Nasal Transmissible Venereal Tumor In A Jack Russel Terrier Bitch

FEGHIU Adrian; CRÎNGANU Dan; DUMITRESCU Florin; PASCAL Manuela; VASILESCU Florina; MILITARU Manuella

doi:10.1515/acve-2015-0012

Abstract

A two-year old Jack Russell Terrier female with left-sided epistaxis was brought to the Clinic of the Bucharest Faculty of Veterinary Medicine. Endoscopy of the left nasal cavity revealed a cauliflower-like mass. Cytological and histopathological features were specific to canine transmissible venereal tumour (CTVT). Tumor tissue showed positive immunoreactivity to anti-vimentin monoclonal antibody (90%) and Ki67 (35%) and samples were negative for anti-cytokeratin monoclonal antibody. Chemotherapy with vincristine sulphate at a dose of 0.025 mg/kg i.v./week for 6 administrations was successful. This paper presents a primary form of nasal CTVT in a Jack Russell Terrier female.

References

1. Baştan A, Baki DA, Cengiz M: Uterine and Ovarian Metastasis of Transmissible Venereal Tumor in a Bitch. Turk J Vet Anim Sci 2008, 32(1): 65-66.
Search in Google Scholar
2. Das U, Das AK: Review of canine transmissible venereal sarcoma. Veterinary Research Commun 2000, 24: 545-56.10.1023/A:1006491918910
Search in Google Scholar
3. Feghiu A, Militaru M: Tumora veneriană transmisibilă canină. Rev Rom Med Vet 2013, 23: 2: 29-41 (article in Romanian with an abstract in English).
Search in Google Scholar
4. Levy E, Mylonakis ME, Saridomichelakis MN, Polizopoulou ZS, Psychogios V, Koutinas AF: Nasal and oral masses in a dog. Vet Clin Pathol 2006, 35: 115–118.10.1111/j.1939-165X.2006.tb00100.x
Search in Google Scholar
5. Papazoglou LG, Koutinas AF, Plevraki AG, Tontis D: Primary Intranasal Transmissible Venereal Tumour in the Dog: A Retrospective Study of Six Spontaneous Cases. J Vet Med A 2001, 48: 391-400.10.1046/j.1439-0442.2001.00361.x
Search in Google Scholar
6. Silva MCV, Daleck CR, Ramos RS, De Nardi AB, Martins MR, Calazans SG, Eurides: Primary Intranasal Transmissible venereal tumor with bone lysis of the maxilla and metastasis: Case Report. Ars Veterinaria Jaboticabal, SP 2007, 23: 1: 054-058.
Search in Google Scholar
7. Mylonakis ME, Saridomichelakis MN, Lazaridis V, Leontidesy LS, Kostoulasy P, Koutinas AF. A retrospective study of 61 cases of spontaneous canine epistaxis (1998 to 2001). Journal of Small Animal Practice 2008; 49: 191–196.10.1111/j.1748-5827.2007.00441.x
Search in Google Scholar
8. Forrest TL. The Granial and Nasal Cavities-Canine and Feline. In: Thrall ED, editor. Texbook of Veterinary Diagnostic Radiology. 4th ed. Philadelphia, USA: Saunders, 2002: pp. 73-75.
Search in Google Scholar
9. Amaral AS, Gaspar LFJ, Bassani-Silva S, Rocha NS: Cytological diagnostic of transmissible venereal tumor in the Botucatu region, Brazil (descriptive study: 1994-2003). RPCV 2007, 99: (551): 167-171.
Search in Google Scholar
10. Thangathurai R, Balasubramaniam GA, Dharmaceelan S, Balachandran P, Srinivasan P, Sivaseelan S, Manohar BM: Cytological diagnosis and its histological correlation in canine transmissible venereal tumour. Vet Arhiv 2008, 78: 369-376.
Search in Google Scholar
11. Marchal T, Chabanne L, Kaplanski C, Rigal D, Magnol JP: Immunophenotype of the canine transmissible venereal tumour. Veterinary Immunology and Immunopathology 1997, 5: l-11.10.1016/S0165-2427(96)05757-1
Search in Google Scholar
12. Mozos E, Mendez A, Gome C, Villamandos I, De Las Mulas MJ, Perez J: Immunohistochemical Characterization of Canine Transmissible Venereal Tumor. Vet Pathol 1996, 33:257-263.10.1177/0300985896033003018740698
Search in Google Scholar
13. Pena L, Nieto AI, Dolores PA, Cuesta P, Castano M: Immunohistochemical detection of Ki-67 and PCNA in canine mammary tumors: relationship to clinical and pathologic variables. J Vet Diagn Invest 1998, 10: 237–246.10.1177/1040638798010003039683072
Search in Google Scholar
14. Kumar A, Sangwan V, Mahajan SK, Singh ND, Singh K, Anand A, Saini NS: Transmissible Venereal Tumor Induced Paraphimosis in Dogs. Journal of Advanced Veterinary Research. 2012, 2: 48-49.
Search in Google Scholar
15. Kennedy KC, Cullen JM, Edwards JF, Goldschmidt MH, Larsen S, Munson L, Nielsen S: Histological Classification of Tumors of the Genital System of Domestic Animals, second series volume IV, World Health Organization, International Histological Classification of Tumors of Domestic Animals,1998: 37-38.
Search in Google Scholar
16. Stockmann D, Ferrari HF, Andrade AL, Lopes RA, Cardoso TC, Luvizotto MCR: Canine Transmissible Venereal Tumors: Aspects Related to Programmed Cell Death, Braz J Vet Pathol, 2011 4(1): 67-75.
Search in Google Scholar

Nasal Transmissible Venereal Tumor In A Jack Russel Terrier Bitch

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