Comparison of RNA-Seq Differential Expression Methods

Palejev, Dean

doi:10.1515/cait-2017-0055

Abstract

There are many methods designed to find differentially expressed genes using RNA-seq data. Their outputs differ a lot, some genes are determined to be differentially expressed by most or all methods, and others - by very few or even by just one method. Here we derive a systematic approach to quantifying the proximity of such methods, allowing us also to discover patterns and to determine whether some of them are significantly different than others.

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Comparison of RNA-Seq Differential Expression Methods

Abstract

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