Have a personal or library account? Click to login

Combined local and systemic bleomycin administration in electrochemotherapy to reduce the number of treatment sessions

Radiology and Oncology
Volume 50 (2016): Issue 1 (March 2016)
By:
Open Access
|Feb 2016

Figures & Tables

Figure 1.

Case number 6. (A) before combined treatment, a fibrosarcoma which failed to respond to the first ECT treatment. (B) CR was obtained after combined treatment.
Case number 6. (A) before combined treatment, a fibrosarcoma which failed to respond to the first ECT treatment. (B) CR was obtained after combined treatment.

Figure 2.

Graph shows the objective response rate obtained in the second session, in a comparison between combined bleomycin administration, both systemic and local (S+L), and systemic alone (S Alone).ECT = electrochemotherapy
Graph shows the objective response rate obtained in the second session, in a comparison between combined bleomycin administration, both systemic and local (S+L), and systemic alone (S Alone).ECT = electrochemotherapy

List of group 2 patients (control) treated using a repetition of the first session

PatientBreedLocation of the tumorWeight (kg)HistologyStageSize (cm3)Response 1 (ECT)Response 2 (ECT)
12Cross-breedOral30MelanomaI158.2PRSD
13Cross-breedOral21SarcomaIII79.76PRSD
14Cross-breedOral20CarcinomaIII96.5PRSD
15Toy PoodleOral5FibrosarcomaII23.23PDPD
16Cross-breedOral11MelanomaII73.8PRSD
17Cross-breedOral16SchwannomaII467.02PDSD
18Cross-breedOral6Squamous cell carcinomaII12.32SDSD
19Labrador retrieverOral32FibrosarcomaII40PRSD
20RottweilerOral34MelanomaII33PRPR
21German ShepherdOral39FibrosarcomaII101.18PRPD
22Cross-breedOral14MelanomaII14.4PRPR

List of group 1 patients treated using combined systemic and local bleomycin administration in the second treatment session

PatientBreedLocation of the tumorWeight (kg)HistologyStageSize (cm3)Response 1 (ECT)Response 2 (S+L)
1Labrador retrieverOral32MastocytomaII10.6PRCR
2Cross-breedOral21Squamous cell carcinomaII36.2SDPR
3Labrador retrieverNasal32Squamous cell carcinomaII43.5PRCR
4YorkshirePerianal5Solid differentiated carcinomaIV173.8SDSD
5Cross-breedElbow12SchwannomaI67.6SDPR
6RottweilerOral37FibrosarcomaI109.5SDCR
7Labrador retrieverNasal38Squamous cell carcinomaIII42.4SDPR
8BoxerOral37FibrosarcomaIII112.2SDPR
9Cocker spanielOral15MelanomaII8.7PRCR
10BeagleOral16MelanomaIII12.4PRCR
11Cocker spanielOral16MelanomaIII26.64PRCR
DOI: https://doi.org/10.1515/raon-2016-0015 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Journal RSS Feed
Language: English
Page range: 58 - 63
Submitted on: Oct 20, 2015
Accepted on: Jan 18, 2016
Published on: Feb 16, 2016
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
electrochemotherapy,
combined treatment,
systemic and local,
bleomycin,
resistant
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Haematology, oncology,
Radiology

© 2016 Felipe Maglietti, Matias Tellado, Nahuel Olaiz, Sebastian Michinski, Guillermo Marshall, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Previous articleVolume 50 (2016): Issue 1 (March 2016)Next article