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Epidermal growth factor receptor variants in patients from Myanmar with lung adenocarcinoma Cover

Epidermal growth factor receptor variants in patients from Myanmar with lung adenocarcinoma

Open Access
|Aug 2020

Figures & Tables

Figure 1

Immunoreactivity for a panel of antibodies in various lung carcinoma. The panel included antibodies to thyroid transcription factor-1 (TTF1; orange), P40 (yellow), synaptophysin (green), napsin A (blue), and cytokeratin-7 (CK7; brown). Ab, antibody; CA, carcinoma.
Immunoreactivity for a panel of antibodies in various lung carcinoma. The panel included antibodies to thyroid transcription factor-1 (TTF1; orange), P40 (yellow), synaptophysin (green), napsin A (blue), and cytokeratin-7 (CK7; brown). Ab, antibody; CA, carcinoma.

Figure 2

Frequency of epidermal growth factor receptor sequence variation types by sex in 40 cases of confirmed adenocarcinoma of the lung. Female patients (light gray) male patients (dark gray).
Frequency of epidermal growth factor receptor sequence variation types by sex in 40 cases of confirmed adenocarcinoma of the lung. Female patients (light gray) male patients (dark gray).

Association between EGFR variation and clinical features

CharacteristicTotalEGFR variationP
Detected (%)Not detected (%)
Family cancer history
Present72 (29%)5 (71%)0.69
Absent3313 (39%)20 (61%)
Age group
<40 years11 (100%)0 (0%)0.35
40–59 years115 (45%)6 (55%)
≥60 years289 (32%)19 (68%)
Sex
Male195 (26%)14 (74%)0.17
Female2110 (48%)11 (52%)
Ethnicity
Bamar3815 (39%)23 (61%)0.52
Kayin20 (0.0%)2 (100%)
Occupation
Unemployed189 (50%)9 (50%)0.60
Service and sale workers71 (14%)6 (86%)
Officers/managers51 (20%)4 (80%)
Professionals31 (33%)2 (67%)
Armed forces occupations32 (67%)1 (33%)
Technicians10 (0%)1 (100%)
Transporters21 (50%)1 (50%)
Agricultural, forestry, and fishery workers10 (0%)1 (100%)
Smoking habit
Regular smokers40 (0%)4 (100%)0.008*
Ex-smokers215 (24%)16 (76%)
Never-smokers1510 (67%)5 (33%)
Chemical/dust exposure
Exposure present91 (11%)8 (89%)0.12
No exposure3114 (45%)17 (55%)
DOI: https://doi.org/10.1515/abm-2020-0011 | Journal eISSN: 1875-855X | Journal ISSN: 1905-7415
Language: English
Page range: 75 - 81
Published on: Aug 4, 2020
Published by: Chulalongkorn University
In partnership with: Paradigm Publishing Services
Publication frequency: 6 issues per year

© 2020 Khine San Yin, Myint Myint Naing, Nitar Khine, May Phyo Maung, Aye Aye Nyunt, Nway Nway Htike, Hnin Hnin Aye, Aye Aye Myint, published by Chulalongkorn University
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.