Figure 1
Intraoperative details and postoperative complications
| Operative time, min, median (range) | 134 (20-373) |
| Blood loss, ml, median (range) | 200 (<50-4000) |
| No. of resected specimens pr. procedure, 1/ 2/ 3/ 4/ 5/ 7 Total | 204/ 66/ 12/ 12/ 1/ 1 432 |
| Total No. of removed lesions | 448 |
| Max diameter of lesions, mm, median d (range) | 22 (4-80) |
| Resection margin, R0 / R1 (n=294) Median, mm (range) | 239 / 55 3 (0-30) |
| Conversion to open access, n (%) | 5 (1.7) |
| Combination with RFA or cryoablation, n (%) | 20 (6.7) |
| Simultaneous resection with primary, n (%) | 11 (3.7) |
| Postoperative complications, Accordion, n (%) Grade 2 / Grade 3 / Grade 4 / Grade 5 | 43 (14.5) 19/ 14/ 8/ 2 |
| Postoperative hospital stay, days, median (range) | 3 (1-35) |
Patient characteristics (N = 296)
| Age, years, median (range) | 66 (29–89) |
| Gender (female/male) | 110/186 |
| BMI, kg, median, (range) | 25 (16–42) |
| ASA score | 2 (1–3) |
| Synchronous/metachronous | 224/72 |
| Neoadjuvant chemotherapy yes/no/no information | 122/168/6 |
| Preoperative CEA, median (range) | 12 (1–498) |
| Extrahepatic disease at the time of liver resection, n (%) | 21 (7.1) |
| Liver involvement (unilobar/bilobar) | 233/63 |
Long-term outcomes
| Disease recurrence, n (%) | 189 (64) |
| Liver recurrence, n (%) | 146 (49.3) |
| Isolated liver recurrence, n (%) | 75 (25.3) |
| Recurrence in resection bed, n (%) | 7 (2.3) |
| Repeat liver resection, n (%) | 69 (23.3) |
| Secondary RFA, n (%) | 14 (4.7) |
| Median overall survival, months (95% confidential interval) | 56 (46-66) |
| 3-year overall survival rate, % | 68 |
| 5-year overall survival rate, % | 48 |
| 3-year recurrence-free survival rate, % | 36 |
| 5-year recurrence-free survival rate, % | 34 |