Sciences
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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