Original Research. Transluminal Contrast Attenuation Gradient Is Associated with Coronary Plaque Vulnerability — a Computed Tomography Angiography-based Study

Orzan, Marius; Hodas, Roxana; Dobra, Mihaela; Rat, Nora; Chitu, Monica; Benedek, Imre

Original Research. Transluminal Contrast Attenuation Gradient Is Associated with Coronary Plaque Vulnerability — a Computed Tomography Angiography-based Study

Journal of Cardiovascular Emergencies

Volume 3 (2017): Issue 3 (September 2017)

By:

Marius Orzan, Roxana Hodas, Mihaela Dobra, Nora Rat, Monica Chitu and Imre Benedek

Open Access

|Oct 2017

References

1. Dubey G, Verma SK, Bahl VK. Primary percutaneous coronary intervention for acute ST elevation myocardial infarction: Outcomes and determinants of outcomes: A tertiary care center study from North India. Indian Heart J. 2017;69:294-298. doi: 10.1016/j.ihj.2016.11.322.
Open DOI Search in Google Scholar Back to article
2. Barton GR, Irvine L, Flather M, et al. Economic Evaluation of Complete Revascularization for Patients with Multivessel Disease Undergoing Primary Percutaneous Coronary Intervention. Value Health. 2017;20:745-751. doi: 10.1016/j.jval.2017.02.002.
Open DOI Search in Google Scholar Back to article
3. Roffi M, Patrono C, Collet JP, et al. ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J 2015; 37:267-315. doi: 10.1093/eurheartj/ehv320.
Open DOI Search in Google Scholar Back to article
4. Benedek T. The Hemodynamic Impact of Unstable Coronary Plaques - Do We Have the Evidence? Jornal of Cardiovascular Emergencies. 2017;3:59-60. doi: 10.1515/jce-2017-0014.
Open DOI Search in Google Scholar Back to article
5. Kwon JE, Lee WS, Mintz GS, et al. Multimodality Intravascular Imaging Assessment of Plaque Erosion versus Plaque Rupture in Patients with Acute Coronary Syndrome. Korean Circ J. 2016;46:499-506. doi: 10.4070/kcj.2016.46.4.499.
Open DOI Search in Google Scholar Back to article
6. Tonino PA, Fearon WF, De Bruyne B, et al. Angiographic versus functional severity of coronary artery stenoses in the FAME study fractional flow reserve versus angiography in multivessel evaluation. J Am Coll Cardiol. 2010;55:2816-2821. doi: 10.1016/j.jacc.2009.11.096.
Open DOI Search in Google Scholar Back to article
7. De Bruyne B, Pijls NH, Kalesan B, et al. Fractional flow reserveguided PCI versus medical therapy in stable coronary disease. N Engl J Med. 2012;367:1768. doi: 10.1056/NEJMoa1205361.
Open DOI Search in Google Scholar Back to article
8. Mollet N, Maffei E, Martini C, et al. Coronary plaque burden in patients with stable and unstable coronary artery disease using multislice CT coronary angiography. Radiol Med. 2011;116:1174-1187. doi: 10.1007/s11547-011-0722-5.
Open DOI Search in Google Scholar Back to article
9. Dalager MG, Bøttcher M, Thygesen J, et al. Different Plaque Composition and Progression in Patients with Stable and Unstable Coronary Syndromes Evaluated by Cardiac CT. Biomed Res Int. 2015:401357. doi: 10.1155/2015/401357.
Open DOI Search in Google Scholar Back to article
10. Tesche C, De Cecco CN, Caruso D, et al. Coronary CT angiography derived morphological and functional quantitative plaque markers correlated with invasive fractional flow reserve for detecting hemodynamically significant stenosis. J Cardiovasc Comput Tomogr. 2016;10:199-206. doi: 10.1155/2015/401357.
Open DOI Search in Google Scholar Back to article
11. De Cecco CN, Caruso D, Baumann S, et al. Coronary CT angiography derived morphological and functional quantitative plaque markers correlated with invasive fractional flow reserve for detecting hemodynamically significant stenosis. J Cardiovasc Comput Tomogr. 2016;10:199-206. doi: 10.1016/j.jcct.2016.03.002.
Open DOI Search in Google Scholar Back to article
12. Orzan M, Dobra M, Chitu M. A Comparative Preliminary Study on CT Contrast Attenuation Gradient Versus Invasive FFR in Patients with Unstable Angina. Journal of cardiovascular emergencies. 2017;3:72-78. doi: 10.1515/jce-2017-0012.
Open DOI Search in Google Scholar Back to article
13. Dong L, Mintz GS, Witzenbichler B, et al. Comparison of plaque characteristics in narrowings with ST-elevation myocardial infarction (STEMI), non-STEMI/unstable angina pectoris and stable coronary artery disease (from the ADAPT-DES IVUS Substudy). Am J Cardiol. 2015;115:860-866. doi: 10.1016/j.amjcard.2015.01.008.
Open DOI Search in Google Scholar Back to article
14. Andreini D, Pontone G, Mushtaq S, et al. A long-term prognostic value of coronary CT angiography in suspected coronary artery disease. JACC Cardiovasc Imaging. 2012;5:690-701. doi: 10.1016/j.jcmg.2012.03.009.
Open DOI Search in Google Scholar Back to article
15. Cademartiri F, Seitun S, Clemente A, et al. Myocardial blood flow quantification for evaluation of coronary artery disease by computed tomography. Cardiovase Diagn Ther. 2017;7:129-150. doi: 10.21037/cdt.2017.03.22.
Open DOI Search in Google Scholar Back to article
16. Peng K, Xu N, Zhang L, et al. Transluminal attenuation gradient and corrected models in coronary CT angiography for determining stenosis severity: a primary study using dual-source CT. Clin Radiol. 2017;72:508-516. doi: 10.1016/j.crad.2017.01.003.
Open DOI Search in Google Scholar Back to article
17. Kim HJ, Kim SM, Choi JH, et al. Influence of scan technique on intracoronary transluminal attenuation gradient in coronary CT angiography using 128-slice dual source CT: multi-beat versus one-beat scan. Int J Cardiovasc Imaging. 2017;33:937-946. doi: 10.1007/s10554-017-1078-2.
Open DOI Search in Google Scholar Back to article
18. Benz DC, Mikulicic F, Gräni C, et al. Long-term outcome prediction by functional parameters derived from coronary computed tomography angiography. Int J Cardiol. 2017; 243:533-537. doi: 10.1016/j.ijcard.2017.05.083.
Open DOI Search in Google Scholar Back to article
19. Boden WE, O'Rourke RA, Teo KK, et al. Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med. 2007;356:1503-1516. doi: 10.1056/NEJMoa070829.
Open DOI Search in Google Scholar Back to article
20. Choi JH, Min JK, Labounty TM, et al. Intracoronary transluminal attenuation gradient in coronary CT angiography for determining coronary artery stenosis. JACC Cardiovasc Imaging. 2011;4:1149-1157. doi: 10.1016/j.jcmg.2011.09.006.
Open DOI Search in Google Scholar Back to article
21. Benedek I, Bucur O, Benedek T. Intracoronary infusion of mononuclear bone marrow-derived stem cells is associated with a lower plaque burden after four years. J Atheroscler Thromb. 2014;21:217-229.10.5551/jat.19745
Open DOI Search in Google Scholar Back to article
22. Benedek T, Gyöngyösi M, Benedek I, et al. Multislice computed tomographic coronary angiography for quantitative ssessment of culprit lesions in acute coronary syndromes. Can J Cardiol. 2013;29:364-371. doi: 10.1016/j.cjca.2012.11.004.
Open DOI Search in Google Scholar Back to article
23. Chow BJ, Kass M, Gagné O, et al. Can differences in corrected coronary opacification measured with computed tomography predict resting coronary artery flow? J Am Coll Cardiol. 2011;57:1280-1288. doi: 10.1016/j.jacc.2010.09.072.
Open DOI Search in Google Scholar Back to article
24. Benedek T, Jako B, Benedek I. Plaque quantification by coronary CT and intravascular ultrasound identifies a low CT density core as a marker of plaque instability in acute coronary syndromes. Int Heart J. 2014;55:22-28.10.1536/ihj.13-213
Open DOI Search in Google Scholar Back to article

DOI: https://doi.org/10.1515/jce-2017-0016 | Journal eISSN: 2457-5518 | Journal ISSN: 2457-550X

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Language: English

Page range: 121 - 127

Submitted on: Jul 17, 2017

Accepted on: Sep 10, 2017

Published on: Oct 25, 2017

Published by: Asociatia Transilvana de Terapie Transvasculara si Transplant KARDIOMED

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

contrast attenuation,

computed tomography angiography,

coronary artery disease,

fractional flow reserve,

vulnerable coronary plaque

Related subjects:

Emergency medicine and intensive-care medicine,

Radiology

© 2017 Marius Orzan, Roxana Hodas, Mihaela Dobra, Nora Rat, Monica Chitu, Imre Benedek, published by Asociatia Transilvana de Terapie Transvasculara si Transplant KARDIOMED
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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