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Liver Fibrosis: Causes and Methods of Assessment, A Review Cover

Liver Fibrosis: Causes and Methods of Assessment, A Review

Open Access
|Dec 2015

Full Article

ABBREVIATIONS

AE2

Anion exchanger 2

AIP

Autoimmune pancreatitis

ALP

Alkaline phosphatase

ALT

Alanine aminotransferase;

AMAs

Antimitochondrial antibodies

ANIT

Alpha-naphthylisothiocyanate

APRI

Aspartate-to-Platelet Ratio Index

ARFI

Acoustic Radiation Force Impulse

AST

Aspartate AminoTransferase

AST/ALT

Aspartate aminotransferase/alanine aminotransferase ratio index

AUROC

Area under the receiver operating characteristic curve

BMI

Body mass index

CAP

Controlled attenuation parameter

CFTR

Cystic fibrosis transmembrane conductance regulator

CHB

Chronic hepatitis B

CHC

Chronic hepatitis C

CI

Confidence interval

CLDs

Chronic liver diseases

CRBP

Cellular retinol-binding proteins

CRC

Colorectal cancer

CTGF

Connective tissue growth factor

DCC

3.5-diethoxycarbonyl-1.4-dihydrocollidine

ECM

Extracellular matrix

EMT

Epithelial-mesenchymal transition

ERCP

Endoscopic retrograde cholangio-pancreaticography

ETM

Epithelial-mesenchymal transition

FGF-2

Fibroblast growth factor-2

FLI

Fatty liver index

FT

FibroTest®

G1

Genotype 1

GFAP

Glial fibrillary acidic protein

GGT

Gamma-Glutamyl Transpeptidase

Gnt-V

N-acetyl glucosaminyltransferase V

HBV

Hepatitis B virus

HCC

Hepatocellular carcinomas

HCV

Hepatitis C virus

HD

Hemodialysis

HGF

Hepatocyte growth factor

HSC

Hepatic stellate cells

IGF1

Insulin-like growth factor 1

ILK

Integrin-linked kinase

IQR

Interquartile range

KO

Knockout

kPa

Kilopascal

KS

King’s score

LB

Liver biopsy

LRAT

Lecithin-retinol acyltransferase

LSM

Liver Stiffness Measurement

LXR

Liver X receptor

MCP-1

Monocyte chemoattractant protein-1

MFs

Myofibroblasts

MRCP

Magnetic resonance cholangio-pancreaticography

NAFLD

Nonalcoholic fatty liver disease

NASH

Nonalcoholic steatohepatitis

NGF

Nerve growth factor

NPV

Negative predictive value

OR

Odds ratio

pANCA

Perinuclear antineutrophil cytoplasmatic antibody

PBC

Primary biliary cirrhosis

PDC-E2

E2 subunit of pyruvate dehydrogenase complex

PDGF

Platelet-derived growth factor

PPARγ

Peroxisome proliferator activated receptor γ

PPV

Positive predictive value;

PSC

Primary sclerosing cholangitis

PT

Prothrombin time

RI

Ribonuclease inhibitor

ROI

Region of interest

SF

Significant fibrosis

SSI

Supersonic shear imaging

STAP

Stellate cell activation-associated protein

TE

Transient elastography

TGFβ

Transforming growth factor β

UDCA

Ursodeoxycholic acid

US

Ultrasonography

VCTE

Vibration-controlled transient elastography

VDR

Farnesoid X receptor (FXR), vitamin D receptor

VEGF

Vascular endothelial growth factor

DOI: https://doi.org/10.1515/rjim-2015-0039 | Journal eISSN: 2501-062X (formerly 1220-4749) | Journal ISSN: 1220-4749
Language: English, Romanian
Page range: 304 - 314
Submitted on: May 5, 2015
Published on: Dec 10, 2015
Published by: N.G. Lupu Internal Medicine Foundation
In partnership with: Paradigm Publishing Services

© 2015 Ali Erfani Karimzadeh Toosi, published by N.G. Lupu Internal Medicine Foundation
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.