Synthesis and Characterization of Zinc(II)-Complexes with S-Alkyl Derivatives of Thiosalicylic Acid

Milos V. Nikolic; Marina Z. Mijajlovic; Dusan Lj. Tomovic; Andriana M. Bukonjic; Verica V. Jevtic; Zoran R. Ratkovic; Srecko R. Trifunovic; Gordana P. Radic

doi:10.1515/sjecr-2017-0005

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Synthesis and Characterization of Zinc(II)-Complexes with S-Alkyl Derivatives of Thiosalicylic Acid

EABR. Experimental and Applied Biomedical Research

Volume 19 (2018): Issue 2 (June 2018)

By: Milos V. Nikolic, Marina Z. Mijajlovic, Dusan Lj. Tomovic, Andriana M. Bukonjic, Verica V. Jevtic, Zoran R. Ratkovic, Srecko R. Trifunovic and Gordana P. Radic

Open Access

|Jul 2018

Abstract

New zinc(II)-complexes with S-alkyl derivatives of thiosalicylic acid (alkyl = benzyl-(L1), methyl-(L2), ethyl-(L3), propyl-(L4), butyl-(L5)) have been synthesized and characterized by elemental microanalysis, IR spectroscopy, and ¹H and ¹³C NMR spectroscopy. The S-alkyl derivatives of thiosalicylic acid were prepared by alkylation of thiosalicylic acid by adding alkyl halides to an alkaline water-ethanol solution, while the corresponding zinc(II)-complexes were obtained via the direct reaction of ZnCl₂ with S-alkyl derivatives of thiosalicylic acid in water. Based on the microanalysis results and the IR and NMR spectra of the S-alkyl derivatives of thiosalicylic acid and the corresponding zinc(II)-complexes, we concluded that the ligands are bidentately coordinated to the zinc(II)-ion.

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Articles in this issue

DOI: https://doi.org/10.1515/sjecr-2017-0005 | Journal eISSN: 2956-2090 | Journal ISSN: 2956-0454

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Language: English

Page range: 113 - 117

Submitted on: Feb 2, 2017

Accepted on: Feb 12, 2017

Published on: Jul 17, 2018

Published by: University of Kragujevac, Faculty of Medical Sciences

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

S-alkyl derivatives of thiosalicylic acid,

zinc(II)-complexes,

elemental microanalysis,

IR and NMR spectroscopy

Related subjects:

Medicine,

Clinical medicine,

Clinical medicine, other

© 2018 Milos V. Nikolic, Marina Z. Mijajlovic, Dusan Lj. Tomovic, Andriana M. Bukonjic, Verica V. Jevtic, Zoran R. Ratkovic, Srecko R. Trifunovic, Gordana P. Radic, published by University of Kragujevac, Faculty of Medical Sciences
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 19 (2018): Issue 2 (June 2018)