References
- Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011; 61: 69-90
- Winder T, Wilson PM, Yang D, Zhang W, Ning Y, Power DG, et al. An individual coding polymorphism and the haplotype of the SPARC gene predict gastric cancer recurrence. Pharmacogenomics J 2013; 13: 342-8
- Hudler P, Repse S, Juvan R, Komel R. A genomic approach to investigate expression profiles in Slovenian patients with gastric cancer. Oncol Lett 2011; 2: 1003-4
- Ottini L, Falchetti M, Lupi R, Rizzolo P, Agnese V, Colucci G, et al. Patterns of genomic instability in gastric cancer: clinical implications and perspectives. Ann Oncol 2006; 17: vii97-vii102
- Resende C, Ristimaki A, Machado JC. Genetic and epigenetic alteration in gastric carcinogenesis. Helicobacter 2010; 15(Suppl 1): 34-9
- Tahara E. Abnormal growth factor/cytokine network in gastric cancer. Cancer Microenviron 2008; 1: 85-91
- Chen J, Liu NN, Li JQ, Yang L, Zeng Y, Zhao XM, et al. Association between ITGA2 C807T polymorphism and gastric cancer risk. World J Gastroenterol2011; 17: 2860-6
- Gonzalez CA, Agudo A. Carcinogenesis, prevention and early detection of gastric cancer: where we are and where we should go. Int J Cancer 2012; 130: 745-53
- Milne AN, Carneiro F, O’Morain C, Offerhaus GJ. Nature meets nurture: molecular genetics of gastric cancer. Hum Genet 2009; 126: 615-28
- Pinheiro DdR, Ferreira WA, Barros MB, Araujo MD, Rodrigues-Antunes S, Borges Bdo N. Perspectives on new biomarkers in gastric cancer: diagnostic and prognostic applications. World J Gastroenterol 2014; 20: 11574-85
- Tan P. Germline polymorphisms as modulators of cancer phenotypes. BMC Med 2008; 6: 27
- Bass AJ, Thorsson V, Shmulevich I, Reynolds SM, Miller M, Bernard B, et al. Comprehensive molecular characterization of gastric adenocarcinoma. Nature 2014; 513: 202-9
- Grabsch HI, Askham JM, Morrison EE, Pomjanski N, Lickvers K, Parsons WJ, et al. Expression of BUB1 protein in gastric cancer correlates with the histological subtype, but not with DNA ploidy or microsatellite instability. J Pathol 2004; 202: 208-14
- Ando K, Kakeji Y, Kitao H, Iimori M, Zhao Y, Yoshida R, et al. High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer. Cancer Sci 2010; 101: 639-45
- Lo YL, Yu JC, Chen ST, Hsu GC, Mau YC, Yang SL, et al. Breast cancer risk associated with genotypic polymorphism of the mitotic checkpoint genes: a multigenic study on cancer susceptibility. Carcinogenesis 2007; 28: 1079-86
- Castro dIP, Carcer dG, Malumbres M. A census of mitotic cancer genes: New insights into tumor cell biology and cancer therapy. Carcinogenesis 2007; 28: 899-912
- Yuan B, Xu Y, Woo JH, Wang Y, Bae YK, Yoon DS, et al. Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability. Clin Cancer Res 2006; 12: 405-10
- Couch FJ, Wang X, Bamlet WR, de Andrade M, Petersen GM, McWilliams RR. Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome. Cancer Epidemiol Biomarkers Prev 2010; 19: 251-7
- Wang P, Wang Y, Yan H, Xie Q, Zhao L, Xu S, et al. Genetic variation in the major mitotic checkpoint genes and risk of breast cancer: a multigenic study on cancer susceptibility. Tumour Biol 2014; 35: 6701-5
- Wang X, Fredericksen ZS, Vierkant RA, Kosel ML, Pankratz VS, Cerhan JR, et al. Association of genetic variation in mitotic kinases with breast cancer risk. Breast Cancer Res Treat 2010; 119: 453-62
- Duesberg P, Rasnick D. Aneuploidy, the somatic mutation that makes cancer a species of its own. CellMotil Cytoskeleton 2000; 47: 81-107
- Frank SA. Genetic predisposition to cancer - insights from population genetics. Nat Rev Genet 2004; 5: 764-72
- Bolanos-Garcia VM, Lischetti T, Matak-Vinkovic D, Cota E, Simpson PJ, Chirgadze DY, et al. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding site. Structure 2011; 19: 1691-700
- Chao WC, Kulkarni K, Zhang Z, Kong EH, Barford D. Structure of the mitotic checkpoint complex. Nature 2012; 484: 208-13
- Tian W, Li B, Warrington R, Tomchick DR, Yu H, Luo X. Structural analysis of human Cdc20 supports multisite degron recognition by APC/C. Proc Natl Acad Sci U S A2012; 109: 18419-24
- Bolanos-Garcia VM, Blundell TL. BUB1 and BUBR1: multifaceted kinases of the cell cycle. Trends Biochem Sci 2011; 36: 141-50
- Kagami Y, Nihira K, Wada S, Ono M, Honda M, Yoshida K. Mps1 phosphorylation of condensin II controls chromosome condensation at the onset of mitosis. J Cell Biol 2014; 205: 781-90
- Santaguida S, Tighe A, D’Alise AM, Taylor SS, Musacchio A. Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine. J Cell Biol 2010; 190: 73-87
- Lee S, Thebault P, Freschi L, Beaufils S, Blundell TL, Landry CR, et al. Characterization of spindle checkpoint kinase Mps1 reveals domain with functional and structural similarities to tetratricopeptide repeat motifs of Bub1 and BubR1 checkpoint kinases. J Biol Chem 2012; 287: 5988-6001
- Hewitt L, Tighe A, Santaguida S, White AM, Jones CD, Musacchio A, et al. Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex. J Cell Biol 2010; 190: 25-34
- Rodriguez S, Gaunt TR, Day IN. Hardy-Weinberg equilibrium testing of biological ascertainment for Mendelian randomization studies. Am J Epidemiol2009; 169: 505-14
- Farre D, Roset R, Huerta M, Adsuara JE, Rosello L, Alba MM, et al. Identification of patterns in biological sequences at the ALGGEN server: PROMO and MALGEN. Nucleic Acids Res 2003; 31: 3651-3
- Messeguer X, Escudero R, Farre D, Nunez O, Martinez J, Alba MM. PROMO: detection of known transcription regulatory elements using species-tailored searches. Bioinformatics 2002; 18: 333-4
- Abecasis GR, Auton A, Brooks LD, DePristo MA, Durbin RM, Handsaker RE, et al. An integrated map of genetic variation from 1,092 human genomes. Nature 2012; 491: 56-65
- Cui Y, Cheng X, Zhang C, Zhang Y, Li S, Wang C, et al. Degradation of the human mitotic checkpoint kinase Mps1 is cell cycle-regulated by APC-cCdc20 and APC-cCdh1 ubiquitin ligases. J Biol Chem 2010; 285: 32988-98
- Sun T, Yang X, Wang W, Zhang X, Xu Q, Zhu S, et al. Cellular abundance of Mps1 and the role of its carboxyl terminal tail in substrate recruitment. J Biol Chem 2010; 285: 38730-9
- Kaistha BP, Honstein T, Muller V, Bielak S, Sauer M, Kreider R, et al. Key role of dual specificity kinase TTK in proliferation and survival of pancreatic cancer cells. Br J Cancer 2014; 111: 1780-7
- Ling Y, Zhang X, Bai Y, Li P, Wei C, Song T, et al. Overexpression of Mps1 in colon cancer cells attenuates the spindle assembly checkpoint and increases aneuploidy. Biochem Biophys Res Commun 2014; 450: 1690-5
- Rio Frio T, Lavoie J, Hamel N, Geyer FC, Kushner YB, Novak DJ, et al. Homozygous BUB1B mutation and susceptibility to gastrointestinal neoplasia. N Engl J Med 2010; 363: 2628-37
- Grabsch H, Takeno S, Parsons WJ, Pomjanski N, Boecking A, Gabbert HE, et al. Overexpression of the mitotic checkpoint genes BUB1, BUBR1, and BUB3 in gastric cancer--association with tumour cell proliferation. J Pathol 2003; 200: 16-22
- Enjoji M, lida S, Sugita H, Ishikawa T, Uetake H, Inokuchi M, et al. BubR1 and AURKB overexpression are associated with a favorable prognosis in gastric cancer. Mol Med Report 2009; 2: 589-96
- Bohers E, Sarafan-Vasseur N, Drouet A, Paresy M, Latouche JB, Flaman JM, et al. Gradual reduction of BUBR1 protein levels results in premature sister-chromatid separation then in aneuploidy. Hum Genet 2008; 124: 473-8
- D’Arcy S, Davies OR, Blundell TL, Bolanos-Garcia VM. Defining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibition. J Biol Chem 2010; 285: 14764-76