Figure 1
Graphs presenting the survival of CT26, B16F10, and 4T1 cells, as well as MSCs, after 24 h of growth in the presence of DPPS and cisplatin. Data are presented as the mean of three independent experiments.
Table 1
IC50 values (in mM) for 4T1, CT26, and B16F10 cells, as well as mMSCs, after exposure to DPPS and cisplatin for 24 h as determined by MTT assays. The data are presented as the mean ± SD (standard deviation) from three experiments.
| IC50 (mg/ml) | ||||
|---|---|---|---|---|
| Compound | 4T1 | CT26 | B16F10 | mMSC |
| DPPS | 0.043±0.006 | 0.024±0.018 | 0.023±0.002 | 0.059±0.002 |
| Cisplatin | 0.029±0.004 | 0.160±0.092 | 0.123±0.082 | 0.028±0.006 |
Figure 2
Representative flow plots showing the percentages of early- and late apoptotic and viable CT26 and 4T1 cells after 24 h of treatment with DPPS (0.01 mg/ml).