Skip to main content
Have a personal or library account? Click to login
Physicochemical characterization and dissolution studies of acyclovir solid dispersions with Pluronic F127 prepared by the kneading method Cover

Physicochemical characterization and dissolution studies of acyclovir solid dispersions with Pluronic F127 prepared by the kneading method

Acta Pharmaceutica
Volume 66 (2016): Issue 1 (March 2016)
By: ,  ,   and    
Open Access
|Mar 2016
References

References

  1. 1. C. Cernik, K. Gallina and R. T. Brodell, The treatment of herpes simplex infections: an evidence-based review,(2008) 1137–1144; DOI: 10.1001/archinte.168.11.1137.
    Open DOISearch in Google Scholar
  2. 2. K. S. Erlich, Management of herpes simplex and varicella-zoster virus infections,(1997) 211–215.
    Search in Google Scholar
  3. 3. D. M. Thappa,, 3rd ed., Elsevier, Gurgaon 2009, pp. 350–351.
    Search in Google Scholar
  4. 4. J. Arnal, I. Gonzalez-Alvarez, M. Bermejo, G. L. Amidon, H. E. Junginger, S. Kopp, K. K. Midha, V. P. Shah, S. Stavchansky, J. B. Dressman and D. M. Barends, Biowaiver monographs for immediate release solid oral dosage forms: acyclovir,(2008) 5061–5073; DOI: 10.1002/jps.21392.
    Open DOISearch in Google Scholar
  5. 5. R. Sankar and S. Jain, Approaches for enhancing the bioavailability of acyclovir: a critical review,.(2013) 623–633.
    Search in Google Scholar
  6. 6. K. M. Lutker, R. Quinones, J. Xu, A. Ramamoorthy and A. J. Matzger, Polymorphs and hydrates of acyclovir,.(2011) 949–963; DOI: 10.1002/jps.22336.
    Open DOISearch in Google Scholar
  7. 7. K. Terada, H. Kurobe, M. Ito, Y. Yoshihashi, E. Yonemochi, K. Fujii and H. Uekusa, Polymorphic transformation behavior of acyclovir based on the thermodynamics and crystallography,(2013) 1261–1267; DOI: 10.1007/s10973-013-3140-1.
    Open DOISearch in Google Scholar
  8. 8. A. Kristl, S. Srcic, F. Vrecer, B. Sustar and D. Vojnovic, Polymorphism and pseudopolymorphism: influencing the dissolution properties of the guanine derivative acyclovir,(1996) 231–235; DOI: 10.1016/0378-5173(96)04601-7.
    Open DOISearch in Google Scholar
  9. 9. Y. T. Sohn and S. H. Kim, Polymorphism and pseudopolymorphism of acyclovir,(2008) 231–234; DOI: 10.1007/s12272-001-1146-x.
    Open DOISearch in Google Scholar
  10. 10. P. K. Ghosh, R. J. Majithiya, M. L. Umrethia and R. S. R. Murthy, Design and development of microemulsion drug delivery system of acyclovir for improvement of oral bioavailability,(2006) 172–177; DOI: 10.1208/pt070377.
    Open DOISearch in Google Scholar
  11. 11. C. Von Plessing Rossel, J. S. Carreño, M. Rodríguez-Baeza and J. B. Alderete, Inclusion complex of the antiviral drug acyclovir with cyclodextrin in aqueous solution and in solid phase,(2000) 749–752; DOI: 10.1590/S0100-40422000000600007.
    Open DOISearch in Google Scholar
  12. 12. T. Masuda, Y. Yoshihashi, E. Yonemochi, K. Fujii, H. Uekusa and K. Terada, Cocrystallization and amorphization induced by drug-excipient interaction improves the physical properties of acyclovir,(2012) 160–169; DOI: 10.1016/j.ijpharm.2011.10.046.
    Open DOISearch in Google Scholar
  13. 13. D. Patel and K. K. Sawant, Oral bioavailability enhancement of acyclovir by self-microemulsifying drug delivery systems (SMEDDS),(2007) 1318–1326; DOI: 10.1080/03639040701385527.
    Open DOISearch in Google Scholar
  14. 14. A. Kushwaha, S. K. Prajapati and B. Sharma, Comparative study of acyclovir solid dispersion for bioavailability enhancement,(2011) 179–201.
    Search in Google Scholar
  15. 15. R. Cortesi and E. Esposito, Acyclovir delivery systems,(2008) 1217–1230; DOI: 10.1517/17425240802450340.
    Open DOISearch in Google Scholar
  16. 16. A. Kushwaha, Solid dispersion: an approach to enhance the dissolution rate of acyclovir,(2012) 291–296.
    Search in Google Scholar
  17. 17. N. Sachan, S. Pushkar, S. S. Solanki and D. S. Bhatere, Enhancement of solubility of acyclovir by solid dispersion and inclusion complexation methods,(2010) 857–864.
    Search in Google Scholar
  18. 18. B. Karolewicz, M. Gajda, A. Owczarek, J. Pluta and A. Górniak, Physicochemical and dissolution studies of simvastatin solid dispersions with Pluronic F127,(2014) 589–594; DOI: 10.1691/ph.2014.3217.
    Search in Google Scholar
  19. 19. B. Karolewicz, A. Górniak, A. Owczarek, E. Żurawska-Płaksej, A. Piwowar and J. Pluta, Thermal, spectroscopic, and dissolution studies of ketoconazole–Pluronic F127 system,(2014) 2487–2493; DOI: 10.1007/s10973-014-3661-2.
    Open DOISearch in Google Scholar
  20. 20. G. A. Shazly, M. A. Ibrahim, M. M. Badran and K. M. A. Zoheir, Utilizing Pluronic F-127 and Gelucire 50/13 solid dispersions for enhanced skin delivery of flufenamic acid,(2012) 299–307; DOI: 10.1002/ddr.21013.
    Open DOISearch in Google Scholar
  21. 21. P. Kumar, C. Mohan, M. K. S. U. Shankar and M. Gulati, Physiochemical characterization and release rate studies of solid dispersions of ketoconazole with Pluronic F127 and PVP K-30,(2011) 685–694.
    Search in Google Scholar
  22. 22. N. Kolašinac, K. Kachrimanis, I. Homšek, B. Grujič, Z. Ðurič and S. Ibrič, Solubility enhancement of desloratadine by solid dispersion in poloxamers,(2012) 161–170; DOI: 10.1016/j.ijpharm.2012.06.060.
    Open DOISearch in Google Scholar
  23. 23, 8th ed., European Directorate for the Quality of Medicines & Healthcare, Strasbourg 2014, pp. 331–333.
    Search in Google Scholar
  24. 24. D. Q. M. Craig, The mechanisms of drug release from solid dispersions in water-soluble polymers,(2002) 131–144; DOI: 10.1016/S0378-5173(01)00891-2.
    Open DOISearch in Google Scholar
  25. 25. T. L. Threlfall, Analysis of organic polymorphs. A review,(1995) 2435–2460; DOI: 10.1039/AN9952002435.
    Open DOISearch in Google Scholar
  26. 26. M. G. Issa and H. G. Ferraz, Intrinsic dissolution as a tool for evaluating drug solubility in accordance with the Biopharmaceutics Classification System,(2011) 6–13; DOI: 10.14227/DT180311P6.
    Open DOISearch in Google Scholar
  27. 27. L. X. Yu, A. S. Carlin, G. L. Amidon and A. S. Hussain, Feasibility studies of utilizing disk intrinsic dissolution rate to classify drugs,(2004) 221–227; DOI: 10.1016/j.ijpharm.2003.10.016.
    Open DOISearch in Google Scholar
  28. 28. L. X. Yu, G. L. Amidon, J. E. Polli, H. Zhao, M. U. Mehta, D. P. Conner, V. P. Shah, L. J. Lesko, M. Chen, V. H. L. Lee and A. S. Hussain, Biopharmaceutics classification system: The scientific basis for biowaiver extensions,(2002) 921–925; DOI: 10.1023/A:1016473601633.
    Open DOISearch in Google Scholar
  29. 29. P. Zakeri-Milani, M. Barzegar-Jalali, M. Azimi and H. Valizadeh, Biopharmaceutical classification of drugs using intrinsic dissolution rate (IDR) and rat intestinal permeability,.(2009) 102–106; DOI: 10.1016/j.ejpb.2009.04.015.
    Open DOISearch in Google Scholar
  30. 30. M. El-Badry, M. A. Hassan, M. A. Ibrahim and H. Elsaghir, Performance of Poloxamer 407 as hydrophilic carrier on the binary mixtures with nimesulide,(2013) 1137–1150.
    Search in Google Scholar
DOI: https://doi.org/10.1515/acph-2016-0008 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
Journal RSS Feed
Language: English
Page range: 119 - 128
Accepted on: Sep 28, 2015
Published on: Mar 7, 2016
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Keywords:
acyclovir,
Pluronic F127,
solid dispersions,
physical mixtures,
kneading,
dissolution improvement
Related subjects:
Pharmacy,
Pharmacy, other

© 2016 Bożena Karolewicz, Karol Nartowski, Janusz Pluta, Agata Górniak, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 66 (2016): Issue 1 (March 2016)
Previous article
Next article