Have a personal or library account? Click to login
Cardiotoxicity of the adjuvant trastuzumab in a Saudi population: clinical experience of a single institution Cover

Cardiotoxicity of the adjuvant trastuzumab in a Saudi population: clinical experience of a single institution

Open Access
|Dec 2016

References

  1. Hortobagyi GN, de la Garza SJ, Pritchard K, et al: The global breast cancer burden: variations in epidemiology and survival. Clin Breast Cancer 2005, 6:391-401.
  2. Albain KS, de la Garza SJ, Pienkowski T, et al: Reducing the global breast cancer burden: the importance of patterns of care research. Clin Breast Cancer 2005, 6:412-420.
  3. Slamon DJ, Clark GM, Wong SG, et al: Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235:177-182, 1987
  4. Slamon DJ, Godolphin W, Jones LA, et al: Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244:707-712,1999
  5. Force T, Krause DS, Van Etten RA: Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition. Nat Rev Cancer 2007, 7:332-344.
  6. Perez EA, Romond EH, Suman VJ, et al: Updated results of the combined analysis of NCCTG N9831 and NSABP B-31 adjuvant chemotherapy with/ without trastuzumab in patients with HER2- positive breast cancer. J Clin Oncol 25:6s, 2007 (suppl 18S; abstr 512)
  7. Romond EH, Perez EA, Bryant J, et al: Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 353: 1673-1684, 2005
  8. Slamon DJ, Eiermann W, Robert NJ, et al: Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel(ACT) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC-TH) with docetaxel, carboplatin and trastuzumab (TCH) in HER2neu positive early breast cancer patients: BCIRG006 study. Cancer Res 69:500s, 2009 (abstr 62)
  9. Piccart-Gebhart MJ, Procter M, Leyland- Jones B, et al: Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 353:1659-1672, 2005
  10. Smith I, Procter M, Gelber RD, et al: 2-Year followup of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: A randomized controlled trial. Lancet 369:29-36, 2007
  11. Hudis CA: Trastuzumab—mechanism of action and use in clinical practice. N Engl J Med 2007, 357:39-51.
  12. Yavas O, Yazici M, Eren O, Oyan B: The acute effect of trastuzumab infusion on ECG parameters in metastatic breast cancer patients. Swiss Med Wkly 2007, 137:556-558.
  13. Tsang W, Moe G. Trastuzumab and heart failure. Cardiol Rounds. 2007;8:1-6.
  14. Viani GA, Afonso SL, Stefano EJ, De Fendi LI, Soares FV: Adjuvant trastuzumab in the treatment of her-2-positive early breast cancer: a metaanalysis of published randomized trials. BMC Cancer 2007, 7:153.
  15. Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001; 344:783.
  16. Seidman A, Hudis C, Pierri MK, et al. Cardiac dysfunction in the trastuzumab clinical trials experience. J Clin Oncol 2002; 20:1215.
  17. Wysocki PJ, Hutka M: Cardiotoxicity of 5-fluorouracil in a young colorectal cancer patient - case report and review of literature. Arch Med Sci 2009, 5:277-280.
  18. McKeage K, Perry CM: Trastuzumab: a review of its use in the treatment of metastatic breast cancer overexpressing HER2. Drugs 2002, 62:209-243.
  19. Suter TM, Procter M, Van Veldhuisen DJ, Muscholl M, Bergh J, Carlomagno C, et al: Trastuzumab-associated cardiac adverse effects in the Herceptin Adjuvant Trial. J Clin Oncol 2007, 25:3859-3865.
  20. Telli M, et al: Trastuzumab-related cardiotoxicity: calling into question the concept of reversibility. JCO 2007, 25(23):3525-3533.
  21. Meryem Aitelhaj, Siham LKhouyaali, Ghizlane Rais, Amina Mohtaram, et al: Cardiac safety of the adjuvant Trastuzumab in a Moroccan population: observational monocentric study of about 100 patients. BMC Research Notes 2013, 6:339
  22. Slamon D, Eiermann W, Robert N: 006 oboB BCIRG 006:2nd interim analysis chase III randomised trial comparing doxorubicine and cyclophosphamide followed by docetaxel (AC/T) with doxorubicine and cyclo phosphamid followed by docetaxel and trastuzumab (AC/ETH) with docetaxel, carboplatin and trastuzumab (TCH) in Her2neu positive early breast cancer patients. In Proceedings of San Antonio breast cancer symposium (SABCS). San Antonio: Breast Cancer Research and Treatment; 2006.
  23. McArthur HL, Chia S: Cardiotoxicity of trastuzumab in clinical practice. N Engl J Med 2007, 357:94-95.
  24. Montemurro F, Redana S, Valabrega G, Martinello R, Aglietta M, Almiero R: Trastuzumab-related cardiotoxicity in the herceptin dyuvant trial.J Clin Oncol 2008, 26:2052-2053.
  25. Tan-Chiu E, Yothers G, Romond E, et al: Assessment of cardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in nodepositive, human epidermal growth factor receptor 2-over - expressing breast cancer: NSABP B-31. J Clin Oncol 2005, 23:7811-7819.
  26. Ewer MS, Vooletich MT, Durand JB, et al: Reversibility of trastuzumab related cardiotoxicity: new insights based on clinical course and response to medical treatment. J Clin Oncol 2005, 23:7820-7826.
  27. Wadhwa D, Fallah-Rad N, Grenier D, et al: Trastuzumab mediated cardiotoxicity in the setting of adjuvant chemotherapy for breast cancer: a retrospective study. Breast Cancer Res Treat 2009, 117:357-364.
  28. Sengupta PP, Northfelt DW, Gentile F, Zamorano JL, Khandheria BK: Trastuzumab-induced cardiotoxicity: heart failure at the crossroads. Mayo Clin Proc 2008, 83:197-203.
  29. Gluba A, Pietrucha T, Banach M, Piotrowski G, Rysz J: The role of polymorphisms within paraoxonases (192 Gln/Arg in PON1 and 311Ser/Cys in PON2) in the modulation of cardiovascular risk: a pilot study. Angiology 2010, 61:157-165.
  30. Perez EA, Suman VJ, Davidson NE, et al: Cardiac safety analysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the NorthCentral Cancer Treatment Group N9831 adjuvant breast cancer trial. J Clin Oncol 2008, 26:1231-1238.
  31. Pentassuglia L, Graf M, Lane H, et al: Inhibition of ErbB2 by receptor tyrosine kinase inhibitors causes myofibrillar structural damage without cell death in adult rat cardiomyocytes. Exp Cell Res 2009, 315:1302-1312.
  32. Bowles A: Risk of heart failure in breast cancer patients after anthracyclines and Trastuzumab treatment: a retrospective cohort study. J Natl Cancer Inst 2012, 104:1293-1305.
  33. Tocchetti C., Ragone G., Coppola C, et al: Detection, monitoring, and management of trastuzumab-induced left ventricular dysfunction: an actual challenge. Eur J Heart Fail 2012,14: 130-137.
  34. Braden A., Stankowski R., Engel J., et al: Breast cancer biomarkers: risk assessment, diagnosis, prognosis, prediction of treatment efficacy and toxicity, and recurrence. Curr Pharm Des 25 November 2013 (Epub ahead of print).
DOI: https://doi.org/10.1515/fco-2016-0007 | Journal eISSN: 1792-362X | Journal ISSN: 1792-345X
Language: English
Page range: 1 - 6
Submitted on: Feb 23, 2016
Accepted on: Oct 14, 2016
Published on: Dec 30, 2016
Published by: Helenic Society of Medical Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year

© 2016 Rasha Hamdy Hamed, Khalid Salim, Abdullah Alzahrani, Shereef Elsamany, published by Helenic Society of Medical Oncology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.