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Comparative effects of meso-2,3-dimercaptosuccinic acid, monensin, and salinomycin on cadmium-induced brain dysfunction in cadmium-intoxicated mice Cover

Comparative effects of meso-2,3-dimercaptosuccinic acid, monensin, and salinomycin on cadmium-induced brain dysfunction in cadmium-intoxicated mice

Open Access
|Feb 2018

References

  1. Afifi OK, Embaby AS. (2016). Histological Study on the Protective Role of Ascorbic Acid on Cadmium Induced Cerebral Cortical Neurotoxicity in Adult Male Albino Rats. Journal of Microscopy and Ultrastructure4(1): 36–45.
  2. Antoszczak M, Huczyński A. (2015). Anticancer Activity of Polyether Ionophore-Salinomycin. Anticancer Agents Med Chem15(5): 575–91.
  3. Ayannuga OA, Oyekunle JA, Ijomone OM, Ibeachusim BI. (2015). Cadmium and Lead Toxicity, Modulating Roles of Age and Trace Metals on Wistar Rat Cortical Cells. Environ Pollut4(3): 51–61.
  4. Bernhoft RA. (2013). Cadmium Toxicity and Treatment. Scientific World J. 2013: Article ID 394652.
  5. Blaurock-Busch E, Busch YM. (2014). Comparison of Chelating Agents DMPS, DMSA and EDTA for the Diagnosis and Treatment of Chronic Metal Exposure. Br J Med Med Res4(9): 1821–1835.
  6. Boehmerle W, Muenzfeld H, Springer A, Huehnchen P, Endres M. (2014). Specific targeting of neurotoxic side effects and pharmacological profile of the novel cancer stem cell drug salinomycin in mice. J Mol Med 92: 889–900.10.1007/s00109-014-1155-0
  7. Cuajungco MP, Faget KY. (2003). Zinc takes the center stage: its paradoxical role in Alzheimer’s disease. Brain Res Brain Res Rev41(1): 44–56.10.1016/S0165-0173(02)00219-9
  8. Desai V, Kaler SG. (2008). Role of copper in human neurological disorders. Am J Clin Nutr88(3): 855S–8S.
  9. Flora SJ, Pachauri V. (2010). Chelation in Metal Intoxication. Int J Environ Res Public Health7: 2745–2788.
  10. Gale GR, Atkins LM, Walker EM, Smith AB. (1983). Comparative effects of diethyldithiocarbamate, dimercaptosuccinate, and diethylenetriaminepentaacetate on organ distribution and excretion of cadmium. Ann Clin Lab Sci13(1): 33–43.
  11. Gegova A, Mitkov D, Gluhcheva Y, Arpadjan S, Mitewa M, Ivanova Ju. (2012). Effects of cadmium and monensin on the morphology of lung of mice, subjected to subacute cadmium intoxication. Acta Morphol et Anthropol19: 47–52.
  12. Gertenbach PG, Popov Al. (1975). Solution chemistry of monensin and its alkali metal ion complexes. Potentiometric and spectroscopic studies. J Am Chem Soc97: 4738–44.10.1021/ja00849a041
  13. Gluhcheva Y, Ivanova Ju, Ganeva S, Mitewa M. (2013). Effects of cadmium and monensin on spleen of mice, subjected to subacute cadmium intoxication. J Toxicol Environ Health - Part A: Current Issues76(4–5): 328–332.
  14. Goncёalves JF, Fiorenza AM, Spanevello RM. (2010). N-acetylcysteine prevents memory deficits, the decrease in acetylcholinesterase activity and oxidative stress in rats exposed to cadmium. Chem-Bioll Interact186(1): 53–60.
  15. Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser Ch, Weinberg RA, Lander ES. (2009). Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell138(4): 645–659.
  16. Haider S, Anis L, Batool Z, Sajid I, Naqvi F, Khaliq S, Ahmed S. (2015). Short term cadmium administration dose dependently elicits immediate biochemical, neurochemical and neurobehavioral dysfunction in male rats. Metab Brain Dis30(1): 83–92.
  17. Ivanova Ju, Pantcheva I, Mitewa M, Mayer-Figge H, Simova S, Shieldrick SW. (2010). Crystal structure and spectral properties of new Cd(II) and Hg(II) complexes of monensic acid with different coordination mode of ligand. Cent Eur J Chem8(4): 852–60.
  18. Ivanova Ju, Gluhcheva Y, Kamenova, K, Arpadjan S, Mitewa M. (2012a). The tetraethylammonium salt of monensic acid-An antidote for subacute cadmium intoxication: a study using an ICR mouse model. J Trace Elem Med Biol26: 279–84.10.1016/j.jtemb.2012.02.00322677540
  19. Ivanova Ju, Pantcheva IN, Zhorova R, Momekov G, Simova S, Stoyanova R, Zhecheva E, Ivanova S, Mitewa M. (2012b). Synthesis, spectral properties, antibacterial and antitumor activity of Salinomycin complexes with Co(II), Ni(II), Cu(II) and Zn(II) transition metal ions. J Chem Chem Eng6: 51–562.
  20. Ivanova Ju, Gluhcheva Y, Arpadjan S, Mitewa M. (2014a). Effect of cadmium and monensin on renal and cardiac function of mice, subjected to sub-acute cadmium intoxication. Interdiscip Toxicol7(2): 111–115.10.2478/intox-2014-0015442772326109887
  21. Ivanova Ju, Gluhcheva Y, Kamenova K, Arpadjan S, Mitewa M. (2014b). Monensin ameliorates Cd-induced hepatic injury in mice, subjected to subacute Cd intoxication. Biotechnol Biotechnol Eq28(1): 147–152.10.1080/13102818.2014.901673468404226740751
  22. Johnson S. (2001). Gradual micronutrient accumulation and depletion in Alzheimer’s disease. Med. Hypotheses56(6): 595–597.10.1054/mehy.2000.130111399105
  23. Jomova K, Vondrakova D, Lawson M, Valko M. (2010). Metals, oxidative stress and neurodegenerative disorders. Mol Cell Biochem45(1–2): 91–104.
  24. Kaoud H, Mekawy M. (2011). Effect of Cadmium Pollution on Neuromorphology and Function of brain in Mice Offspring. Nature and Science9(4): 28–35.
  25. Kart A, Bilgili A. (2008). Ionophore antibiotics: toxicity, mode of action, and neurotoxic aspects of carboxylic ionophores. J Animal Vet Adv7(6): 748–751.
  26. Kevin Ii DA, Meujo DA, Hamann MT. (2016). Polyether ionophores: broad-spectrum and promising biologically active molecules for the control of drug-resistant bacteria and parasites. Expert Opin Drug Discov4(2): 109–46.
  27. Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG. (2010). Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research. PLoS Biol8(6): e1000412.
  28. Maodaa SN, Allam AA, Ajarem J, Abdel-Maksoud MA, Al-Basher GI, Wang ZY. (2016). Effect of parsley (Petroselinum crispum, Apiaceae) juice against cadmium neurotoxicity in albino mice (Mus Musculus). Behav Brain Funct12(1): 6.10.1186/s12993-016-0090-3474336226846273
  29. Mascagni P. Consonni D, Bregante G, Chiappino G, Toffoletto F. (2003). Olfac-tory function in workers exposed to moderate airborne cadmium levels. Neuro Toxicol24(4–5): 717–724.
  30. Mendez-Armenta M, Rios C. (2007). Cadmium neurotoxicity. Environ Toxicol Pharmacol23(3): 350–358.10.1016/j.etap.2006.11.00921783780
  31. Min JI, Min KB. (2016). Blood cadmium levels and Alzheimer‘s disease mortality risk in older US adults. Environ Health15(1): 69–74.10.1186/s12940-016-0155-7490872527301955
  32. Naujokat C, Steinhart R. (2012). Salinomycin as a Drug for Targeting Human Cancer Stem Cells. J Biomed Biotechnol2012: Article ID 950658.
  33. Okuda B, Iwamoto Y, Tachibana H, Sugita M. (1997). Parkinsonism after acute cadmium poisoning. Clin Neurol Neurosurg99(4): 263–265.
  34. Panayi AE, Spyrou NM, Iversen BS, White MA, Part P. (2002). Determination of cadmium and zinc in Alzheimer’s brain tissue using Inductively Coupled Plasma Mass Spectrometry. J Neurol Sci195(1): 1–10.
  35. Pavlova E, Ivanova Ju, Dimova D, Gluhcheva Y, Atanassova N. (2012). Alterations in adult mouse testis after subacute intoxication with cadmium and monensin detoxication. Eur Chem Bull1: 463–465.
  36. Prozialeck WC, Edwards JR, Woods JM. (2006). The vascular endothelium as a target of cadmium toxicity. Life sciences79(16): 1493–1506.10.1016/j.lfs.2006.05.007
  37. Rinaldi M, Micali A, Marini H, Adamo EB, Puzzolo D, Pisani A, Trichilo V, Alta-villa D, Squadrito F, Minutoli L. (2017). Cadmium, organ toxicity and therapeutic approaches. A review on brain, kidney and testis damage. Curr Med Chem, in press10.2174/0929867324666170801101448
  38. Salvador GA, Uranga RM, Giusto NM. (2011). Iron and mechanisms of neurotoxicity. Int J Alzheimers Dis2010: 720658.
  39. Sarić MM, Blanusa M, Juresa D, Sarić M, Varnai VM, Kostial K. (2004). Combined early treatment with chelating agents DMSA and CaDTPA in acute oral cadmium exposure. Basic Clin Pharmacol Toxicol94(3): 119–23.10.1111/j.1742-7843.2004.pto940304.x
  40. Satarug S, Garrett SH, Sens MA, Sens DA. (2010). Cadmium, environmental exposure, and health outcomes. Environ Health Perspect118(2): 182–90.
  41. Strausak D, Mercer JF, Dieter HH, Stremmel W, Multhaup G. (2001). Copper in disorders with neurological symptoms: Alzheimer’s, Menkes, and Wilson diseases. Brain Res Bull55(2): 175–85.10.1016/S0361-9230(01)00454-3
  42. Syed SH. (2016). Effects of Cadmium Toxicity on Bio-distribution of Trace Elements in Normal and Protein Malnourished Rats. Int J Cell Sci & Mol Biol1(1): 555553.
  43. Valensin D, Padula EM, Hecel A, Luczkowski M, Kozlowski H. (2016). Specific binding modes of Cu(I) and Ag(I) with neurotoxic domain of the human prion protein. J Inorg. Biochem.155: 26–35.
  44. Vukićević T. (2012). Toxic effects of cadmium. Acta med. Mediterr. 51(4): 65–70.
  45. Wang B, Du Y. (2013). Cadmium and Its Neurotoxic Effects. Oxid Med Cell Longev2013: Article ID 898034.
  46. Wang H, Zhang L, Abel GM, Storm DR, Xia Z. (2017) Cadmium exposure impairs cognition and olfactory memory in male C57BL/6 mice. Toxicol Sci [in press].10.1093/toxsci/kfx202583736129029324
  47. Xu B, Chen S, Luo Y, Chen Zi, Liu L, Zhou H, Chen W, Shen T, Han X, Chen L, Huang S. (2011). Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network. PloS One6(4): Article ID e19052.
  48. Yang XF, Fan GY, Liu DY, Zhang HT, Xu ZY, Ge YM, Wang ZL. (2015). Effect of Cadmium Exposure on the Histopathology of Cerebral Cortex in Juvenile Mice. Biol Trace Elem Res165: 167–172.
  49. Yuan Y, Jiang C-Y, Xu XH, Sun Y, Hu FF, Bian JC, Liu XZ, Gu JH, Liu ZF. (2013). Cadmium-induced apoptosis in primary rat cerebral cortical neurons culture is mediated by a calcium signaling pathway. PLoS One8(5): Article ID e64330.
  50. Zucca FA, Segura-Aguilar J, Ferrari E, Muñoz EP, Paris I, Sulzer D, Sarna Casella TL, Zecca L. (2017). Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson’s disease. Prog Neurobiol155: 96–119.
DOI: https://doi.org/10.1515/intox-2017-0017 | Journal eISSN: 1337-9569 | Journal ISSN: 1337-6853
Language: English
Page range: 107 - 113
Submitted on: Mar 27, 2017
Accepted on: Nov 28, 2017
Published on: Feb 14, 2018
Published by: Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2018 Juliana Ivanova, Emilia Petrova, Kalina Kamenova, Yordanka Gluhcheva, published by Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.