Nitrones: not only extraordinary spin traps, but also good nitric oxide sources in vivo
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References
- 1. J. Ahn and J. Kim, Mechanisms and consequences of inflammatory signaling in the myocardium, Curr. Hypertens. Rep. 14 (2012) 510-516; DOI: 10.1007/s11906-012-0309-0.
- 2. D. M. Ansley and B. Wang, Oxidative stress and myocardial injury in the diabetic heart, J. Pathol. 229 (2013) 232-241; DOI: 10.1002/path.4113.
- 3. A . M. Walters, G. A. Porter and P. S. Brookes, Mitochondria as a drug target in ischemic heart disease and cardiomyopathy, Circ. Res. 111 (2012) 1222-1236; DOI : 10.1161/CIR CRE SAHA.112.265660.
- 4. C. Sai and L. Shuzhuang, The Na+/Ca2+ exchanger in cardiac ischemia/reperfusion injury, Med. Sci. Monit. 18 (2012) 161-165; DOI : 10.12659/MSM.883533.
- 5. J. M. Pilcher, P. Young, M. Weatherall, I. Rahman, R. S. Bonser and R. W. Beasley, A systematic review and meta-analysis of the cardioprotective effects of remote ischaemic preconditioning in open cardiac surgery, J. R. Soc. Med. 105 (2012) 436-445; DOI: 10.1258/jrsm.2012.120049.
- 6. D. J. Hausenloy and D. M. Yellon, Reperfusion injury salvage kinase signalling: taking a RI SK for cardioprotection, Heart Fail. Rev. 12 (2007) 217-234; DOI: 10.1007/s10741-007-9026-1.
- 7. R . Rodrigo, J. C. Prieto and R. Castillo, Cardioprotection against ischaemia/reperfusion by vitamins C and E plus n-3 fatty acids: molecular mechanisms and potential clinical applications, Clin. Sci. (Lond). 124 (2013) 1-15; DOI : 10.1042/CS20110663.
- 8. R . Rodrigo, J. Vinay, R. Castillo, M. Cereceda, R. Asenjo and J. Zamorano, Use of vitamins C and E as a prophylactic therapy to prevent postoperative atrial fibrillation, Int. J. Cardiol. 138 (2010) 221-228; DOI : 10.1016/j.ijcard.2009.04.043.
- 9. M. G. Andreassi, Coronary atherosclerosis and somatic mutations: an overview of the contributive factors for oxidative DNA damage, Mutat. Res. 543 (2003) 67-86; DOI : 10.1016/S1383-5742 (02)00089-3.
- 10. H. A. Kim, A. A. Miller, G. R. Drummond, A. G. Thrift, T. V. Arumugam and T. G. Phan, Vascular cognitive impairment and Alzheimer’s disease: role of cerebral hypoperfusion and oxidative stress, Naunyn-Schmiedeberg. Arch. Pharmacol. 385 (2012) 953-959; DOI: 10.1007/s00210-012-0790-7.
- 11. L . Kuo, N. Thengchaisri and T. W. Hein, Regulation of coronary vasomotor function by reactive oxygen species, Mol. Med. Ther. 1 (2012) 1-4; DOI: 10.4172/2324-8769.1000101.
- 12. A . S. Simon, V. Chithra, A. Vijayan, R. D. Dinesh and T. Vijayakumar, Altered DNA repair, oxidative stress and antioxidant status in coronary artery disease, J. Biosci. 38 (2013) 385-389; DOI: 10.1007/s12038-013-9313-z.
- 13. E . Bor-Seng-Shu, W. S. Kita, E. G. Figueiredo, W. S. Paiva, E. T. Fonoff, M. J. Teixeira and R. B. Panerai, Cerebral hemodynamics: concepts of clinical importance, Arq. Neuropsiquiatr. 70 (2012) 352-356.
- 14. F. Folli, D. Corradi, P. Fanti, A. Davalli, A. Paez and A. Giaccari, The role of oxidative stress in the pathogenesis of type 2 diabetes mellitus micro- and macrovascular complications: avenues for a mechanistic-based therapeutic approach, Curr. Diabetes Rev. 7 (2011) 313-324; DOI: 10.2174/ 157339911797415585.
- 15. N. A. Terpolilli, M. A. Moskowitz and N. Plesnila, Nitric oxide: considerations for the treatment of ischemic stroke, J. Cereb. Blood Flow Metab. 32 (2012) 1332-1346; DOI: 10.1038/jcbfm.2012.12.
- 16. N. Toda and H. Toda, Coronary hemodynamic regulation by nitric oxide in experimental animals: recent advances, Eur. J. Pharmacol. 667 (2011) 41-49; DOI: 10.1016/j.ejphar.2011.06.028.
- 17. M . R. Macleod, H. B. van der Worp, E. S. Sena, D. W. Howells, U. Dirnagl and G. A. Donnan, Evidence for the efficacy of NXY-059 in experimental focal cerebral ischaemia is confounded by study quality, Stroke 39 (2008) 2824-2829; DOI : 10.1161/STROKEA HA.108.515957.
- 18. R . A. Floyd, K. Hensley, M. J. Forster, J. A. Kelleher-Anderson and P. L. Wood, Nitrones as neuroprotectans and antiaging drugs, Ann. N. Y. Acad. Sci. 959 (2002) 321-329; DOI: 10.1111/j.1749-6632.2002.
- 19. B . Kalyanaraman, J. Joseph and S. Parthasarathy, The spin trap, alpha-phenyl N-tert-butylnitrone, inhibits the oxidative modification of low density lipoprotein, FEBS. Lett. 280 (1991) 17-20; DOI: 10.1016/0014-5793(91)80194-8.
- 20. E . G. Janzen, R. A. Towner and S. Yamashiro, The effect of phenyl tert-butyl nitrone (PBN) on CC l4-induced rat liver injury detected by proton magnetic resonance imaging (MRI) in vivo and electron microscopy (EM), Free Radic. Res. Commun. 9 (1990) 325-335; DOI: 10.3109/10715769009145691.
- 21. M . Thirumalaikumar, S. Sivakolunthu, S. Muthusubramanian, P. Mohan and S. Sivasubramanian, Synthesis, characterization and antimicrobial studies of metal (II ) bis-chelates and mixed-ligand complexes of alpha-(2-hydroxyphenyl)-N-(1-phenyl-2-nitroethyl)nitrone, Boll. Chim. Farm. 35 (1999) 207-210.
- 22. K . T. Knecht and R. P. Mason, In vivo spin trapping of xenobiotic free radical metabolites, Arch. Biochem. Biophys. 303 (1993) 185-194; DOI: 10.1006/abbi.1993.1272.
- 23. S. Kuroda, R. Tsuchidate, M. L. Smith, K. R. Maples and B. K. Siesjo, Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat, J. Cereb. Blood Flow Metab. 9 (1999) 623-625; DOI: 10.1097/00004647-199907000-00008.
- 24. L . A. Reinke, D. R. Moore, C. M. Hague and P. B. McCay, Metabolism of ethanol to 1-hydroxyethyl radicals in rat liver microsomes: comparative studies with three spin trapping agents, Free Radic. Res. 21 (1994) 213-222; DOI: 10.3109/10715769409056573.
- 25. M . D. Croitoru, I. Fülöp, M. C. Pop, T. Dergez, B. Mitroi, M. T. Dogaru and B. Tőkés, Nitrones are able to release nitric oxide in aqueous environment under hydroxyl free radical attack, Nitric oxide 25 (2011) 309-315; DOI: 10.1016/j.niox.2011.05.007.
- 26. R . Camehn and K. Rehse, New NO donors with antithrombotic and vasodilating activities, N-(1- cyanocyclohexyl)-C-phenylnitrones and glyoxaldinitones, Arch. Pharm. Pharm. Med. Chem. 333 (2000) 130-134; DOI : 10.1002/(SICI)1521-4184(20005)333:53.0.CO;2-D.
- 27. W. Chamulitrat, S. J. Jordant, R. P. Mason, K. Saito and R. G. Cutler, Nitric oxide formation during light-induced decomposition of phenyl-N-tert-butylnitrone, J. Biol. Chem. 268 (1993) 11520-11527.
- 28. M. D. Croitoru, Nitrite and nitrate can be accurately measured in vegetal and animal samples using an HPLC-UV/VIS technique, J. Chromatogr. B 911 (2012) 154-161; DOI: 10.1016/j.jchromb. 2012.11.006.
- 29. P. A. Lapchak, D. F. Chapman and J. A. Zivin, Pharmacological effects of the spin trap agents N-tbutyl- phenylnitrone (PBN) and 2,2,6, 6-tetramethylpiperidine-N-oxyl (TEMPO) in a rabbit thromboembolic stroke model: combination studies with the thrombolytic tissue plasminogen activator, Stroke 32 (2001) 147-153; DOI : 10.1161/01.STR .32.1.147.
- 30. M. D. Croitoru, I. Fülöp, E. Fogarasi and D. L. Muntean, Is nitrate a good biomarker of the nitric oxide status?, Rev. Romana Med. Lab. 23 (2015) 127-136; DOI: 10.1515/rrlm-2015-0001.
Language: English
Page range: 413 - 426
Accepted on: Jul 13, 2015
Published on: Dec 17, 2015
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year
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© 2015 Mircea Dumitru Croitoru, Hermina Iulia Petkes, Ibolya Fülöp, Remus Cotârlan, Oana Elena Şerban, Titica Maria Dogaru, Şerban Andrei Gâz Florea, Béla Tőkés, Cornelia Majdik, published by Croatian Pharmaceutical Society
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