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Relapsing Polychondritis Possibly Caused by Chronic Infection with Borrelia Burgdorferi – Case Report Cover

Relapsing Polychondritis Possibly Caused by Chronic Infection with Borrelia Burgdorferi – Case Report

Open Access
|Jun 2015

Abstract

Introduction: Relapsing polychondritis has been described by Rudolph von Jaksch Warthenhorst in 1923 under the name of polichondropathy. Although the etiology is unknown, an autoimmune mechanism is likely due to formation of autoantibodies to type II collagen in the extracellular matrix of the cartilage with its consequent destruction.

Case report: We present a case with relapsing polychondritis according to McAdam and Damiani criteria and with positive Western blot reaction for Ac IgG anti Borrelia burgdorferi. Serological reaction became negative and the patient presented favorable evolution at 6 months follow-up after corticosteroid therapy and antibiotics.

Conclusion: Chronic infection with Borrelia burgdorferi may play a role in relapsing polychondritis determinism

DOI: https://doi.org/10.1515/amma-2015-0018 | Journal eISSN: 2668-7763 | Journal ISSN: 2668-7755
Language: English
Page range: 57 - 59
Submitted on: Oct 27, 2014
Accepted on: Dec 15, 2014
Published on: Jun 16, 2015
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2015 S.H. Morariu, M.A. Badea, O.S. Cotoi, M.D. Vartolomei, Iudita-Maria Badea, M. Suciu, F. Buicu, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.