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Modulatory effects of rutin on the expression of cytochrome P450s and antioxidant enzymes in human hepatoma cells Cover

Modulatory effects of rutin on the expression of cytochrome P450s and antioxidant enzymes in human hepatoma cells

By: Sedar Karakurt  
Open Access
|Oct 2016

References

  1. 1. L. A. Torre, F. Bray, R. L. Siegel, J. Ferlay, J. Lortet-Tieulent and A. Jemal, Global cancer statistics, 2012, Cancer J. Clin. 65 (2015) 87-108; DOI: 10.3322/caac.21262.10.3322/caac.21262
  2. 2. M. Balbi, V. Donadon, M. Ghersetti, S. Grazioli, G. D. Valentina, R. Gardenal, M. D. Mas, P. Casarin, G. Zanette, C. Miranda and P. Cimarosti, Alcohol and HCV chronic infection are risk cofactors of type 2 diabetes mellitus for hepatocellular carcinoma in Italy, Int. J. Environ. Res. Public Health 7 (2010) 1366-1378; DOI: 10.3390/ijerph7041366.10.3390/ijerph7041366
  3. 3. X. Zhang and H. G. Ding, Key role of hepatitis B virus mutation in chronic hepatitis B development to hepatocellular carcinoma, World J. Hepatol. 7 (2015) 1282-1286; DOI: 10.4254/wjh.v7.i9.1282.10.4254/wjh.v7.i9.1282
  4. 4. P. C. Hollman and M. B. Katan, Absorption, metabolism and health effects of dietary flavonoids in man, Biomed. Pharmacother. 51 (1997) 305-310; DOI: 10.1016/S0753-3322(97)88045-6.10.1016/S0753-3322(97)88045-6
  5. 5. E. Middleton, C. Kandaswami and T. C. Theoharides, The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer, Pharmacol. Rev. 52 (2000) 673-751.
  6. 6. G. Williamson and C. Manach, Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies, Am. J. Clin. Nutr. 81 (2005) 243S-255S.
  7. 7. B. A. Graf, C. Ameho, G. G. Dolnikowski, P. E. Milbury, C. Y. Chen and J. B. Blumberg, Rat gastrointestinal tissues metabolize quercetin, J. Nutr. 136 (2006) 39-44.10.1093/jn/136.1.3916365056
  8. 8. S. Scholz and G. Williamson, Interactions affecting the bioavailability of dietary polyphenols in vivo, Int. J. Vitam. Nutr.Res. 77 (2007) 224-235; DOI: 10.1024/0300-9831.77.3.224.10.1024/0300-9831.77.3.22418214024
  9. 9. V. A. Kostyuk, A. I. Potapovich, T. V. Kostyuk and M. G. Cherian, Metal complexes of dietary flavonoids: evaluation of radical scavenger properties and protective activity against oxidative stress in vivo, Cell. Mol. Biol. (Noisy-le-grand) 53 (2007) 62-69; DOI: 10.1170/T776.
  10. 10. K. Song, J. Y. Na, S. Kim and J. Kwon, Rutin upregulates neurotrophic factors resulting in attenuation of ethanol-induced oxidative stress in HT22 hippocampal neuronal cells, J. Sci. Food Agric. 95 (2015) 2117-2123; DOI: 10.1002/jsfa.6927.10.1002/jsfa.692725251136
  11. 11. B. L. Santos, A. R. Silva, B. P. Pitanga, C. S. Sousa, M. S. Grangeiro, B. O. Fragomeni, P. L. Coelho, M. N. Oliveira, N. J. Menezes-Filho, M. F. Costa, R. S. El-Bachá, E. S. Velozo, G. P. Sampaio, S. M. Freire, M. Tardy and S. L. Costa, Antiproliferative, proapoptotic and morphogenic effects of the flavonoid rutin on human glioblastoma cells, Food Chem. 127 (2011) 404-411; DOI: 10.1016/j.foodchem. 2010.12.13.
  12. 12. N. Ihme, H. Kiesewetter, F. Jung, K. H. Hoffmann, A. Birk, A. Müller and K. I. Grützner, Leg oedema protection from a buckwheat herb tea in patients with chronic venous insufficiency: a single- centre, randomised, double-blind, placebo-controlled clinical trial, Eur. J. Clin. Pharmacol. 50 (1996) 443-447; DOI: 10.1007/s002280050138.10.1007/s0022800501388858269
  13. 13. S. Okonogi, R. Khonkarn, S. Mankhetkorn, F. M. Unger and H. Viernstein, Antioxidant activity and cytotoxicity of Cyrtosperma johnstonii extracts on drug sensitive and resistant leukemia and small cell lung carcinoma cells, Pharm. Biol. 51 (2013) 329-338; DOI: 10.3109/13880209.2012.729064.10.3109/13880209.2012.72906423153173
  14. 14. H. J. You, H. J. Ahn and G. E. Ji, Transformation of rutin to antiproliferative quercetin-3-glucoside by Aspergillus niger, J. Agric. Food Chem. 58 (2010) 10886-10892; DOI: 10.1021/jf102871g.10.1021/jf102871g20886886
  15. 15. F. P. Guengerich, Cytochrome P-450 3A4: regulation and role in drug metabolism, Annu. Rev. Pharmacol. Toxicol. 39 (1999) 1-17; DOI: 10.1146/annurev.pharmtox.39.1.1.10.1146/annurev.pharmtox.39.1.1
  16. 16. U. M. Zanger and M. Schwab, Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation, Pharmacol. Ther. 138 (2013) 103-141; DOI: 10.1016/j.pharmthera.2012.12.007.10.1016/j.pharmthera.2012.12.007
  17. 17. K. Ohkura, Y. Kawaguchi, Y. Watanabe, Y. Masubuchi, Y. Shinohara and H. Hori, Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket, Anticancer Res. 29 (2009) 935-942.
  18. 18. E. Arinç, D. Yilmaz and A. Bozcaarmutlu, Mechanism of inhibition of CYP1A1 and glutathione S-transferase activities in fish liver by quercetin, resveratrol, naringenin, hesperidin, and rutin, Nutr. Cancer 67 (2015) 137-144; DOI: 10.1080/01635581.2015.965335.10.1080/01635581.2015.965335
  19. 19. T. Fujimura, S. Takahashi, T. Urano, T. Tanaka, W. Zhang, K. Azuma, K. Takayama, D. Obinata, T. Murata, K. Horie-Inoue, T. Kodama, Y. Ouchi, Y. Homma and S. Inoue, Clinical significance of steroid and xenobiotic receptor and its targeted gene CYP3A4 in human prostate cancer, Cancer Sci. 103 (2012) 176-180; DOI: 10.1111/j.1349-7006.2011.02143.x.10.1111/j.1349-7006.2011.02143.x
  20. 20. J. C. Stevens, R. N. Hines, C. Gu, S. B. Koukouritaki, J. R. Manro, P. J. Tandler and M. J. Zaya, Developmental expression of the major human hepatic CYP3A enzymes, J. Pharmacol. Exp. Ther. 307 (2003) 573-582; DOI: 10.1124/jpet.103.054841.10.1124/jpet.103.054841
  21. 21. H. P. Ciolino, P. J. Daschner and G. C. Yeh, Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially, Biochem. J. 340 (1999) 715-722; DOI: 10.1042/bj3400715.10.1042/bj3400715
  22. 22. R. Vrba, R. Aujeský and C. Neoral, Results of limited resection of carcinoma of the gastroesophageal junction, Rozhl. Chir. 91 (2012) 368-372.
  23. 23. Mohammadi-Bardbori, J. Bengtsson, U. Rannug, A. Rannug and E. Wincent, Quercetin, resveratrol, and curcumin are indirect activators of the aryl hydrocarbon receptor (AHR), Chem. Res. Toxicol. 25 (2012) 1878-1884; DOI: 10.1021/tx300169e. 10.1021/tx300169e
  24. 24. L. Rongrui, H. Na, L. Zongfang, J. Fanpu and J. Shiwen, Epigenetic mechanism involved in the HBV/HCV-related hepatocellular carcinoma tumorigenesis, Curr. Pharm. Des. 20 (2014) 1715-1725; DOI: 10.2174/13816128113199990533.10.2174/13816128113199990533
  25. 25. M. Kiran, Y. K. Chawla and J. Kaur, Methylation profiling of tumor suppressor genes and oncogenes in hepatitis virus-related hepatocellular carcinoma in northern India, Cancer Genet. Cytogenet. 195 (2009) 112-119; DOI: 10.1016/j.cancergencyto.2009.06.021.10.1016/j.cancergencyto.2009.06.021
  26. 26. D. Ross, J. K. Kepa, S. L. Winski, H. D. Beall, A. Anwar and D. Siegel, NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms, Chem. Biol. Interact. 129 (2000) 77-97; DOI: 10.1016/S0009-2797(00)00199-X.10.1016/S0009-2797(00)00199-X
  27. 27. P. Joseph, T. Xie, Y. Xu and A. K. Jaiswal, NAD(P)H:quinone oxidoreductase1 (DT-diaphorase): expression, regulation, and role in cancer, Oncol. Res. 6 (1994) 525-532.
  28. 28. E. A. Rosvold, K. A. McGlynn, E. D. Lustbader and K. H. Buetow, Identification of an NAD(P) H:quinone oxidoreductase polymorphism and its association with lung cancer and smoking, Pharmacogenetics 5 (1995) 199-206.
  29. 29. Y. Fan, D. Hu, B. Feng and W. Wang, The NQO1 C609T polymorphism and hepatocellular carcinoma risk, Tumour Biol. 35 (2014) 7343-7350; DOI: 10.1007/s13277-014-1712-8.10.1007/s13277-014-1712-824532470
  30. 30. H. Akkiz, S. Bayram, A. Bekar, E. Akgöllü, Y. Ülger, B. Y. Kaya, M. Sandikçi and B. Özdil, No association of NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism and risk of hepatocellular carcinoma development in Turkish subjects, Asian Pac. J. Cancer Prev. 11 (2010) 1051-1058.
  31. 31. M. Belinsky and A. K. Jaiswal, NAD(P)H:quinone oxidoreductase1 (DT-diaphorase) expression in normal and tumor tissues, Cancer Metastasis Rev. 12 (1993) 103-117; DOI: 10.1007/BF00689804 10.1007/BF006898048375015
DOI: https://doi.org/10.1515/acph-2016-0046 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
Language: English
Page range: 491 - 502
Accepted on: Jul 27, 2016
Published on: Oct 15, 2016
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
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© 2016 Sedar Karakurt, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.