Plasma GLP-1 and GIP levels in patients in the control group and in patients with hypothyroidism before treatment and hypothyroidism after treatment
| Laboratory parameters | Control (n = 13) | Hypothyroidism before treatment (n = 13) | Hypothyroidism after treatment (n = 13) | P (control vs hypothyroidism before treatment) | P (hypothyroidism before vs after treatment) |
|---|---|---|---|---|---|
| GLP-1 levels (pg/ml) | |||||
| Baseline | 3.88 ± 1.54 | 3.90 ± 1.47 | 4.12 ± 1.64 | 0.93 | 0.67 |
| 30th min | 5.63 ± 1.74 | 5.58 ± 1.93 | 6.01 ± 2.40 | 0.83 | 0.51 |
| 60th min | 4.9 ± 1.7 | 5.0 ± 2.1 | 5.16 ± 2.09 | 0.74 | 0.59 |
| 90th min | 4.47 ± 1.73 | 5.67 ± 1.85 | 5.53 ± 2.21 | 0.17 | 0.64 |
| 120th min | 3.87 ± 1.52 | 4.50 ± 1.01 | 5.04 ± 2.15 | 0.29 | 0.15 |
| GIP levels (pg/ml) | |||||
| Baseline | 44.5 ± 28.9 | 55.1 ± 18.7 | 53.4 ± 15.3 | 0.59 | 0.74 |
| 30th min | 81.1 ± 31.9 | 69.1 ± 22.6 | 87.1 ± 21.9 | 0.89 | 0.19 |
| 60th min | 85.9 ± 47.0 | 79.1 ± 32.7 | 83.6 ± 20.1 | 0.94 | 0.14 |
| 90th min | 96.5 ± 42.7 | 75.8 ± 26.4 | 74.2 ± 16.5 | 0.38 | 0.62 |
| 120th min | 64.5 ± 32.9 | 68.4 ± 33.1 | 58.0 ± 13.8 | 0.56 | 0.54 |
Plasma glucose and insulin levels in patients in the control group and in patients with hypothyroidism before treatment and hypothyroidism after treatmentResults are shown as mean ± standard deviation for normal distribution and median (minimum–maximum) for abnormal distribution_
| Laboratory parameters | Control (n = 13) | Hypothyroidism before treatment (n = 13) | Hypothyroidism after treatment (n = 13) | P (control vs hypothyroidism before treatment) | P (hypothyroidism before vs after treatment) |
|---|---|---|---|---|---|
| Glucose levels (mg/dl) | |||||
| Baseline | 87.46 ± 6.85 | 90.30 ± 3.85 | 90.38 ± 7.24 | 0.143 | 0.972 |
| 30th min | 141.65 ± 40.72 | 145.92 ± 22.38 | 148.15 ± 26.84 | 0.343 | 0.753 |
| 60th min | 139.47 ± 45.79 | 142.84 ± 27.09 | 128.30 ± 28.31 | 0.663 | 0.05 |
| 90th min | 117.01 ± 25.34 | 121.69 ± 34.48 | 118.61 ± 30.84 | 0.939 | 0.610 |
| 120th min | 96.60 ± 30.78 | 104.92 ± 31.67 | 102.89 ± 29.95 | 0.555 | 0.272 |
| Insulin levels (mU/ml) | |||||
| Baseline | 10.32 ± 4.79 | 8.24 ± 3.31 | 9.66 ± 4.51 | 0.191 | 0.152 |
| 30th min | 54.74 (22.99– | 54.14 (23.7–229.6) | 56.35 (34.06–243.9) | 0.858 | 0.422 |
| 294.3) | |||||
| 60th min | 56.32 (18.53– | 69.95 (23.87–160.7) | 53.43 (28.7–146.7) | 0.59 | 0.116 |
| 90th min | 226.6) 46.7 (7.9–121.8) | 42.75 (8.1–127.1) | 42.94 (9.36–208.5) | 0.957 | 0.753 |
| 120th min | 27.65 (4.87– | 32.08 (7.61–18) | 31.34 (6.26–133.5) | 0.317 | 0.249 |
| 132.7) | |||||