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Visualisation of Microglia with the use of Immunohistochemical Double Staining Method for CD-68 and Iba-1 of Cerebral Tissue Samples in Cases of Brain Contusions Cover

Visualisation of Microglia with the use of Immunohistochemical Double Staining Method for CD-68 and Iba-1 of Cerebral Tissue Samples in Cases of Brain Contusions

PRILOZI
Volume 36 (2015): Issue 2 (December 2015)
By: ,  ,  ,  ,   and    
Open Access
|Dec 2015
References

References

  1. 1. Perry VH, Andersson PB, Gordon S. Macrophages and inflammation in the central nervous system. Trends Neurosci. 1993; 16: 268-273.
    Open DOISearch in Google Scholar
  2. 2. Perry VH, Gordon S. Microglia and macrophages In Immunology of the nervous system: Keane RW, Hickey WF (eds). Oxford University Press, New York, 1997; pp 155−182.
    Search in Google Scholar
  3. 3. Somjen GG. Notes on the history of the concept of neuroglia. Glia.1988; 1: 2-9.
    Open DOISearch in Google Scholar
  4. 4. Streit WJ, Kincaid-Colton CA. The brain’s immune system. Sci Am. 1995; 273: 54-61.
    Open DOISearch in Google Scholar
  5. 5. Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 1996; 19(8): 312-318.
    Open DOISearch in Google Scholar
  6. 6. Oehmichen M. Functional properties of microglia. In Recent advances in neuropathology, vol. 2. Smith WT, Cavanagh JB, eds. Churchill Livingstone, Edinburgh, London, New York. 1982; pp 83-107.
    Search in Google Scholar
  7. 7. Oehmichen M. Cytokinetic studies on the origin of the cells of the cerebrospinal fluid. J Neurol Sci. 1974; 22: 165-176.
    Open DOISearch in Google Scholar
  8. 8. Ling EA, Wong WC. The origin and nature of ramified and amoeboid microglia: a historical review and current concepts. Glia. 1993; 7: 9−18.
    Open DOISearch in Google Scholar
  9. 9. Nimmerjahn A, Kirchhoff F, Helmchen F. Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo. Science. 2005; [308]5726: 1314-1318.
    Open DOISearch in Google Scholar
  10. 10. Hanisch UK, Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci. 2007 Nov; 10[11]: 1387-94. http://dx.doi.org/10.1155/2013/205431
    Open DOISearch in Google Scholar
  11. 11. Imai Y, Ibata I, Ito D, Ohsawa K, Kohsaka S. A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage. Biochem. Biophys. Res. Commun. 1996; 224: 855-862.
    Search in Google Scholar
  12. 12. Ito D, Imai Y, Ohsawa K, Nakajima K, Fukuuchi Y, Kohsaka S. Microglia-specific localisation of a novel calcium binding protein, Iba1. Brain Res. Mol. Brain Res. 1998; 57: 1-9.
    Search in Google Scholar
  13. 13. Ito D, Tanaka K, Suzuki S, Dembo T, Fukuuchi Y. Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain. Stroke. 2001; 32: 1208-1215.
    Open DOISearch in Google Scholar
  14. 14. Mori I, Imai Y, Kohsaka S, Kimura Y. Upregulated expression of. Iba1 molecules in the central nervous system of mice in response to neurovirulent influenza A virus infection.Microbiol. Immunol. 2000; 44: 729-735.
    Search in Google Scholar
  15. 15. von Ertzen. U, Egensperger R, Kosel S, Grasbon-Frodal EM, Imai Y, Bise K, et al. Microglia and the development of spongiform change in Creutzfeldt-Jakob disease. J Neuropathol. Exp. Neurol. 1998; 57: 246-256.
    Search in Google Scholar
  16. 16. Ohsawa K, Imai Y, Kanazawa H, Sasaki Y, Kohsaka S. Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia. J. Cell Sci. 2000; 113: 3073-3084.
    Open DOISearch in Google Scholar
  17. 17. Ridley AJ, Paterson HF, Johnston CL, Diekmann D, Hall A. The small GTP-binding protein rac regulates growth factorinduced membrane ruffling. Cell. 1992; 70: 401-410.
    Open DOISearch in Google Scholar
  18. 18. Hall A. Rho GTPases and the actin cytoskeleton. Science. 1998; 279: 509-514.
    Open DOISearch in Google Scholar
  19. 19. Allen WE, Jones GE, Pollard JW, Ridley AJ. Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages. J. Cell Sci. 1997; 110: 707-720.
    Open DOISearch in Google Scholar
  20. 20. Graeber MB, Streit WJ, Kiefer R, Schoen SW, Kreutzberg GW. New expression of myelomonocytic antigens by microglia and perivascular cells following lethal motor neurone injury. J. Neuroimmunol. 1990; 27: 121-131.
    Open DOISearch in Google Scholar
  21. 21. Slepko N, Levi G. Progressive activation of adult microglial cells in vitro. Glia 1996; 16: 241-246.
    Open DOISearch in Google Scholar
  22. 22. Kingham PJ, Cuzner ML, Pocock JM. Apoptotic pathways mobilized in microglia and neurones as a consequence of chromogranin A-induced microglial activation. J. Neurochem. 1999; 73: 538-547.
    Open DOISearch in Google Scholar
  23. 23. Schnieder TP, Trencevska I, Rosoklija G, Stankov A, Mann JJ, Smiley J, Dwork AJ. Microglia of prefrontal white matter in suicide. J Neuropathol Exp Neurol. 2014 Sep; 73(9): 880-90.
    Open DOISearch in Google Scholar
  24. 24. Gehrmann J, Kreutzberg GW. Characterisation of two new mono-clonal antibodies directed against rat microglia, J. Comp. Neurol. 1991; 313: 409-430.
    Search in Google Scholar
  25. 25. Graeber MB, Streit WJ, Kreutzberg GW. Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells, J. Neurosci. Res. 1988; 211: 8-24.
    Search in Google Scholar
  26. 26. Graeber MB, Streit WJ, Kreutzberg GW. Identity of ED2-positive perivascular cells in rat brain, J. Neurosci. Res. 1989; 22: 103-106.
    Search in Google Scholar
  27. 27. Lawson LJ, Perry VH, Dri P, Gordon S. Heterogeneity in the distribution and morphology of microglia in the normal, adult mouse brain, Neuroscience. 1990; 39: 151-170.
    Search in Google Scholar
  28. 28. Perry VH, Hume DA, Gordon S. Immunohistochemical localisation of macrophages and microglia in the adult and developing mouse brain, Neuroscience. 1985; 15: 313-326.
    Search in Google Scholar
  29. 29. Thomas WE. Brain macrophages: evaluation of microglia and their functions, Brain Res. Rev. 1992; 17: 61-74.
    Search in Google Scholar
  30. 30. Ito D1, Imai Y, Ohsawa K, Nakajima K, Fukuuchi Y, Kohsaka S. Microglia-specific localisation of a novel calcium binding protein, Iba1Brain Res Mol Brain Res. 1998; 57[1]: 1-9.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.1515/prilozi-2015-0062 | Journal eISSN: 1857-8985 (formerly 0350-1914) | Journal ISSN: 1857-9345
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Language: English, Russian
Page range: 141 - 145
Published on: Dec 30, 2015
Published by: Macedonian Academy of Sciences and Arts
In partnership with: Paradigm Publishing Services
Publication frequency: 3 issues per year
Keywords:
microglia cells,
immunohistochemistry,
brain contusions
Related subjects:
Social sciences,
Education,
Education, other

© 2015 Aleksandar Stankov, Viktorija Belakaposka-Srpanova, Natasa Bitoljanu, Ljupco Cakar, Zdravko Cakar, Gorazd Rosoklija, published by Macedonian Academy of Sciences and Arts
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 36 (2015): Issue 2 (December 2015)
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