Table 1
The Student’s t-test results between the metabolic syndrome and control groups.
| Parameters | Arithmetic Mean | |||
|---|---|---|---|---|
| Control Group | MetS Group | t-Test | p Value | |
| Age (years) | 38.70 | 42.10 | −1.29 | 0.20 |
| BM (kg)a | 87.33 | 123.30 | −4.98 | 0.00 |
| BH (cm) | 170.13 | 170.86 | −0.16 | 0.87 |
| BMI (kg/m2)a | 25.99 | 41.50 | −8.97 | 0.00 |
| WC (cm)a | 88.90 | 125.67 | −9.77 | 0.00 |
| Systolic BP (mmHg)a | 120.50 | 139.37 | −4.91 | 0.00 |
| Diastolic BP (mmHg)a | 77.33 | 89.60 | −4.20 | 0.00 |
| TC (mmol/L) | 5.18 | 5.48 | 1.01 | 0.31 |
| Triglycerides (mmol/L)b | 3.57 | 2.12 | 2.33 | 0.02 |
| HDL cholesterol (mmol/L)a | 1.45 | 0.97 | 5.47 | 0.00 |
| LDL cholesterol (mmol/L)a | 2.29 | 3.68 | −5.19 | 0.00 |
| Non-HDL cholesterol (mmol/L) | 4.03 | 4.51 | −1.87 | 0.06 |
| LDL/HDL cholesterol (mmol/L)b | 3.27 | 3.86 | −2.79 | 0.01 |
| Glycemia (mmol/L) | 4.67 | 5.18 | −1.93 | 0.06 |
| IRI (μU/mL) | 8.44 | 15.32 | −3.97 | 0.00 |
| HOMA IR (μU/mL)a | 1.80 | 3.65 | −3.76 | 0.00 |
| C-reactive protein (mg/L) | 1.88 | 12.62 | −4.58 | 0.00 |
BM: body mass; BH: body height; BMI: body mass index; WC: waist circumference; Systolic BP: systolic blood pressure; Diastolic BP: diastolic BP;
TC: total cholesterol; TG: triglycerides; HDL cholesterol: high-density lipoprotein cholesterol; LDL cholesterol: low-density cholesterol;
IRI: insulin level HOMA IR: homeostasis model assessment of insulin resistance; CRP: C-reactive protein.
Table 2
Frequencies of the LRP1 exon 3 alleles.
| Group | Allele | Total | |
|---|---|---|---|
| C (%) | T (%) | ||
| MetS group | 74.60 | 25.40 | 100.00 |
| Control group | 93.33 | 6.67 | 100.00 |
| Total | 80.65 | 19.35 | 100.00 |
Table 3
One-way analysis of variance between the exon 3 LRP1 gene and tested relevant anthropometric and biochemical parameters.
| ANOVA | Exon 3 LRP1 Gene | |
|---|---|---|
| Parameter | F = VA/VR | p Value |
| BMI (kg/m2) | 4.47 | 0.010 |
| WC (cm) | 6.59 | 0.000 |
| Systolic BP (mmHg) | 4.67 | 0.012 |
| LDL cholesterol (mmol/L) | 40.54 | 0.000 |
| Index of atherosclerosis LDL/HDL | 11.52 | 0.000 |
[i] ANOVA: analysis of variance; F = VA/VR: statistics of F test is the ratio of factorial and residual variance; BMI: body mass index;
WC: waist circumference; Systolic BP: systolic blood pressure; LDL: low-density lipoprotein/high-density lipoprotein cholesterol.
Table 4
Odds ratio for the exon 3 LRP1 gene allele and measured anthropometric and biochemical parameters.
| Parameters | Allele | C | T |
|---|---|---|---|
| BMI (<30 kg/m2) | OR | 0.23 | 4.24 |
| 95% CI | 0.07-0.70 | 1.42-12.65 | |
| p value | >0.05 | <0.05 | |
| LDL cholesteror (>3 mmol/L) | OR | 0.04 | 20.26 |
| 95% CI | 0.00-0.37 | 2.70-152.04 | |
| p value | >0.05 | <0.05 |
[i] BMI: body mass index; OR: odds ratio; 95% CI: 95% confidence interval; LDL cholesterol: low-density lipoprotein cholesterol.