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Decreased serum levels of sex steroids associated with osteoporosis in a group of Romanian male patients Cover

Decreased serum levels of sex steroids associated with osteoporosis in a group of Romanian male patients

Revista Romana de Medicina de Laborator
Volume 24 (2016): Issue 1 (March 2016)
By: Florina Ligia Popa,  Mihaela Stanciu,  Adrian Bighea,  Mihai Berteanu,  Ioan Gheorghe Totoianu and  Maria Rotaru  
Open Access
|Mar 2016

References

  1. 1. Rao SS, Budhwar N. Ashfaque A. Osteoporosis in men. Am Fam Physician. 2010 Sep 1;82(5):503-508.
    Search in Google Scholar
  2. 2. Herrera A, Lobo-Escolar A, Mateo J, Gil J, Ibarz E, Gracia L. Male osteoporosis: A review. World J Orthop. 2012 December 18;3(12):223-34. DOI: 10.5312/wjo.v3.i12.22310.5312/wjo.v3.i12.223355732423362466
    Search in Google Scholar
  3. 3. Lambert JK, Zaidi M, Mechanick JI. Male osteoporosis: epidemiology and the pathogenesis of aging bones. Curr Osteoporos Rep. 2011 Dec;9(4):229-36. DOI: 10.1007/s11914-011-0066-z10.1007/s11914-011-0066-z21853294
    Search in Google Scholar
  4. 4. Meier C, Nguyen TV, Handelsman DJ, Schindler C, Kushnir MM, Rockwood AL, et al. Endogenous Sex Hormones and Incident Fracture Risk in Older Men. The Dubbo Osteoporosis Epidemiology Study. Arch Intern Med. 2008 Jan;168(1):47-54. DOI: 10.1001/archinternmed.2007.210.1001/archinternmed.2007.218195195
    Search in Google Scholar
  5. 5. Martin AC. Osteoporosis in men: a review of endogenous sex hormones and testosterone replacement therapy. J Pharm Pract. 2011 Jun; 24(3):307-15. DOI: 10.1177/089719001039771610.1177/089719001039771621676854
    Search in Google Scholar
  6. 6. Drake MT, Murad MH, Mauck KF, Lane MA, Undavalli C, Elraiyah T, et al. Clinical review. Risk factors for low bone mass-related fractures in men: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2012 Jun;97(6):1861-70. DOI: 10.1210/jc.2011-305810.1210/jc.2011-305822466344
    Search in Google Scholar
  7. 7. Frenkel B, Hong A, Baniwal SK, Coetzee GA, Ohlsson C, Khalid O, et al. Regulation of adult bone turnover by sexsteroids. J Cell Physiol. 2010;224(2):305–10. DOI: 10.1002/jcp.2215910.1002/jcp.22159577023020432458
    Search in Google Scholar
  8. 8. Khosla S, Oursler MJ, Monroe DG. Estrogen and the skeleton. Trends Endocrin Met. 2012; 23(11):576–81. DOI: 10.1016/j.tem.2012.03.00810.1016/j.tem.2012.03.008342438522595550
    Search in Google Scholar
  9. 9. Rochira V, Balestrieri A, Madeo B, Zirilli L, Granata ARM, Carani C. Osteoporosis and male age-related hypogonadism: role of sex steroids on bone (patho) physiology. Eur J Endocrinol. 2006 Febr;154(2):175–85. DOI: 10.1530/eje.1.0208810.1530/eje.1.0208816452530
    Search in Google Scholar
  10. 10. Chin KY, Ima-Nirwana S. Sex Steroids and Bone Health Status in Men. Int J Endocrinol. 2012; 10:404-10. DOI: 10.1155/2012/20871910.1155/2012/208719348840323150727
    Search in Google Scholar
  11. 11. Carnevale V, Romagnoli E, Cipriani C, Del Fiacco R, Piemonte S, Pepe J, et al. Sex hormones and bone health in males. Arch Biochem Biophys. 2010;503:110–7. DOI: 10.1016/j.abb.2010.07.00110.1016/j.abb.2010.07.00120627086
    Search in Google Scholar
  12. 12. El Maghraoui A, Ouzzif Z, Mounach A, Ben-Ghabrit A, Achemlal L, Bezza A, et al. The relationship between sex steroids, bone turnover and vertebral fracture prevalence in asymptomatic men. Bone. 2011 Oct;49(4):853-7. DOI: 10.1016/j.bone.2011.06.02210.1016/j.bone.2011.06.02221723429
    Search in Google Scholar
  13. 13. Ward KA, Pye SR, Adams JE. Influence of age and sex steroids on bone density and geometry in middle-aged and elderly European men. Osteoporos Int. 2011 May;22(5):1513–23. DOI: 10.1007/s00198-010-1437-510.1007/s00198-010-1437-5307304021052641
    Search in Google Scholar
  14. 14. Barrett-Connor E, Mueller JE, von Mühlen DG, Laughlin GA, Schneider DL, Sartoris DJ. Low levels of estradiol are associated with vertebral fractures in older men, but not women: the Rancho Bernardo Study. J Clin Endocrinol Metab. 2000 Jan;85(1):219–23. DOI: 10.1210/jc.85.1.219 DOI: 10.1210/jcem.85.1.632710.1210/jc.85.1.219
    Search in Google Scholar
  15. 15. Finkelstein JS, Lee H, Burnett-Bowie SAM. Gonadal steroids and body composition, strength, and sexual function in men. N Engl J Med. 2013 Sep;369(11):1011–22. DOI: 10.1056/NEJMoa120616810.1056/NEJMoa1206168414276824024838
    Search in Google Scholar
  16. 16. Mellstrom D, Johnell O, Ljunggren O, Eriksson AL, Lorentzon M, Mallmin H, et al. Free testosterone is an independent predictor of BMD and prevalent fractures in elderly men: MrOS Sweden. J Bone Miner Res. 2006 Apr;21(4):529-35. DOI: 10.1359/jbmr.06011010.1359/jbmr.06011016598372
    Search in Google Scholar
  17. 17. Goderie-Plomp HW, van der Klift M, de Ronde W, Hofman A, de Jong FH & Pols HAP. Endogenous sex hormones, sex hormone binding globulin, and the risk of incident vertebral fractures in elderly men and women: the Rotterdam Study. J Clin Endocrinol Metab. 2004 Jul;89(7):3261-9. DOI: 10.1210/jc.2002-02204110.1210/jc.2002-02204115240601
    Search in Google Scholar
  18. 18. Ree EJ, Oh KW, Lee WY, Kim SW, Oh ES, Baek KH, et al. Age, body mass index, current smoking history, and serum insulin-like growth factor-I levels associated with bone mineral density in middle-aged Korean men. J Bone Miner Metab. 2004;22(4):392-8. DOI: 10.1007/s00774-003-0500-010.1007/s00774-003-0500-015221500
    Search in Google Scholar
  19. 19. Compston J, Bowring C, Cooper A, Cooper C, Davies C, Francis R, et al. Guidelines for the diagnosis and management of osteoporosis in postmenopausal women and older men in the UK: National Osteoporosis Guideline Group (NOGG). Maturitas. 2013 Aug;75(4):392-6. DOI: 10.1016/j.maturitas.2013.05.01310.1016/j.maturitas.2013.05.01323810490
    Search in Google Scholar
  20. 20. Gielen E, Vanderschueren D, Callewaert F, Boonen S. Osteoporosis in men. Best Practice and Research 2011; 25(2):321–35. DOI: 10.1016/j.beem.2010.08.01210.1016/j.beem.2010.08.01221397201
    Search in Google Scholar
  21. 21. Khosla S. Update in male osteoporosis. J Clin Endocrinol Metab. 2010 Jan;95(1):3-10. DOI: 10.1210/jc.2009-174010.1210/jc.2009-1740280548320056806
    Search in Google Scholar
  22. 22. Sutton RAL, Dian L, Guy P. Osteoporosis in men: An underrecognized and undertreated problem. BCMJ. 2011 Dec;53(10):535-40.
    Search in Google Scholar
  23. 23. Woo J, Kwok T, Leung JCS, Ohlsson C, Vandenput L, Leung PC. Sex steroids and bone health in older Chinese men. Osteoporosis International 2011; 23(5):1553–62. DOI: 10.1007/s00198-011-1552-y10.1007/s00198-011-1552-y21318439
    Search in Google Scholar
  24. 24. Bjornerem A, Emaus N, Berntsen GK, Joakimsen RM, Fonnebo V, Wilsgaard T, et al. Circulating sex steroids, sex hormone-binding globulin, and longitudinal changes in forearm bone mineral density in postmenopausal women and men: the Tromso study. Calcif Tissue Int. 2007 Aug;81(2):65-72. DOI: 10.1007/s00223-007-9035-z10.1007/s00223-007-9035-z17612780
    Search in Google Scholar
  25. 25. Cauley JA, Ewing SK, Taylor BC, Fink HA, Ensrud KE, Bauer DC, et al. Sex steroid hormones in older men: Longitudinal associations with 4.5-year change in hip bone mineral density—The Osteoporotic Fractures in Men Study (MrOs). J Clin Endocrinol Metab. 2010 Sep;95(9):4314-23. DOI: 10.1210/jc.2009-263510.1210/jc.2009-2635293605520554716
    Search in Google Scholar
  26. 26. Keles I, Aydin G, Basar MM, Hairan M, Atalar E, Orkun S, et al. Endogenous sex steroids and bone mineral density in healthy men. Joint Bone Spine. 2006 Jan;73(1):80-5. DOI: 10.1016/j.jbspin.2005.04.00310.1016/j.jbspin.2005.04.00316087380
    Search in Google Scholar
  27. 27. Venkat K, Desai M, Arora MM, Singh P, Khatkhatay MI. Age-related changes in sex steroid levels influence bone mineral density in healthy Indian men. Osteoporos Int. 2009 Jun; 20 (6):955-62. DOI: 10.1007/s00198-008-0765-110.1007/s00198-008-0765-118839048
    Search in Google Scholar
  28. 28. Amin S, Zhang Y, Felson DT, Sawin CT, Hannan MT, Wilson PV, et al. Estradiol, testosterone, and the risk for hip fractures in elderly men from the Framingham Study. Am J Med. 2006 May;119(5):426-33. DOI: 10.1016/j.amjmed.2005.10.04810.1016/j.amjmed.2005.10.04816651055
    Search in Google Scholar
  29. 29. Vandenput L, Ohlsson C. Sex steroid metabolism in the regulation of bone health in men. J Steroid Biochem Mol Biol. 2010 Aug;121(3-5):582-88. DOI: 10.1016/j.jsbmb.2010.03.06710.1016/j.jsbmb.2010.03.06720362055
    Search in Google Scholar
  30. 30. Paller CJ, Shielst MS, Rohrmann S, Basaria S, Rifai N, Nelson W, et al. Relationship of sex steroid hormones with bone mineral density (BMD) in a nationally representative sample of men. Clin Endocrinol (Oxf). 2009 Jan;70(1):26-34. DOI: 10.1111/j.1365-2265.2008.03300.x10.1111/j.1365-2265.2008.03300.x349446618485120
    Search in Google Scholar
  31. 31. Ensrud KE, Lewis CE, Lambert LC, Taylor BC, Fink HA, Barrett-Connor E, et al. Endogenous sex steroids, weight change and rates of hip bone loss in older men: the MrOS study. Osteoporos Int. 2006 Sep;17(9):1329-36. DOI: 10.1007/s00198-006-0088-z10.1007/s00198-006-0088-z16767524
    Search in Google Scholar
  32. 32. Araujo A, Travison TG, Leder BZ, McKinlay JB. Correlations between serum testosterone, estradiol, and sex hormone-binding globulin and bone mineral density in a diverse sample of men. J Clin Endocrinol Metab. 2008 Jun;93(6):2135-41. DOI: 10.1210/jc.2007-146910.1210/jc.2007-1469243564418364385
    Search in Google Scholar
  33. 33. Fink HA, Ewing SK, Ensrud KE, Barett-Connor E, Taylor BC, Cauley JA, et al. Association of testosterone and estradiol deficiency with osteoporosis and rapid bone loss in older men. J Clin Endocrinol Metab. 2006 Oct;91(10):3908-15. DOI: 10.1210/jc.2006-017310.1210/jc.2006-017316849417
    Search in Google Scholar
DOI: https://doi.org/10.1515/rrlm-2016-0014 | Journal eISSN: 2284-5623 | Journal ISSN: 1841-6624
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Language: English
Page range: 75 - 82
Submitted on: Sep 16, 2015
|
Accepted on: Feb 16, 2016
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Published on: Mar 19, 2016
Published by: Romanian Association of Laboratory Medicine
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
sex steroids,
bone mineral density,
men
Related subjects:
Life sciences,
Molecular biology,
Biochemistry,
Human biology,
Microbiology and virology

© 2016 Florina Ligia Popa, Mihaela Stanciu, Adrian Bighea, Mihai Berteanu, Ioan Gheorghe Totoianu, Maria Rotaru, published by Romanian Association of Laboratory Medicine
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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