Association of neutrophil-to-lymphocyte ratio and microalbuminuria in patients with normal eGFR

Aysun Aybal Kutlugun; Fatma Ayerden Ebinc; Mujgan Tek Ozturk; Fatma Kaplan Efe; İbrahim Karadag; Murat Eser; Oktay Unsal; Serdar Karakaya

doi:10.1515/rjim-2017-0036

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Association of neutrophil-to-lymphocyte ratio and microalbuminuria in patients with normal eGFR

Romanian Journal of Internal Medicine

Volume 56 (2018): Issue 1 (March 2018)

By: Aysun Aybal Kutlugun, Fatma Ayerden Ebinc, Mujgan Tek Ozturk, Fatma Kaplan Efe, İbrahim Karadag, Murat Eser, Oktay Unsal and Serdar Karakaya

Open Access

|Mar 2018

Abstract

Aims. The aim of this study was to evaluate the association between neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and microalbuminuria in patients with normal estimated glomerular filtration rate (eGFR).

Methods. 174 patients who had eGFR ≥ 60 mL/min/1.73 m² were studied. Patients were divided into two groups according to the urinary albumin excretion as microalbuminuric group (n = 105) and normoalbuminuric group (n = 69). NLR and PLR levels were calculated.

Results. NLR was significantly higher (p < 0.05) in microalbuminuric patients (1.91 ± 0.70) compared with normoalbuminuric patients (1.63 ± 0.53). A positive correlation was found between urine albumin excretion and NLR in the whole study group (r = 0.214, p < 0.005).

Conclusions. Higher NLR levels were found in microalbuminuric patients with normal eGFR. Also a significant positive correlation was observed between albuminuria and NLR.

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Articles in this issue

DOI: https://doi.org/10.1515/rjim-2017-0036 | Journal eISSN: 2501-062X | Journal ISSN: 1220-4749

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Language: English

Page range: 21 - 26

Submitted on: Jul 27, 2017

Published on: Mar 7, 2018

Published by: N.G. Lupu Internal Medicine Foundation

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

Microalbuminuria,

neutrophil-to-lymphocyte ratio,

platelet-to-lymphocyte ratio

Related subjects:

Medicine,

Clinical medicine,

Internal medicine,

Internal medicine, other,

Cardiology,

Gastroenterology,

Rheumatology

© 2018 Aysun Aybal Kutlugun, Fatma Ayerden Ebinc, Mujgan Tek Ozturk, Fatma Kaplan Efe, İbrahim Karadag, Murat Eser, Oktay Unsal, Serdar Karakaya, published by N.G. Lupu Internal Medicine Foundation
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 56 (2018): Issue 1 (March 2018)