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Increased expression and secretion of recombinant hIFNγ through amino acid starvation-induced selective pressure on the adjacent HIS4 gene in Pichia pastoris Cover

Increased expression and secretion of recombinant hIFNγ through amino acid starvation-induced selective pressure on the adjacent HIS4 gene in Pichia pastoris

European Pharmaceutical Journal
Volume 62 (2015): Issue 2 (December 2015)
By: Ali Razaghi,  Roger Huerlimann,  Leigh Owens and  Kirsten Heimann  
Open Access
|Dec 2015

References

  1. [1] Arnone J, McAlear M. Adjacent gene pairing plays a role in the coordinated expression of ribosome biogenesis genes MPP10 and YJR003C in Saccharomyces cerevisiae. Eukaryot Cell. 2011;10:43-53.10.1128/EC.00257-10
    Search in Google Scholar
  2. [2] Arnone JT, Robbins-Pianka A, Arace JR, Kass-Gergi S, McAlear MA. The adjacent positioning of co-regulated gene pairs is widely conserved across eukaryotes. BMC Genomics. 2012;13:546-561.10.1186/1471-2164-13-546
    Search in Google Scholar
  3. [3] Babu M, Luscombe N, Aravind L, Gerstein M, Teichmann S. Structure and evolution of transcriptional regulatory networks. Curr Opin Struct Biol. 2004;14:283-291.10.1016/j.sbi.2004.05.004
    Search in Google Scholar
  4. [4] Berger A, Cabal G, Fabre E et al. High-resolution statistical mapping reveals gene territories in live yeast. Nature Methods. 2008;5:1031-1037.10.1038/nmeth.1266
    Search in Google Scholar
  5. [5] Boutanaev AM, Kalmykova AI, Shevelyov YY, Nurminsky DI. Large clusters of co-expressed genes in the Drosophila genome. Nature. 2002;420:666-669.10.1038/nature01216
    Search in Google Scholar
  6. [6] Bozinovic G, Sit TL, Di Giulio R, Wills LF, Oleksiak MF. Genomic and physiological responses to strong selective pressure during late organogenesis: few gene expression changes found despite striking morphological differences. BMC Genomics. 2013;14:779-794.10.1186/1471-2164-14-779
    Search in Google Scholar
  7. [7] Dai M, Lu H. Crosstalk between c-Myc and ribosome in ribosomal biogenesis and cancer. J Cell Biochem. 2008;105:670-677.10.1002/jcb.21895
    Search in Google Scholar
  8. [8] Daxinger L, Whitelaw E. Transgenerational epigenetic inheritance: More questions than answers. Genome Res. 2010;20:1623-1628.10.1101/gr.106138.110
    Search in Google Scholar
  9. [9] Deng Y, Dai X, Xiang Q et al. Genome-wide analysis of the effect of histone modifications on the coexpression of neighboring genes in Saccharomyces cerevisiae. BMC Genomics. 2010;11:550-566.10.1186/1471-2164-11-550
    Search in Google Scholar
  10. [10] Duan Z, Andronescu M, Schutz K et al. A three-dimensional model of the yeast genome. Nature. 2010;465:363-367.10.1038/nature08973
    Search in Google Scholar
  11. [11] Ebisuya M, Yamamoto T, Nakajima M, Nishida E. Ripples from neighbouring transcription. Nature Cell Biol. 2008;10:1106-1113.10.1038/ncb1771
    Search in Google Scholar
  12. [12] Fraser HB. Gene expression drives local adaptation in humans. Genome Res. 2013;23:1089-1096.10.1101/gr.152710.112
    Search in Google Scholar
  13. [13] Gilad Y, Oshlack A, Rifkin SA. Natural selection on gene expression. Trends Genet. 2006;22:456-461.10.1016/j.tig.2006.06.002
    Search in Google Scholar
  14. [14] Grewal S, Li L, Orian A, Eisenman R, Edgar B. Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development. Nature Cell Biol. 2005;7:295-302.10.1038/ncb1223
    Search in Google Scholar
  15. [15] Grunstein M. Molecular model for telomeric heterochromatin in yeast. Curr Opin Cell Biol. 1997;9:383-387.10.1016/S0955-0674(97)80011-7
    Search in Google Scholar
  16. [16] Hinnebusch AG. Translational regulation of GCN4 and the general amino acid control of yeast. Annu Rev Microbiol. 2005;59:407-450.10.1146/annurev.micro.59.031805.133833
    Search in Google Scholar
  17. [17] Hinnebusch AG, Natarajan K. Gcn4p, a master regulator of gene expression, is controlled at multiple levels by diverse signals of starvation and stress. Eukaryotic Cell. 2002;1:22-32.10.1128/EC.01.1.22-32.2002
    Search in Google Scholar
  18. [18] Hurst LD, Pal C, Lercher MJ. The evolutionary dynamics of eukaryotic gene order. Nature Rev Genet. 2004;5:299-310.10.1038/nrg1319
    Search in Google Scholar
  19. [19] Kruglyak S, Tang H. Regulation of adjacent yeast genes. Trends Genet. 2000;16:109-111.10.1016/S0168-9525(99)01941-1
    Search in Google Scholar
  20. [20] Lamas-Maceiras M, Cerdan ME, Freire-Picos MA. Kluyveromyces lactis HIS4 transcriptional regulation: similarities and differences to Saccharomyces cerevisiae HIS4 gene. FEBS Lett. 1999;458:72-76.10.1016/S0014-5793(99)01105-9
    Search in Google Scholar
  21. [21] Lercher MJ, Blumenthal T, Hurst LD. Coexpression of neighboring genes in Caenorhabditis elegans is mostly due to operons and duplicate genes. Genome Res. 2003;13:238-243.10.1101/gr.553803
    Search in Google Scholar
  22. [22] Michalak P. Coexpression, coregulation, and cofunctionality of neighboring genes in eukaryotic genomes. Genomics. 2008;91:243-248.10.1016/j.ygeno.2007.11.002
    Search in Google Scholar
  23. [23] Miller CH, Maher SG, Young HA. Clinical use of interferon-gamma. Annals of the New York Academy of Sciences. 2009;1182:69-79.10.1111/j.1749-6632.2009.05069.x
    Search in Google Scholar
  24. [24] Natarajan K, Meyer MR, Jackson BM et al. Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast. Mol Cell Biol. 2001;21:4347-4368.10.1128/MCB.21.13.4347-4368.2001
    Search in Google Scholar
  25. [25] Osborne C, Chakalova L, Brown K et al. Active genes dynamically colocalize to shared sites of ongoing transcription. Nature Genet. 2004;36:1065-1071.10.1038/ng1423
    Search in Google Scholar
  26. [26] Purmann A, Toedling J, Schueler M et al. Genomic organization of transcriptomes in mammals: Coregulation and cofunctionality. Genomics. 2007;89:580-587.10.1016/j.ygeno.2007.01.010
    Search in Google Scholar
  27. [27] Sheehan KB, McInnerney K, Purevdorj-Gage B, Altenburg SD, Hyman LE. Yeast genomic expression patterns in response to low-shear modeled microgravity. BMC Genomics. 2007;8:3-15.10.1186/1471-2164-8-3
    Search in Google Scholar
  28. [28] Sproul D, Gilbert N, Bickmore WA. The role of chromatin structure in regulating the expression of clustered genes. Nature Rev Genet. 2005;6:775-781.10.1038/nrg1688
    Search in Google Scholar
  29. [29] Valenzuela L, Dhillon N, Dubey R, Gartenberg M, Kamakaka R. Long-range communication between the silencers of HMR. Mol Cell Biol. 2008;28:1924-1935.10.1128/MCB.01647-07
    Search in Google Scholar
  30. [30] Wade C, Umbarger M, McAlear M. The budding yeast rRNA and ribosome biosynthesis (RRB) regulon contains over 200 genes. Yeast. 2006;23:293-306.10.1002/yea.1353
    Search in Google Scholar
  31. [31] Wei W, Pelechano V, Jarvelin A, Steinmetz L. Functional consequences of bidirectional promoters. Trends Genet. 2011;27:267-276.10.1016/j.tig.2011.04.002
    Search in Google Scholar
  32. [32] Williams EJ, Bowles DJ. Coexpression of neighboring genes in the genome of Arabidopsis thaliana. Genome Res. 2004;14:1060-1067.10.1101/gr.2131104
    Search in Google Scholar
  33. [33] Zaman Z, Bowman SB, Kornfeld GD, Brown AJ, Dawes IW. Transcription factor GCN4 for control of amino acid biosynthesis also regulates the expression of the gene for lipoamide dehydrogenase. Biochem J. 1999;340:855-862.10.1042/bj3400855
    Search in Google Scholar
DOI: https://doi.org/10.1515/afpuc-2015-0031 | Journal eISSN: 2453-6725
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Language: English
Page range: 43 - 50
Submitted on: Aug 10, 2015
|
Accepted on: Oct 31, 2015
|
Published on: Dec 31, 2015
Published by: Comenius University in Bratislava, Faculty of Pharmacy
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year
Keywords:
Human interferon gamma,
Histidinol dehydrogenase,
Gcn4p,
Serial passage,
Transcriptional co-regulation
Related subjects:
Pharmacy,
Pharmacy, other

© 2015 Ali Razaghi, Roger Huerlimann, Leigh Owens, Kirsten Heimann, published by Comenius University in Bratislava, Faculty of Pharmacy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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