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Neonicotinoids and their Metabolites in Human Biomonitoring: A Review Cover

Neonicotinoids and their Metabolites in Human Biomonitoring: A Review

Hellenic Plant Protection Journal
Volume 8 (2015): Issue 2 (July 2015)
By:  and    
Open Access
|Jul 2015
References

References

  1. Benotti, M.J., Trenholm, R.A., Vanderford, B.J., Holady, J.C., Stanford, B.D. and Snyder, S.A. 2009. Pharmaceuticals and endocrine disrupting compounds in U.S. drinking water. Environmental Science & Technology, 43: 597-603.
    Search in Google Scholar
  2. Bioanalytical-Validation, Guidance for Industry: Bioanalytical Method Validation. http://www.fda.gov/downloads/Drugs/Guidances/ucm070107.pdf, accessed at 25-05-2015.
    Search in Google Scholar
  3. Bosch-Ojeda, C. and Sanchez-Rojas, F. 2009. Separation and Preconcentration by Dispersive Liquid- Liquid Microextraction Procedure: A Review. Chromatographia, 69: 1-11.
    Open DOISearch in Google Scholar
  4. Bouchard, M.F., Chevrier, J., Harley, K.G., Kogut, K., Vedar, M., Calderon, N., Trujillo, C., Johnson, C., Bradman, A., Barr, D.B. and Eskenazi, B. 2011. Prenatal exposure to organophosphate pesticides and IQ in 7-year-old children. Environmental Health Perspectives, 119: 1189-1195.
    Search in Google Scholar
  5. Chen, S.C. and Liao, C.M. 2006. Health risk assessment on human exposed to environmental polycyclic aromatic hydrocarbons pollution sources. Science of the Total Environment, 366: 112-123.
    Search in Google Scholar
  6. David, D., George, I.A. and Peter, J.V. 2007. Toxicology of the newer neonicotinoid insecticides: imidacloprid poisoning in a human. Clinical Toxicology, 45: 485-486.
    Search in Google Scholar
  7. Dawson, A.H., Eddleston, M., Senarathna, L., Mohamed, F., Gawarammana, I., Bowe, S.J., Manuweera, G. and Buckley, N.A. 2010. Acute human lethal toxicity of agricultural pesticides: a prospective cohort study. PLoS Medicine, 7: e1000357.
    Open DOISearch in Google Scholar
  8. Decourtye, A., Armengaud, C., Renou, M., Devillers, J., Cluzeau, S., Gauthier, M. and Pham-Delegue, M-H. 2003. Imidacloprid impairs memory and brain metabolism in the honeybee (Apis mellifera L.). Pesticide Biochemistry and Physiology, 78: 83-92.
    Search in Google Scholar
  9. de Pinho, G.P., Neves, A.A., de Queiroz, M.E.L.R. and Silverio, F.O. 2010. Optimization of the liquid- liquid extraction method and low temperature purifi cation (LLE-LTP) for pesticide residue analysis in honey samples by gas chromatography. Food Control, 21: 1307-1311.
    Search in Google Scholar
  10. Dockery, D.W. and Pope, C.A. 3rd. 1994. Acute respiratory eff ects of particulate air pollution. Annual Review of Public Health, 15: 107-132.
    Search in Google Scholar
  11. Domingo, J.L., Marti-Cid, R., Castell, V. and Llobet, J.M.. 2008. Human exposure to PBDEs through the diet in Catalonia, Spain: temporal trend. A review of recent literature on dietary PBDE intake. Toxicology, 248: 25-32.
    Search in Google Scholar
  12. ECOPEST, http://www.ecopest.gr/index.php?lang=en.accessed at 25-05-2015.
    Search in Google Scholar
  13. Engel, S.M., Berkowitz, G.S., Barr, D.B., Teitelbaum, S.L., Siskind, J., Meisel, S.J., Wetmur, J.G. and Wolff , M.S., 2007. Prenatal organophosphate metabolite and organochlorine levels and performance on the Brazelton Neonatal Behavioral Assessment Scale in a multiethnic pregnancy cohort. American Journal of Epidemiology, 165: 1397-1404.
    Open DOISearch in Google Scholar
  14. Forrester, M. 2014. Neonicotinoid insecticide exposures reported to six poison centers in Texas. Human & Experimental Toxicology, 33: 568-573.
    Search in Google Scholar
  15. Fuke, C., Nagai, T., Ninomiya, K., Fukasawa, M., Ihama, Y. and Miyazaki, T. 2014. Detection of imidacloprid in biological fl uids in a case of fatal insecticide intoxication. Legal Medicine, 16: 40-43.
    Search in Google Scholar
  16. Gagliardi, B. and Pettigrove, V. 2013. Removal of Intensive Agriculture from the Landscape Improves Aquatic Ecosystem Health. Agriculture, Ecosystems and Environment, 176: 1-8.
    Search in Google Scholar
  17. Goulson, D., Nicholls, E., Botias, C. and Rotheray, E.L. 2015. Bee declines driven by combined stress from parasites, pesticides, and lack of fl owers. Science 347: no. 6229
    Open DOISearch in Google Scholar
  18. Gunnell, D. and Eddleston, M. 2003. Suicide by intentional ingestion of pesticides: a continuing tragedy in developing countries. International Journal of Epidemiology, 32: 902-909.
    Search in Google Scholar
  19. Hatjina, F., Papaefthimiou, C., Charistos, L., Dogaroglu, T., Bouga, M., Emmanouil, C. and Arnold, G. 2013. Sublethal doses of imidacloprid decreased size of hypopharyngeal glands and respiratory rhythm of honeybees in vivo. Apidologie, 44: 467-480.
    Search in Google Scholar
  20. Hernandez, F., Sancho, J.V. and Pozo, O.J., 2005. Critical review of the application of liquid chromatography/ mass spectrometry to the determination of pesticide residues in biological samples. Analytical and Bioanalytical Chemistry, 382: 934-946.
    Open DOISearch in Google Scholar
  21. ICH, 2005. Validation of Analytical Procedures: Text and Methodology Q2(R1) http://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Quality/Q2_R1/Step4/Q2_R1__Guideline.pdf.
    Search in Google Scholar
  22. Inoue, S., Saito, T., Mase, H., Suzuki, Y., Takazawa, K., Yamamoto, I. and Inokuchi, S. 2007. Rapid simultaneous determination for organophosphorus pesticides in human serum by LC-MS. Journal of Pharmaceutical and Biomedical Analysis, 44: 258-264.
    Search in Google Scholar
  23. Iyyadurai, R., George, I.A. and Peter, J.V. 2010. Imidacloprid poisoning--newer insecticide and fatal toxicity. Journal of Medical Toxicology, 6: 77-78.
    Search in Google Scholar
  24. Jamin, E.L., Bonvallot, N., Tremblay-Franco, M., Cravedi, J.P., Chevrier, C., Cordier, S. and Debrauwer, L. 2014. Untargeted profi ling of pesticide metabolites by LC-HRMS: an exposomics tool for human exposure evaluation. Analytical and Bioanalytical Chemistry, 406: 1149-1161.
    Search in Google Scholar
  25. Jia, G., Lv, C., Zhu, W., Qiu, J., Wang, X. and Zhou, Z. 2008. Applicability of cloud point extraction coupled with microwave-assisted back-extraction to the determination of organophosphorous pesticides in human urine by gas chromatography with fl ame photometry detection. Journal of Hazardous Materials, 159: 300-305.
    Search in Google Scholar
  26. Jones, A.K. and Sattelle, D.B. 2010. Diversity of Insect Nicotinic Acetylcholine Receptor Subunits. Pp. 25-43. In: Insect Nicotinic Acetylcholine Receptors, Advances in Experimental Medicine and Biology series, Vol 683 (Thany, S.H., ed.) Springer Science & Business Media, LLC, Landes Bioscience, New York, USA.
    Open DOISearch in Google Scholar
  27. Kasiotis, K.M., Kyriakopoulou, K., Emmanouil, C., Tsantila, N., Liesivuori, J., Souki, H., Manakis, S. and Machera, K. 2012. Monitoring of systemic exposure to plant protection products and DNA damage in orchard workers. Toxicology Letters, 210: 182-188.
    Search in Google Scholar
  28. Kasiotis, K.M., Souki, H., Carageorgiou, H. and Machera, K. 2011. Determination of dimethoate and omethoate in human serum samples. Risk assessment for the operator. International Journal of Environmental Analytical Chemistry, 91: 876-883.
    Search in Google Scholar
  29. Kasiotis, K.M., Souki, H., Tsakirakis, A.N., Carageorgiou, H., Theotokatos, S.A., Haroutounian, S.A., Machera, K. 2008. Headspace solid phase micro extraction gas chromatographic determination of fenthion in human serum. International Journal of Molecular Sciences, 9: 906-913.
    Search in Google Scholar
  30. Kataoka, H. 2003. New trends in sample preparation for clinical and pharmaceutical analysis. Trends in Analytical Chemistry, 22: 232-244.
    Search in Google Scholar
  31. Kole, P.L., Venkatesh, G., Kotecha, J. and Sheshala, R. 2011. Recent advances in sample preparation techniques for eff ective bioanalytical methods. Biomedical Chromatography: BMC, 25: 199-217.
    Search in Google Scholar
  32. Kong, Y. and Zhang, J. 2010. Access to farming pesticides and risk for suicide in Chinese rural young people. Psychiatry Research, 179: 217-221.
    Search in Google Scholar
  33. Kumar, A., Verma, A. and Kumar, A. 2013. Accidental human poisoning with a neonicotinoid insecticide, imidacloprid: A rare case report from rural India with a brief review of literature. Egyptian Journal of Forensic Sciences, 3: 123-126.
    Search in Google Scholar
  34. La Farre, M., Perez, S., Kantiani, L. and Barcelo, D. 2008. Fate and toxicity of emerging pollutants, their metabolites and transformation products in the aquatic environment. Trends in Analytical Chemistry, 27: 991-1007.
    Search in Google Scholar
  35. Li, M. 2013. Automation in the bioanalytical laboratory: what is the future? Bioanalysis, 5: 2859-2861.
    Search in Google Scholar
  36. Li, M., Chou, J., King, K.W. and Yang, L. 2013. ASPECTS: an automation-assisted SPE method development system. Bioanalysis, 5: 1661-1676.
    Open DOISearch in Google Scholar
  37. Lin, P.C., Lin, H.J., Liao, Y.Y., Guo, H.R. and Chen, K.T. 2013. Acute poisoning with neonicotinoid insecticides: a case report and literature review. Basic & Clinical Pharmacology & Toxicology, 112: 282-286.
    Search in Google Scholar
  38. Lu, C., Barr, D.B., Pearson, M.A. and Waller, L.A. 2008. Dietary intake and its contribution to longitudinal organophosphorus pesticide exposure in urban/suburban children. Environmental Health Perspectives, 116: 537-542.
    Search in Google Scholar
  39. Lu, C., Warchol, K.M. and Callahan, R.A. 2014. Sub-lethal exposure to neonicotinoids impaired honey bees winterization before proceeding to colony collapse disorder. Bulletin of Insectology, 67: 125-130.
    Search in Google Scholar
  40. Marti-Cid, R., Llobet, J.M., Castell, V. and Domingo, J.L. 2008a. Evolution of the dietary exposure to polycyclic aromatic hydrocarbons in Catalonia, Spain. Food and Chemical Toxicology, 46: 3163-3171.
    Search in Google Scholar
  41. Marti-Cid, R., Llobet, J.M., Castell, V. and Domin go, J.L. 2008b. Human dietary exposure to hexachlorobenzene in Catalonia, Spain. Journal of Food Protection, 71: 2148-2152.
    Search in Google Scholar
  42. Marti-Cid, R., Llobet, J.M., Castell, V. and Domingo, J.L. 2008c. Human exposure to polychlorinated naphthalenes and polychlorinated diphenyl ethers from foods in Catalonia, Spain: temporal trend. Environmental Science & Technology, 42: 4195-4201.
    Search in Google Scholar
  43. Matsuda, K., Shimomura, M., Ihara, M., Akamatsu, M. and Sattelle, D.B. 2005. Neonicotinoids show selective and diverse actions on their nicotinic receptor targets: electrophysiology, molecular biology, and receptor modeling studies. Bioscience, Biotechnology, and Biochemistry, 69: 1442-1452.
    Search in Google Scholar
  44. Mohamed, F., Gawarammana, I., Robertson, T.A., Roberts, M.S., Palangasinghe, C., Zawahir, S., Jayamanne, S., Kandasamy, J., Eddleston, M., Buckley, N.A., Dawson, A.H. and Roberts, D.M. 2009. Acute human self-poisoning with imidacloprid compound: a neonicotinoid insecticide. PloS one, 4: e5127.
    Open DOISearch in Google Scholar
  45. Nauen, R., Ebbinghaus-Kintscher, U. and Schmuck, R. 2001. Toxicity and nicotinic acetylcholine receptor interaction of imidacloprid and its metabolites in Apis mellifera (Hymenoptera: Apidae). Pest Management Science, 57: 577-586.
    Search in Google Scholar
  46. Nomura, H., Ueyama, J., Kondo, T., Saito, I., Murata, K., Iwata, T., Wakusawa, S. and Kamijima, M. 2013. Quantitation of neonicotinoid metabolites in human urine using GC-MS. Journal of Chromatography, B 941: 109-115.
    Search in Google Scholar
  47. Parron, T., Hernandez, A.F. and Villanueva, E. 1996. Increased risk of suicide with exposure to pesticides in an intensive agricultural area. A 12- year retrospective study. Forensic Science International, 79: 53-63.
    Search in Google Scholar
  48. Pollack, P. 2011. Fine chemicals: the industry and the business, 2nd edition ed. John Wiley & Sons, New Jersey.
    Search in Google Scholar
  49. Proenca, P., Teixeira, H., Castanheira, F., Pinheiro, J., Monsanto, P.V., Marques, E.P. and Vieira, D.N. 2005. Two fatal intoxication cases with imidacloprid: LC/MS analysis. Forensic Science International, 153: 75-80.
    Search in Google Scholar
  50. Ramanathan, R., Jemal, M., Ramagiri, S., Xia, Y.Q., Humpreys, W.G., Olah, T., Korfmacher, W.A., 2011. It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS. Journal of Mass Spectrometry, 46: 595-601.
    Open DOISearch in Google Scholar
  51. Simon-Delso, N., Amaral-Rogers, V., Belzunces, L.P., Bonmatin, J.M., Chagnon, M., Downs, C., Furlan, L., Gibbons, D.W., Giorio, C., Girolami, V., Goulson, D., Kreutzweiser, D.P., Krupke, C.H., Liess, M., Long, E., McField, M., Mineau, P., Mitchell, E.A., Morrissey, C.A., Noome, D.A., Pisa, L., Settele, J., Stark, J.D., Tapparo, A., Van Dyck, H., Van Praagh, J., Van der Sluijs, J.P., Whitehorn, P.R. and Wiemers, M. 2015. Systemic insecticides (neonicotinoids and fi pronil): trends, uses, mode of action and metabolites. Environmental Science and Pollution Research, 22: 5-34.
    Search in Google Scholar
  52. Taira, K. 2014. Human neonicotinoids exposure in Japan. Japanese Journal of Clinical Ecology, 23: 14-24.
    Search in Google Scholar
  53. Taira, K., Aoyama, Y., Kawakami, T., Kamata, M. and Aoi, T. 2011. Detection of chrolopyridinyl neonicotinoid insecticide metbolite 6-chloronicotinic aicd in the urine: Six cases with subacute nicotinic symptoms. Japan Journal of Clinical Toxicology, 24: 222-230.
    Search in Google Scholar
  54. Taira, K., Fujioka, K. and Aoyama, Y. 2013. Qualitative profi ling and quantifi cation of neonicotinoid metabolites in human urine by liquid chromatography coupled with mass spectrometry. PloS one, 8: e80332.
    Search in Google Scholar
  55. Togola, A., Baran, N. and Coureau, C. 2014. Advantages of online SPE coupled with UPLC/MS/MS for determining the fate of pesticides and pharmaceutical compounds. Analytical and Bioanalytical Chemistry, 406: 1181-1191.
    Search in Google Scholar
  56. Tomizawa, M., Maltby, D., Medzihradszky, K.F., Zhang, N., Durkin, K.A., Presley, J., Talley, T.T., Taylor, P., Burlingame, A.L. and Casida, J.E. 2007a. Defi ning nicotinic agonist binding surfaces through photoaffi nity labeling. Biochemistry, 46: 8798-8806.
    Search in Google Scholar
  57. Tomizawa, M., Talley, T.T., Maltby, D., Durkin, K.A., Medzihradszky, K.F., Burlingame, A.L., Taylor, P. and Casida, J.E. 2007b. Mapping the elusive neonicotinoid binding site. Proceedings of the National Academy of Sciences of the United States of America, 104: 9075-9080.
    Search in Google Scholar
  58. Ueyama, J., Nomura, H., Kondo, T., Saito, I., Ito, Y., Osaka, A. and Kamijima, M. 2014. Biological monitoring method for urinary neonicotinoid insecticides using LC-MS/MS and its application to Japanese adults. Journal of Occupational Health, 56: 461-468.
    Search in Google Scholar
  59. Uroz, F.J., Arrebola, F.J., Egea-Gonzalez, F.J. and Martinez- Vidal, J.L. 2001. Monitoring of 6-chloronicotinic acid in human urine by gas chromatography- tandem mass spectrometry as indicator of exposure to the pesticide imidacloprid. Analyst, 126: 1355-1358.
    Open DOISearch in Google Scholar
  60. Van Eeckhaut, A., Lanckmans, K., Sarre, S., Smolders, I. and Michotte, Y. 2009. Validation of bioanalytical LC-MS/MS assays: evaluation of matrix eff ects. Journal of Chromatography B, 877: 2198-2207.
    Search in Google Scholar
  61. Vanengelsdorp, D., Evans, J.D., Saegerman, C., Mullin, C., Haubruge, E., Nguyen, B.K., Frazier, M., Frazier, J., Cox-Foster, D., Chen, Y., Underwood, R., Tarpy, D.R. and Pettis, J.S. 2009. Colony collapse disorder: a descriptive study. PloS one, 4: e6481.
    Search in Google Scholar
  62. Wu, I.W., Lin, J.L., Cheng, E.T., 2001. Acute poisoning with the neonicotinoid insecticide imidacloprid in N-methyl pyrrolidone. Clinical Toxicology, 39: 617-621.
    Open DOISearch in Google Scholar
  63. Xiao, J.F., Zhou, B. and Ressom, H.W. 2012. Metabolite identifi cation and quantitation in LC-MS/ MS-based metabolomics. Trends in Analytical Chemistry, 32: 1-14.
    Search in Google Scholar
  64. Yamamuro, T., Ohta, H., Aoyama, M. and Watanabe, D., 2014. Simultaneous determination of neonicotinoid insecticides in humanserum and urine using diatomaceous earth-assisted extraction andliquid chromatography-tandem mass spectrometry. Journal of Chromatography, B 969: 85-94.
    Open DOISearch in Google Scholar
  65. Yeh, I.J., Lin, T.J., Hwang, D.Y., 2010. Acute multiple organ failure with imidacloprid and alcohol ingestion. The American Journal of Emergency Medicine, 28, 255 e251-253.
    Open DOISearch in Google Scholar
  66. Yeter, O., Aydin, A., 2014. Determination of acetamiprid and IM-1-2 in postmortem human blood, liver, stomach contents by HPLC-DAD. Journal of Forensic Sciences, 59: 287-292.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.1515/hppj-2015-0006 | Journal eISSN: 2732-656X (formerly 1791-3691) | Journal ISSN: 1791-3691
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Language: English
Page range: 33 - 45
Submitted on: Jun 1, 2015
Accepted on: Jun 25, 2015
Published on: Jul 14, 2015
Published by: Benaki Phytopathological Institute
In partnership with: Paradigm Publishing Services
Keywords:
LC-MS,
urine,
Imidacloprid
Related subjects:
Life sciences,
Plant science,
Zoology,
Life sciences, other

© 2015 K.M. Kasiotis, K. Machera, published by Benaki Phytopathological Institute
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 8 (2015): Issue 2 (July 2015)
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