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Novel 4-aminoquinazoline derivatives as new leads for anticancer drug discovery Cover

Novel 4-aminoquinazoline derivatives as new leads for anticancer drug discovery

Acta Pharmaceutica
Volume 65 (2015): Issue 3 (September 2015)
By:  and    
Open Access
|Sep 2015
References

References

  1. 1. S. B. Mhaske and N. P. Argade, The chemistry of recently isolated naturally occurring quinazolinone alkaloids,(2006) 9787–9826; DOI: 10.1016/j.tet.2006.07.098.
    Open DOISearch in Google Scholar
  2. 2. N. J. Liverton, D. J. Armstrong, D. A. Claremon, D. C. Remy, J. J. Baldwin, R. J. Lynch, G. Zhang and R. J. Gould, Nonpeptide glycoprotein IIb/IIIa inhibitors: Substituted quinazolinediones and quinazolinones as potent fibrinogen receptor antagonists,.(1998) 483–486; DOI: 10.1016/S0960-894X(98)00047-X.
    Open DOISearch in Google Scholar
  3. 3. W. Zhang, J. P. Mayer, S. E. Hall and J. A. Weigel, A polymer-bound iminophosphorane approach for the synthesis of quinolones,(2001) 255–256; DOI: 10.1021/cc000113e.
    Open DOISearch in Google Scholar
  4. 4. R. J. Griffin, S. Srinivasan, K. Bowman, A. H. Calvert, N. J. Curtin, D. R. Newell, L. C. Pemberton and B. T. Golding, Resistance-modifying agents. 5. Synthesis and biological properties of quinazolinone inhibitors of the DNA repair enzyme poly (ADP-ribose) polymerase (PARP),(1998) 5247–5256; DOI: 10.1021/jm980273t.
    Open DOISearch in Google Scholar
  5. 5. A. N. Hughes, I. Rafi, M. J. Griffin, H. A. Calvert, D. R. Newell, J. A. Calvrte, A. Johnston, N. Clendeninn and A. V. Boddy, Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days,(1999) 111–118.
    Search in Google Scholar
  6. 6. E. Hamel, C. M. Lin, J. Plowman, H. K. Wang, K. H. Lee and K. D. Paull, Antitumor 2,3-dihydro-2-(aryl)-4(1)-quinazolinone derivatives: Interactions with tubulin,.(1996) 53–59; DOI: 10.1016/0006-2952(95)02156-6.
    Open DOISearch in Google Scholar
  7. 7. S. H. Hwang, A. Rait, K. F. Pirollo, Q. Zhou, V. M. Yenugonda, G. M. Chinigo, M. L. Brown and E. H. Chang, Tumor-targeting nanodelivery enhances the anticancer activity of a novel quinazolinone analogue,(2008) 559–568; DOI: 10.1158/1535-7163.MCT-07-0548.
    Open DOISearch in Google Scholar
  8. 8. S. K. Kundu, M. P. D. Mahindaratne, M. V. Quintero, A. Bao and G. R. Negrete, One-pot reductive cyclization to antitumor quinazoline precursors,2008 (2) 33–42.
    Open DOISearch in Google Scholar
  9. 9. M. H. Cohen, J. R. Johnson, Y. F. Chen, R. Sridhara and R. Pazdur, FDA drug approval summary: Erlotinib (Tarceva) tablets,(2005) 461–466; DOI: 10.1634/theoncologist.10-7-461.
    Open DOISearch in Google Scholar
  10. 10. K. Abouzid and S. Shouman, Design, synthesis and in vitro antitumor activity of 4-aminoquino-line and 4-aminoquinazoline derivatives targeting EGFR tyrosine kinase,.(2008) 7543–7551; DOI: 10.1016/j.bmc.2008.07.038.
    Open DOISearch in Google Scholar
  11. 11. A. Witt and J. Bergman, Recent developments in the field of quinazoline chemistry,.(2003) 659–677; DOI: /10.2174/1385272033486738.
    Open DOISearch in Google Scholar
  12. 12. H. Wong and A. Gansan, Total synthesis of the fumiquinazoline alkaloids: Solution-phase studies,.(2003) 1022–1039; DOI: /10.1021/jo9914364.
    Search in Google Scholar
  13. 13. J. P. Micheal, Quinoline, quinazoline and acridone alkaloids,.(2003) 543–559.
    Open DOISearch in Google Scholar
  14. 14. M. M. Ghorab, M. S. Alsaid and R. K. Arafa, Design, synthesis and potential anti-proliferative activity of some novel 4-aminoquinoline derivatives,(2014) 285–297; DOI: 10.2478/acph-2014-0030.
    Open DOISearch in Google Scholar
  15. 15. M. M. Ghorab, F. A. Ragab, S. I. Alqasoumi, A. M. Alafeefy and S. A. Aboulmagd, Synthesis of some new pyrazolo [3, 4-d] pyrimidine derivatives of expected anticancer and radioprotective activity,(2010) 171–178; DOI: 10.1016/j.bmc.–2013.11.042.
    Search in Google Scholar
  16. 16. M. M. Ghorab, H. I. Zienab, A. Mohamad and A. A. Radwan, Synthesis, antimicrobial evaluation and molecular modelling of novel sulfonamides carrying a biologically active quinazoline nucleus,(2013) 660–670; DOI: 10.1007/s12272-013-0094-6.
    Open DOISearch in Google Scholar
  17. 17. M. M. Ghorab, H. I. Zienab, A. A. Radwan and A. Mohamad, Synthesis and pharmacophore modeling of novel quinazolines bearing a biologically active sulfonamide moiety,.(2013) 1–18; DOI: 10.2478/acph-2013-0006.
    Open DOISearch in Google Scholar
  18. 18. M. M. Ghorab, F. A. Ragab, H. I Heiba and M. G. El-Gazzar, Synthesis, in vitro anticancer screening and radiosensitizing evaluation of some new 4-[3-(substituted)thioureido]-N-(quinoxalin-2-yl)-benzenesulfonamide derivatives,(2011) 415–425; DOI: 10.2478/v10007-011-0040-4.
    Open DOISearch in Google Scholar
  19. 19. M. M. Ghorab, F. A. Ragab, H. I. Hieba, H. A. Yousef and M. G. El-Gazzar, Synthesis of novel pyrazole and pyrimidine derivatives bearing sulfonamide moiety as antitumor and radiosensitizing agents,(2012) 1376–1383; DOI: 10.1007/s00044-013-0721-2
    Open DOISearch in Google Scholar
  20. 20. M. S. Al-Dosari, M. M. Ghorab, M. S. Alsaid, Y. M. Nissan and A. B. Ahmed, Synthesis and anti-cancer activity of some novel trifluoromethylquinolines carrying a biologically active benzene-sulfonamide moiety,(2013) 373–383; DOI: 10.1016/j.ejmech.2013.08.048.
    Open DOISearch in Google Scholar
  21. 21. M. M. Ghorab and M. S. Alsaid, Synthesis and antitumor activity of some novel hydrazide, 1, 2-dihydropyridine, chromene, and benzochromene derivatives,(2012) 272–280; DOI: 10.1002/jhet.829.
    Open DOISearch in Google Scholar
  22. 22. M. M. Ghorab, F. A. Ragab, H. I. Hieba and W. M. Ghorab, Design and synthesis of some novel quinoline derivatives as anticancer and radiosensitizing agents targeting VEGFR tyrosine kinase,(2011) 1269–1279; DOI: 10.1002/jhet.749.
    Open DOISearch in Google Scholar
  23. 23. M. M. Ghorab, M. S. Alsaid and E.M. El-hossary, In vitro cytotoxic evaluation of some new heterocyclic sulfonamide derivatives,(2011) 563–571; DOI: 10.1002/jhet.619.
    Open DOISearch in Google Scholar
  24. 24. H. Cope, R. Mutter, W. Heal, C. Pascoe, P. Brown, S. Pratt and B. Chen, Synthesis and SAR study of acridine, 2-methylquinoline and 2-phenylquinazoline analogues as anti-prion agents,(2006) 1124–1143; DOI: 10.1016/j.ejmech.-2006.05.002.
    Search in Google Scholar
  25. 25. K. Juvale, J. Gallus and M. Wiese, Investigation of quinazolines as inhibitors of breast cancer resistance protein (ABCG2),(2013) 7858–7873; DOI: 10.1016/j.bmc.2013.10.007.
    Open DOISearch in Google Scholar
  26. 26. B. R. Dravyakar and P. B. Khedekar, Study of synthesis of novel,2-diphenylquinazolin-4-amine derivatives as an anti-inflammatory and analgesic agent,(2012) 699–706.
    Search in Google Scholar
  27. 27. J. Kapil and W. Michael, 4-Substituted-2-phenylquinazolines as inhibitors of BCRP,(2012) 6766–6769; DOI: /10.1016/j.bmcl.2012.08.024.
    Open DOISearch in Google Scholar
  28. 28. F. Ebel, A. Schuhmacher and K. E. Kling,, Patent DE 1046565, December 18, 1958.
    Search in Google Scholar
  29. 29. P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. McMahon, D. Vistica, J. T. Warren, H. Bokesch, S. Kenney and M. R. Boyd, New colorimetric cytotoxicity assay for anticancer-drug screening,(1990) 1107–1112; DOI: 10.1093/jnci/-82.13.1107.
    Search in Google Scholar
DOI: https://doi.org/10.1515/acph-2015-0021 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
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Language: English
Page range: 299 - 309
Accepted on: Feb 16, 2015
Published on: Sep 30, 2015
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Keywords:
4-aminoquinazoline derivatives,
synthesis,
anti-breast cancer activity
Related subjects:
Pharmacy,
Pharmacy, other

© 2015 Mostafa M. Ghorab, Mansour S. Alsaid, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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