Variants in mitochondrial tRNA gene may not be associated with thyroid carcinoma

tRNA	tRNA^Asp	tRNA^Arg		tRNA^Leu(CUN)	tRNA^Ile		tRNA^Ala
Nt changes	G7521A	T10411C	T10463C	A12308G	G4292C	C4312T	T5655C
Number of nts in tRNA	4	7	67	44	34	54	1
Position	acceptor arm	acceptor arm	acceptor arm	variable loop	anticodon arm	T arm	acceptor arm
Homoplasmy/heteroplasmy	homoplasmy	homoplasmy	homoplasmy	homoplasmy	homoplasmy	homoplasmy	homoplasmy
CI (%)	13.5	21.1	94.2	93.3	10.0	19.0	71.2
G (wild type)(kcal/mol)	‒10.59	‒10.58	‒10.86	‒16.01	‒8.98	‒8.98	‒18.47
G (mutant)(kcal/mol)	‒11.11	‒10.13	‒10.13	‒15.88	‒9.06	‒9.12	‒18.81

CI: conservation index.

DOI: https://doi.org/10.1515/bjmg-2015-0090 | Journal eISSN: 2199-5761 (formerly 1311-0160) | Journal ISSN: 1311-0160

Language: English

Page range: 59 - 64

Published on: Jul 9, 2016

Published by: Macedonian Academy of Sciences and Arts

In partnership with: Paradigm Publishing Services

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© 2016 F Lv, G Qian, W You, H Lin, XF Wang, GS Qiu, YS Jiang, LX Pang, YM Kang, BF Jia, JZ Xu, Y Yu, published by Macedonian Academy of Sciences and Arts
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.