Figure 1
Identification of the mtDNA 4977 bp deletion. M: DL2000 Marker; lane 1: control subjects without the 4977 bp deletion; lanes 2 and 3: patients with the mtDNA 4977 bp deletion.
Table 1
Characterization of patients with hepatocellular carcinoma.
| Parameters | Number of HCC Patients | mtDNA 4977 bp Deletion Frequency n (%) |
|---|---|---|
| Cases | 104 | 10 (9.52) |
| Males | 65 | 6 (5.71) |
| Females | 40 | 4 (3.81) |
| Age ≥ 55 | 75 | 7 (6.67) |
| Age <55 | 30 | 3 (2.85) |
| History of alcohol consumption: | ||
| yes | 85 | 10 (9.52) |
| no | 20 | 0 (0.00) |
| Metastasis: | ||
| positive | 35 | 4 (3.81) |
| negative | 70 | 6 (5.71) |
[i] HCC: hepatocellular carcinoma; mtDNA: mitochondrial DNA; n: number.
Figure 2
Comparison of mtDNA content between HCC patients with the mtDNA 4977 bp deletion and control subjects.
Figure 3
Reactive oxygen species concentrations in HCC patients carrying the mtDNA 4977 bp deletion and control subjects.