References
- 1. S. B. Mhaske and N. P. Argade, The chemistry of recently isolated naturally occurring quinazolinone alkaloids, Tetrahedron62 (2006) 9787–9826; DOI: 10.1016/j.tet.2006.07.098.
- 2. N. J. Liverton, D. J. Armstrong, D. A. Claremon, D. C. Remy, J. J. Baldwin, R. J. Lynch, G. Zhang and R. J. Gould, Nonpeptide glycoprotein IIb/IIIa inhibitors: Substituted quinazolinediones and quinazolinones as potent fibrinogen receptor antagonists, Bioorg. Med. Chem. Lett. 8 (1998) 483–486; DOI: 10.1016/S0960-894X(98)00047-X.
- 3. W. Zhang, J. P. Mayer, S. E. Hall and J. A. Weigel, A polymer-bound iminophosphorane approach for the synthesis of quinolones, J. Comb. Chem.3 (2001) 255–256; DOI: 10.1021/cc000113e.
- 4. R. J. Griffin, S. Srinivasan, K. Bowman, A. H. Calvert, N. J. Curtin, D. R. Newell, L. C. Pemberton and B. T. Golding, Resistance-modifying agents. 5. Synthesis and biological properties of quinazolinone inhibitors of the DNA repair enzyme poly (ADP-ribose) polymerase (PARP), J. Med. Chem.41 (1998) 5247–5256; DOI: 10.1021/jm980273t.
- 5. A. N. Hughes, I. Rafi, M. J. Griffin, H. A. Calvert, D. R. Newell, J. A. Calvrte, A. Johnston, N. Clendeninn and A. V. Boddy, Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days, Clin. Cancer Res.5 (1999) 111–118.
- 6. E. Hamel, C. M. Lin, J. Plowman, H. K. Wang, K. H. Lee and K. D. Paull, Antitumor 2,3-dihydro-2-(aryl)-4(1H)-quinazolinone derivatives: Interactions with tubulin, Biochem. Pharmacol. 51 (1996) 53–59; DOI: 10.1016/0006-2952(95)02156-6.
- 7. S. H. Hwang, A. Rait, K. F. Pirollo, Q. Zhou, V. M. Yenugonda, G. M. Chinigo, M. L. Brown and E. H. Chang, Tumor-targeting nanodelivery enhances the anticancer activity of a novel quinazolinone analogue, Mol. Cancer Ther.7 (2008) 559–568; DOI: 10.1158/1535-7163.MCT-07-0548.
- 8. S. K. Kundu, M. P. D. Mahindaratne, M. V. Quintero, A. Bao and G. R. Negrete, One-pot reductive cyclization to antitumor quinazoline precursors, Arkivoc 2008 (2) 33–42.
- 9. M. H. Cohen, J. R. Johnson, Y. F. Chen, R. Sridhara and R. Pazdur, FDA drug approval summary: Erlotinib (Tarceva®) tablets, Oncologist10 (2005) 461–466; DOI: 10.1634/theoncologist.10-7-461.
- 10. K. Abouzid and S. Shouman, Design, synthesis and in vitro antitumor activity of 4-aminoquino-line and 4-aminoquinazoline derivatives targeting EGFR tyrosine kinase, Bioorg. Med. Chem. 16 (2008) 7543–7551; DOI: 10.1016/j.bmc.2008.07.038.
- 11. A. Witt and J. Bergman, Recent developments in the field of quinazoline chemistry, Curr. Org. Chem. 7 (2003) 659–677; DOI: /10.2174/1385272033486738.
- 12. H. Wong and A. Gansan, Total synthesis of the fumiquinazoline alkaloids: Solution-phase studies, J. Org. Chem. 65 (2003) 1022–1039; DOI: /10.1021/jo9914364.
- 13. J. P. Micheal, Quinoline, quinazoline and acridone alkaloids, Nat. Prod. Rep. 18 (2003) 543–559.
- 14. M. M. Ghorab, M. S. Alsaid and R. K. Arafa, Design, synthesis and potential anti-proliferative activity of some novel 4-aminoquinoline derivatives, Acta Pharm.64 (2014) 285–297; DOI: 10.2478/acph-2014-0030.
- 15. M. M. Ghorab, F. A. Ragab, S. I. Alqasoumi, A. M. Alafeefy and S. A. Aboulmagd, Synthesis of some new pyrazolo [3, 4-d] pyrimidine derivatives of expected anticancer and radioprotective activity, Eur. J. Med. Chem.45 (2010) 171–178; DOI: 10.1016/j.bmc.–2013.11.042.
- 16. M. M. Ghorab, H. I. Zienab, A. Mohamad and A. A. Radwan, Synthesis, antimicrobial evaluation and molecular modelling of novel sulfonamides carrying a biologically active quinazoline nucleus, J. Pharm. Res.36 (2013) 660–670; DOI: 10.1007/s12272-013-0094-6.
- 17. M. M. Ghorab, H. I. Zienab, A. A. Radwan and A. Mohamad, Synthesis and pharmacophore modeling of novel quinazolines bearing a biologically active sulfonamide moiety, Acta Pharm. 63 (2013) 1–18; DOI: 10.2478/acph-2013-0006.
- 18. M. M. Ghorab, F. A. Ragab, H. I Heiba and M. G. El-Gazzar, Synthesis, in vitro anticancer screening and radiosensitizing evaluation of some new 4-[3-(substituted)thioureido]-N-(quinoxalin-2-yl)-benzenesulfonamide derivatives, Acta Pharm.61 (2011) 415–425; DOI: 10.2478/v10007-011-0040-4.
- 19. M. M. Ghorab, F. A. Ragab, H. I. Hieba, H. A. Yousef and M. G. El-Gazzar, Synthesis of novel pyrazole and pyrimidine derivatives bearing sulfonamide moiety as antitumor and radiosensitizing agents, Med. Chem. Res.21 (2012) 1376–1383; DOI: 10.1007/s00044-013-0721-2
- 20. M. S. Al-Dosari, M. M. Ghorab, M. S. Alsaid, Y. M. Nissan and A. B. Ahmed, Synthesis and anti-cancer activity of some novel trifluoromethylquinolines carrying a biologically active benzene-sulfonamide moiety, Eur. J. Med. Chem.69 (2013) 373–383; DOI: 10.1016/j.ejmech.2013.08.048.
- 21. M. M. Ghorab and M. S. Alsaid, Synthesis and antitumor activity of some novel hydrazide, 1, 2-dihydropyridine, chromene, and benzochromene derivatives, J. Heterocycl. Chem.49 (2012) 272–280; DOI: 10.1002/jhet.829.
- 22. M. M. Ghorab, F. A. Ragab, H. I. Hieba and W. M. Ghorab, Design and synthesis of some novel quinoline derivatives as anticancer and radiosensitizing agents targeting VEGFR tyrosine kinase, J. Heterocycl. Chem.48 (2011) 1269–1279; DOI: 10.1002/jhet.749.
- 23. M. M. Ghorab, M. S. Alsaid and E.M. El-hossary, In vitro cytotoxic evaluation of some new heterocyclic sulfonamide derivatives, J. Heterocycl. Chem.48 (2011) 563–571; DOI: 10.1002/jhet.619.
- 24. H. Cope, R. Mutter, W. Heal, C. Pascoe, P. Brown, S. Pratt and B. Chen, Synthesis and SAR study of acridine, 2-methylquinoline and 2-phenylquinazoline analogues as anti-prion agents, Eur. J. Med. Chem.41 (2006) 1124–1143; DOI: 10.1016/j.ejmech.-2006.05.002.
- 25. K. Juvale, J. Gallus and M. Wiese, Investigation of quinazolines as inhibitors of breast cancer resistance protein (ABCG2), Bioorg. Med. Chem.21 (2013) 7858–7873; DOI: 10.1016/j.bmc.2013.10.007.
- 26. B. R. Dravyakar and P. B. Khedekar, Study of synthesis of novel N,2-diphenylquinazolin-4-amine derivatives as an anti-inflammatory and analgesic agent, Der Pharma Chem.4 (2012) 699–706.
- 27. J. Kapil and W. Michael, 4-Substituted-2-phenylquinazolines as inhibitors of BCRP, Bioorg. Med. Chem. Lett.22 (2012) 6766–6769; DOI: /10.1016/j.bmcl.2012.08.024.
- 28. F. Ebel, A. Schuhmacher and K. E. Kling, Vat Dyes for Dyeing Fibers, Fabrics, and Other Structures Consisting of High Molecular Weight Substances Containing Carboxamide Groups, Patent DE 1046565, December 18, 1958.
- 29. P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. McMahon, D. Vistica, J. T. Warren, H. Bokesch, S. Kenney and M. R. Boyd, New colorimetric cytotoxicity assay for anticancer-drug screening, J. Natl. Cancer Inst.82 (1990) 1107–1112; DOI: 10.1093/jnci/-82.13.1107.