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Influence of plasma on the physical properties of ointments with quercetin Cover

Influence of plasma on the physical properties of ointments with quercetin

Open Access
|Jan 2018

Abstract

Effects of two independent variables - the content of quercetin (0 or 1 or 1.5 or 5 %) and the content of plasma (0 or 2 or 4 or 6 %) - on the organoleptic properties and rheological parameters of model formulations prepared on an amphiphilic base were estimated. The consistency of all ointments was uniform, and the content of quercetin and plasma lay within the predefined range. Tested ointments are non-Newtonian systems. The content of quercetin and plasma was found to have a significant effect on the rheological properties of the ointments. An increase in the content of plasma in ointments was accompanied by a significant increase in their hardness, viscosity and shear stress and a reduction of their spreadability. The best rheological properties were shown by formulation F-3, containing 1.5 % of quercetin and 2 % of plasma.

DOI: https://doi.org/10.1515/acph-2017-0038 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
Language: English
Page range: 569 - 578
Accepted on: Sep 25, 2017
Published on: Jan 11, 2018
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
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© 2018 Beata Szulc-Musioł, Barbara Dolińska, Justyna Kołodziejska, Florian Ryszka, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.