The Role of Eosinophilic Cationic Proteins, Total IgE and Eosinophilia in Children with Bronchial Hyperresponsiveness

Bronchial hyperreactivity (HRB), is defined as an excessive bronchial constriction that acts as an exaggerated bronchoconstrictor of the airways. This occurs as a secondary action of a nonspecific stimuli.

Taking as a starting point asthmatic patient, as the patient responds by bronchoconstriction action of various stimuli, the concept of bronchial hyperractivity gradually began to take shape. Bronchial hyperractivity (HRB) can be considered a major, heterogeneous phenomenon, depending on several conditions, in term of etiology and which gathers the features of a genuine syndrome if we consider the complexity of the mechanisms which produce and countless clinical implications.