Detection of Myocardial Injury Using miRNAs Expression as Genetic Biomarkers in Acute Cardiac Care

Alexandru Florin Rogobete; Ovidiu Horea Bedreag; Sonia Elena Popovici; Adriana Mariana Sas; Adrian Tudor Stan; Emil Robert Stoicescu; Dorel Sandesc

doi:10.1515/jce-2016-0025

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Detection of Myocardial Injury Using miRNAs Expression as Genetic Biomarkers in Acute Cardiac Care

Journal of Cardiovascular Emergencies

Volume 2 (2016): Issue 4 (December 2016)

By: Alexandru Florin Rogobete, Ovidiu Horea Bedreag, Sonia Elena Popovici, Adriana Mariana Sas, Adrian Tudor Stan, Emil Robert Stoicescu and Dorel Sandesc

Open Access

|Dec 2016

Abstract

Cardiovascular disease is a leading cause of death globally. At present, there are many ways to diagnose this pathophysiology. The greatest disadvantages related to current biomarkers are their low specificity, low selectivity and low accuracy. A new method, extensively studied recently, is the expression of miRNAs, used as genetic biomarkers for the early diagnosis of cardiovascular diseases. This paper presents an update of miRNAs species expression that can serve as early diagnostic biomarkers and for the continuous monitoring of patients with cardiovascular disease.

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Articles in this issue

DOI: https://doi.org/10.1515/jce-2016-0025 | Journal eISSN: 2457-5518 | Journal ISSN: 2457-550X

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Language: English

Page range: 169 - 172

Submitted on: Sep 10, 2016

Accepted on: Oct 15, 2016

Published on: Dec 30, 2016

Published by: Asociatia Transilvana de Terapie Transvasculara si Transplant KARDIOMED

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

microRNA,

acute myocardial infarction,

Related subjects:

Emergency medicine and intensive-care medicine,

Radiology

© 2016 Alexandru Florin Rogobete, Ovidiu Horea Bedreag, Sonia Elena Popovici, Adriana Mariana Sas, Adrian Tudor Stan, Emil Robert Stoicescu, Dorel Sandesc, published by Asociatia Transilvana de Terapie Transvasculara si Transplant KARDIOMED
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 2 (2016): Issue 4 (December 2016)