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Cerebral toxoplasmosis in a diffuse large B cell lymphoma patient

Radiology and Oncology
Volume 50 (2016): Issue 1 (March 2016)
By:
Open Access
|Feb 2016

Figures & Tables

Figure 1.

(A) MRI at time of diagnosis demonstrating multiple T2 and (B) fluid attenuated inversion recovery (FLAIR) hyperintense parenchymal lesions, located in both cerebral and cerebellar hemispheres, with mild surrounding edema. (C) On T1 sequences, these lesions were hypointense. (D) After contrast administration, only moderate rim enhancement was seen.
(A) MRI at time of diagnosis demonstrating multiple T2 and (B) fluid attenuated inversion recovery (FLAIR) hyperintense parenchymal lesions, located in both cerebral and cerebellar hemispheres, with mild surrounding edema. (C) On T1 sequences, these lesions were hypointense. (D) After contrast administration, only moderate rim enhancement was seen.

Figure 2.

Full body 18F-FDG PET/CT revealing focal hypometabolism, corresponding to toxoplasma lesions. The largest lesion is seen in the right occipital lobe.
Full body 18F-FDG PET/CT revealing focal hypometabolism, corresponding to toxoplasma lesions. The largest lesion is seen in the right occipital lobe.

Figure 3.

Lesion size and edema reduction after 6 weeks of intensive antibiotic therapy, as demonstrated by (A) fluid attenuated inversion recovery (FLAIR) and (B) T1 sequence.
Lesion size and edema reduction after 6 weeks of intensive antibiotic therapy, as demonstrated by (A) fluid attenuated inversion recovery (FLAIR) and (B) T1 sequence.

Figure 4.

Follow-up MRI after 4 months reveals further reduction of lesion size. (A) T1 sequence + gadolinium, (B) T2 sequence.
Follow-up MRI after 4 months reveals further reduction of lesion size. (A) T1 sequence + gadolinium, (B) T2 sequence.
DOI: https://doi.org/10.1515/raon-2014-0042 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
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Language: English
Page range: 87 - 93
Submitted on: May 27, 2014
Accepted on: Aug 21, 2014
Published on: Feb 16, 2016
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
toxoplasmosis,
cerebral,
lymphoma, B-cell,
rituximab,
hosts, immunocompromised,
magnetic resonance imaging,
treatment
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Haematology, oncology,
Radiology

© 2016 Lina Savsek, Tanja Ros Opaskar, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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