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Implant-prosthetic rehabilitation after radiation treatment in head and neck cancer patients: a case-series report of outcome Cover

Implant-prosthetic rehabilitation after radiation treatment in head and neck cancer patients: a case-series report of outcome

Open Access
|Feb 2016

Figures & Tables

A patient after segmental resection of the left mandible body due to cancer, with two implants as seen on the radiograph (A). The patient received an implant-supported lower denture (B), where the retention was based on the Locator attachments (C).
A patient after segmental resection of the left mandible body due to cancer, with two implants as seen on the radiograph (A). The patient received an implant-supported lower denture (B), where the retention was based on the Locator attachments (C).
A patient after surgical treatment of oropharyngeal carcinoma. Segmental resection of the left mandible body is visible on the radiograph (A). Patient received implant-supported lower and upper dentures (B) with retention based on the SynCone double crowns (C).
A patient after surgical treatment of oropharyngeal carcinoma. Segmental resection of the left mandible body is visible on the radiograph (A). Patient received implant-supported lower and upper dentures (B) with retention based on the SynCone double crowns (C).
The Kaplan-Meier curve for the survival of the implants. 95% confidence intervals and censored data are included on the plot.
The Kaplan-Meier curve for the survival of the implants. 95% confidence intervals and censored data are included on the plot.

Predictors of the loaded implants’ success_

ParameterOdds ratio for the loaded implants’ success (95% confidence interval)p
Patient's age at prosthetic rehabilitation0.66 (0.49–0.80)0.0075
Healing time after the implant insertion1.09 (0.53–2.73)1.0000
Male gender8.64 (1.99–60.09)0.1456
Smoker2.44 (0.57–16.95)1.0000
Number of the implants supporting the denture0.78 (0.24–1.94)1.0000
Denture attachment system
 Locator vs bar12.33 (1.98–104.98)0.1456
 SynCone vs bar6.00 (1.15–32.68)0.4416
 SynCone vs Locator0.48 (0.06–2.65)1.0000
Upper jaw0.54 (0.14–2.30)1.0000

Predictors of the implant failure_

ParameterHazard ratio (95% confidence interval)p
Patient's age at implant insertion in years1.05 (0.99–1.12)1.0000
Time interval between the radiation therapy and the implant insertion in years0.99 (0.92–1.07)1.0000
Female gender2.74 (0.82–9.10)1.0000
Smoker0.72 (0.19–2.66)1.0000
Lower jaw0.84 (0.23–3.09)1.0000
Transplanted bone12.37 (3.87–39.56)0.0003
HBO administered0.31 (0.10–0.98)0.4753

Summary of the loaded implants’ success according to the factors of interest_

ParameterAll loaded implants (n = 89)Successful loaded implants (n = 79)Unsuccessful loaded implants (n = 10)
Median patient's age at prosthetic rehabilitation in years (range)59.1 (49.3–79.2)58.9 (49.3–67.9)71.7 (59.1–79.2)
Median healing time after the implant insertion in months (range)15.1 (4.3–54.4)15.2 (4.3–54.4)13.0 (4.3–24.6)
Patient's gender
 Female, n (%)33 (37%)25 (32%)8 (80%)
 Male, n (%)56 (63%)54 (68%)2 (20%)
Smoking
 No, n (%)57 (64%)49 (62%)8 (80%)
 Yes, n (%)32 (36%)30 (38%)2 (20%)
Median number of the implants supporting the denture (range)4 (2–5)4 (2–5)4
Implant denture system
 Bar, n (%)10 (11%)6 (8%)4 (40%)
 Locator, n (%)39 (44%)37 (47%)2 (20%)
 SynCone, n (%)40 (45%)36 (45%)4 (40%)
Jaw
 Upper, n (%)25 (28%)21 (27%)4 (40%)
 Lower, n (%)64 (72%)58 (73%)6 (60%)
Bone
 Native, n (%)86 (97%)76 (96%)10 (100%)
 Transplanted, n (%)3 (3%)3 (4%)0 (0%)
HBO administered
 Yes75 (84%)65 (82%)10 (100%)
 No14 (16%)14 (18%)0 (0%)

Summary of the implant survival according to the factors of interest_

ParameterAll implants (n = 100)Survived implants (n = 88)Failed implants (n = 12)
Patient's median age at implant insertion in years (range)58.3 (46.7–77.2)61.5 (46.7–77.2)57.9 (46.7–77.2)
Median time interval between radiation therapy and implant insertion in years (range)3.8 (1.1–38.1)3.2 (1.1–38.1)5.2 (2.4–12.8)
Patient's gender
 Female, n (%)40 (40%)32 (36%)8 (67%)
 Male, n (%)60 (60%)56 (64%)4 (33%)
Smoking
 No, n (%)66 (66%)57 (65%)9 (75%)
 Yes, n (%)34 (34%)31 (35%)3 (25%)
Implant system
 Astra, n (%)18 (18%)18 (20%)0 (0%)
 Straumann, n (%)22 (22%)17 (20%)5 (42%)
 Ankylos, n (%)60 (60%)53 (60%)7 (58%)
Jaw
 Lower, n (%)72 (72%)63 (72%)9 (75%)
 Upper, n (%)28 (28%)25 (28%)3 (25%)
Bone
 Native, n (%)92 (92%)85 (97%)7 (58%)
 Transplanted, n (%)8 (8%)3 (3%)5 (42%)
HBO administered
 No, n (%)19 (19%)14 (16%)5 (42%)
 Yes, n (%)81 (81%)74 (84%)7 (58%)
DOI: https://doi.org/10.1515/raon-2016-0005 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Language: English
Page range: 94 - 100
Submitted on: Nov 27, 2015
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Accepted on: Jan 6, 2016
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Published on: Feb 7, 2016
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2016 Jasna Cotic, Jure Jamsek, Milan Kuhar, Natasa Ihan Hren, Andrej Kansky, Mutlu Özcan, Peter Jevnikar, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.