References
- 1. A. M. Stuckey, Breast cancer: epidemiology and risk factors, Clin. Obst. Gynecol. 54 (2011) 96-102; DOI: 10.1097/GRF.0b013e3182080056.10.1097/GRF.0b013e3182080056
- 2. F. C. Thorn, C. Oshiro, S. Marsh, T. Hernandez-Boussard, H. McLeod, T. Klein and B. R. Altman, Doxorubicin pathways: pharmacodynamics and adverse effects, Pharmacogenet. Genom. 21 (2011) 440-446; DOI: 10.1097/FPC.0b013e32833ffb56.10.1097/FPC.0b013e32833ffb56
- 3. A. Jashari, F. Imeri, L. Ballazhi, A. Shabani, B. Mikhova, G. Dräger, E. Popovski and A. Huwiler, Synthesis and cellular characterization of novel isoxazolo- and thiazolohydrazinyldiene-chroman-2,4-diones on cancer and non-cancer cell growth and death, Bioorg. Med. Chem. 22 (2014) 2655-2661; DOI: 10.1016/j.bmc.2014.03.026.10.1016/j.bmc.2014.03.026
- 4. S. Chen, M. Cho, K. Karlsberg, D. Zhou and Y. Yuan, Biochemical and biological characterization of a novel anti-aromatase coumarin derivative, J. Biol. Chem. 279 (2004) 48071-48078; DOI: 10.1074/ jbc.M406847200.10.1074/jbc.M406847200
- 5. L. Woo, A. Purohit, B. Malini, M. Reed and B. Potter, Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates, Chem. Biol. 7 (2000) 773-791; DOI: 10.1016/S1074-5521(00)00023-5.10.1016/S1074-5521(00)00023-5
- 6. M. Musa, J. Cooperwood and M. Khan, A review of coumarin derivatives in pharmacotherapy of breast cancer, Curr. Med. Chem. 15 (2008) 2664-2679; DOI: 10.2174/092986708786242877.10.2174/092986708786242877377264418991629
- 7. S. Kirkiacharian, A. Lormier, H. Chidiack, F. Bouchoux and E. Cérède, Synthesis and binding affinity to human alpha and beta estrogen receptors of various 7-hydroxycoumarins substituted at 4- and 3,4- positions, Farmaco 59 (2004) 981-986; DOI: 10.1016/j.farmac.2004.08.004.10.1016/j.farmac.2004.08.00415598433
- 8. M. Halasi, H. Zhao, H. Dahari, U. G. Bhat, E. B. Gonzalez, A. V. Lyubimo, D. A. Tonetti and A. L. Gartel, Thiazole antibiotics against breast cancer, Cell Cycle 9 (2010) 1214-1217; DOI: 10.4161/ cc.9.6.10955.10.4161/cc.9.6.1095520410687
- 9. J. Shaw, B. Chen, J. P. Bourgault, H. Jiang, K. Narendra, M. Jayshree, A. V. Frederick, M. Joe, B. Kevin, P. Halina, E. Matthew and R. A. Peter, Synthesis and biological evaluation of novel nphenyl-5-carboxamidyl isoxazoles as potential chemotherapeutic agents for colon cancer, Am. J. Biomed. Sci. 4 (2012) 14-25; DOI: 10.5099/aj120100014.10.5099/aj120100014418295325285182
- 10. P. Poma, M. Notarbartolo, M. Labbozzetta, A. Maurici, V. Carina, A. Alaimo, M. Rizzi, D. Simoni and N. D’Alessandro, The antitumor activities of curcumin and of its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 breast cancer cell line: analysis of the possible molecular basis, Int. J. Mol. Med. 20 (2007) 329-335; DOI: 10.3892/ ijmm.20.3.329.
- 11. L. Ballazhi, E. Popovski, A. Jashari, F. Imeri, I. Ibrahimi, B. Mikhova and K. Mladenovska, Potential antiproliferative effect of isoxazolo- and thiazolo coumarin derivatives on breast cancer mediated bone and lung metastases, Acta Pharm. 65 (2015) 53-63; DOI: 10.1515/acph-2015-0002.10.1515/acph-2015-000225781704
- 12. A. Jashari, E. Popovski, B. Mikhova, P. R. Nikolova and L. B. Shivachev, 3-[2-(5-tert-Butyl-1,2-oxazol-3-yl)hydrazinylidene]chroman-2,4-dione, Acta Crystallogr. E69 (2013) o258; DOI: 10.1107/ S1600536813000858.
- 13. L. Ballazhi, F. Imeri, A. Dimovski, A. Jashari, E. Popovski, P. B. Selmani, B. Mikhova, G. Dräger, E. Alili-Idrizi and K. Mladenovska, Synergy of novel coumarin derivatives and tamoxifen in blocking growth and inducing apoptosis of breast cancer cells, Mac. Pharm. Bull. 60 (2014) 35-44.10.33320/maced.pharm.bull.2014.60.01.005
- 14. N. C. Bols, V. R. Dayeh, L. E. J. Lee and K. Schirmer, Use of Fish Cell Lines in the Toxicology and Ecotoxicology of Fish, in Biochemistry and Molecular Biology of Fishes - Environmental Toxicology (Eds. T. P. Mommsen and T. W. Moon), Vol. 6, Elsevier Science, Amsterdam 2005, pp. 43-84.10.1016/S1873-0140(05)80005-0
- 15. R. Hamid, Y. Rotshteyn, L. Rabadi, R. Parikh and P. Bullock, Comparison of alamar blue and MTT assays for high through-put screening, Toxicol. In Vitro 18 (2004) 703-710; DOI: 10.1016/j. tiv.2004.03.012.
- 16. W. F. Deckert and K. H. Remmer, In vitro inhibition of rat and human liver microsomal enzymes by 4-hydroxycoumarin anticoagulants and related compounds, Chem. Biol. Inter. 5 (1972) 255-263; DOI: 10.1016/0009-2797(72)90029-4.10.1016/0009-2797(72)90029-4
- 17. H. Liu, Y. Wang, A. Sharma, R. Mao, N. Jiang, B. Dun and X. J. She, Derivatives containing both coumarin and benzimidazole potently induce caspase-dependent apoptosis of cancer cells through inhibition of PI3K-AKT-mTOR signaling, Anticancer Drugs 26 (2015) 667-677; DOI: 10.1097/ CAD.0000000000000232.10.1097/CAD.000000000000023225811964
- 18. O. Bar-On, M. Shapira and D. D. Hershko, Differential effects of doxorubicin treatment on cell cycle arrest and Skp2 expression in breast cancer cells, Anti-Cancer Drugs 18 (2007) 1113-1121; DOI: 10.1097/CAD.0b013e3282ef4571.10.1097/CAD.0b013e3282ef457117893511
- 19. R. Lüpertz, W. Wätjen, R. Kahl and Y. Chovolou, Dose- and time-dependent effects of doxorubicin on cytotoxicity, cell cycle and apoptotic cell death in human colon cancer cells, Toxicology 271 (2010) 115-121; DOI: 10.1016/j.tox.2010.03.012.10.1016/j.tox.2010.03.01220346999
- 20. A. M. Musa, L. V. Badisa, M. L. Latinwo, J. Cooperwood, A. Sinclair and A. Abdullah, Cytotoxic activity of new acetoxycoumarin derivatives in cancer cell lines, Anticancer Res. 31 (2011) 2017-2022.
- 21. A. Goel, K. A. Prasad, S. V. Parmar, B. Ghosh and N. Saini, 7,8-Dihydroxy-4-methylcoumarin induces apoptosis of human lung adenocarcinoma cells by ROS-independent mitochondrial pathway through partial inhibition of ERK/MAPK signaling, FEBS Lett. 581 (2007) 2447-2454; DOI: 10.1016/j.febslet.2007.04.052.10.1016/j.febslet.2007.04.05217485089
- 22. D. Alesiani, R. Cicconi, M. Mattei, C. Montesano, R. Bei and A. Canini, Cell cycle arrest and differentiation induction by 5,7-dimethoxycoumarin in melanoma cell lines, Int. J. Oncol. 32 (2008) 425-434; DOI: 10.3892/ijo.32.2.425.10.3892/ijo.32.2.425
- 23. F. Haghighi, M. M. Matin, A. R. Bahrami, M. Iranshahi, F. B. Rassouli and A. Haghighitalab, The cytotoxic activities of 7-isopentenyloxycoumarin on 5637 cells via induction of apoptosis and cell cycle arrest in G2/M stage, DARU J. Pharm. Sci. 22 (2014) Article ID: 3 (10 pages); DOI: 10.1186/2008-2231-22-3.10.1186/2008-2231-22-3389859824393601
- 24. C. Barthomeuf, S. Lim, M. Iranshahi and P. Chollet, Umbelliprenin from Ferula szowitsiana inhibits the growth of human M4Beu metastatic pigmented malignant melanoma cells through cell-cycle arrest in G1 and induction of caspase-dependent apoptosis, Phytomedicine 15 (2008) 103-111; DOI: 10.1016/j.phymed.2007.04.001.10.1016/j.phymed.2007.04.00117689942
- 25. Y. J. Chuang, F. Y. Huang, F. H. Lu, C. H. Ho, S. J. Yang, M. T. Li, W. N. Chang and G. J. Chung, Coumarin induces cell cycle arrest and apoptosis in human cervical cancer HeLa cells through a mitochondria- and caspase-3 dependent mechanism and NF-kappaB down-regulation, In Vivo 21 (2007) 1003-1010.
- 26. M. Kielbus, K. Skalicka-Wozniak, A. Grabarska, W. Jeleniewicz, M. Dmoszynska-Graniczka, A. Marston, K. Polberg, P. Gawda, J. Klatka and A. Stepulak, 7-Substituted coumarins inhibit proliferation and migration of laryngeal cancer cells in vitro, Anticancer Res. 33 (2013) 4347-4356.
- 27. D. Yang, T. Gu, T. Wang, Q. Tang and C. Ma, Effects of osthole on migration and invasion in breast cancer cells, Biosci. Biotechnol. Biochem. 74 (2010) 1430-1434; DOI: 1271/bbb.100110.10.1271/bbb.100110
- 28. W. F. van der Giesen and L. H. Janssen, Influence of ionization and ion-pair formation on lipophilicity of some 4-hydroxy-coumarin derivatives in the octanol-water system, Int. J. Pharm. 12 (1982) 231-249; DOI: 10.1016/0378-5173(82)90122-3.10.1016/0378-5173(82)90122-3
- 29. H. Schönherr and T. Cernak, Profound methyl effects in drug discovery and a call for new C-H methylation reactions, Angew. Chem. Int. Ed. Engl. 52 (2013) 12256-12267; DOI: 10.1002/ anie.201303207.10.1002/anie.20130320724151256
- 30. S. C. Leung, S. S. Leung, J. R. Tirado and L. W. Jorgensen, Methyl effects on protein-ligand binding, J. Med. Chem. 55 (2012) 4489-4500; DOI: 10.1021/jm3003697. 10.1021/jm3003697335332722500930