An alternative synthesis of Azilsartan: an angiotensin II receptor blocker

Srinivas Garaga; Nimesh C. Misra; Ambati V. Raghava Reddy; Koilpillai Joseph Prabahar; Chandiran Takshinamoorthy; Paul Douglas Sanasi; Raghubabu Korupolu

doi:10.1515/cipms-2015-0047

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An alternative synthesis of Azilsartan: an angiotensin II receptor blocker

Current Issues in Pharmacy and Medical Sciences

Volume 28 (2015): Issue 2 (June 2015)

By: Srinivas Garaga, Nimesh C. Misra, Ambati V. Raghava Reddy, Koilpillai Joseph Prabahar, Chandiran Takshinamoorthy, Paul Douglas Sanasi and Raghubabu Korupolu

Open Access

|Jul 2015

Abstract

This paper provides a description of an alternative, novel and commercially viable process which has been developed for the preparation of Azilsartan, a pro-drug of Azilsartan medoxomil, an angiotensin II receptor blocker. The present work also provides a primary account of the synthesis and characterization of the novel intermediates (6, 7 & 10) of Azilsartan, with their spectral data.

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Articles in this issue

DOI: https://doi.org/10.1515/cipms-2015-0047 | Journal eISSN: 2300-6676 | Journal ISSN: 2084-980X

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Language: English

Page range: 72 - 76

Submitted on: Nov 14, 2014

Accepted on: Mar 27, 2015

Published online: Jul 16, 2015

Published in print: Jun 1, 2015

Published by: Sciendo

In partnership with: Paradigm Publishing Services

Keywords:

Azilsartan,

novel intermediates,

synthesis and characterization

Related subjects:

Medicine,

Clinical medicine,

Pharmacology, toxicology

© 2015 Srinivas Garaga, Nimesh C. Misra, Ambati V. Raghava Reddy, Koilpillai Joseph Prabahar, Chandiran Takshinamoorthy, Paul Douglas Sanasi, Raghubabu Korupolu, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 28 (2015): Issue 2 (June 2015)