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Characterization of Intor:Swiss Albino Mice Adopted in the Institute of Virology, Vaccines and Sera – Torlak, Belgrade in the Early Twentieth Century Cover

Characterization of Intor:Swiss Albino Mice Adopted in the Institute of Virology, Vaccines and Sera – Torlak, Belgrade in the Early Twentieth Century

Open Access
|Sep 2016

Abstract

The Institute of Virology, Vaccines and Sera Torlak was established in 1927, while the first vaccine was produced in the Institute in 1930. Vaccines production implies using experimental animals, including mice, in in-process controls. The laboratory mice which have been in use in Torlak Institute from the very beginning belong to Swiss albino outbred stock. This stock, which has been in use for more than 80 years contains a large number of mice maintained at all times, was recently named Intor:Swiss. Biological characteristics of Intor:Swiss stock, are presented in this paper for the first time. Taking into account the presented characteristics, the Institute Torlak’s Swiss mice are suitable for use in pharmaceutical studies, vaccine development research and basic research, as well as in toxicological studies. The publication of data on the Intor:Swiss mice represents a contribution to the international scientific community, since it offers the possibility for obtaining an additional outbred mouse stock for research.

DOI: https://doi.org/10.1515/acve-2016-0025 | Journal eISSN: 1820-7448 | Journal ISSN: 0567-8315
Language: English
Page range: 279 - 293
Submitted on: Mar 16, 2016
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Accepted on: Aug 22, 2016
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Published on: Sep 29, 2016
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
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© 2016 Irena Živković, Irena Rajnpreht, Rajna Minić, Katarina Mitić, Iva Aleksić, Jasminka Kadrić, Vladimir Petrušić, published by University of Belgrade, Faculty of Veterinary Medicine
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.