Demographics and perioperative data of patients undergoing pancreaticoduodenectomy
| All patients | Group 1 | Group 2 | P | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Range | Mean | Median | Range | Mean | Median | Range | Mean | Median | ||
| Age (years) | 33–89 | 62.9 ± 12.7 | 63.5 | 36–78 | 59.7 ± 11.0 | 62 | 33–89 | 65.9 ± 13.5 | 67 | NS |
| Presenting serum bilirubin (mg%) | 5.5–52.7 | 21.4 ± 11.5 | 20.6 | 8.7–52.0 | 24.4 ± 12.2 | 21.2 | 5.5–52.7 | 19.3 ± 10.5 | 20.3 | NS |
| Duration of jaundice (days) | 7–120 | 38.5 ± 34.0 | 30 | 7–120 | 52.5 ± 43.1 | 42 | 8–60 | 26.1 ± 14.5 | 30 | 0.0035 |
| Operative time (minute) | 300–780 | 420.6 ± 82.8 | 420 | 300–780 | 423.5 ± 96.8 | 420 | 300–540 | 417.9 ± 67.1 | 420 | NS |
| Operative blood transfusion (unit) | 0–7 | 2.7 ± 1.7 | 3 | 0–7 | 2.8 ± 2.0 | 3 | 0–5 | 2.6 ± 1.4 | 2.5 | NS |
| Hospital stay (days) | 12–106 | 28.9 ± 17.8 | 22.5 | 12–106 | 31.8 ± 23.3 | 23.5 | 15–45 | 26.1 ± 9.5 | 21 | NS |
Pathological diagnosis of the periampullary lesions
| Pathological diagnosis | All patients | Group 1 | Group 2 | P |
|---|---|---|---|---|
| Carcinoma of the head of the pancreas | 23 | 10 | 13 | NS |
| Carcinoma of the ampulla of Vater | 20 | 14 | 6 | 0.029 |
| Carcinoma of the distal common bile duct | 5 | 0 | 5 | NS |
| Chronic pancreatitis | 2 | 0 | 2 | NS |
| Carcinoma of the duodenum | 1 | 0 | 1 | NS |
| Acute pancreatitis | 1 | 1 | 0 | NS |
| Sarcoma of the pancreatic head | 1 | 0 | 1 | NS |
| Neuroendocrine tumor of the pancreas | 1 | 1 | 0 | NS |
| Total | 54 | 26 | 28 |
Cholangitis at presentation and operative procedure (classical PD or PPPD)
| Group 1 (n = 26) | Group 2 (n = 28) | P | |
|---|---|---|---|
| PPPD | 20 | 26 | NS |
| Classical PD | 6 | 2 | NS |
| Cholangitis | 11 | 0 | < 0.0001 |
| No cholangitis | 15 | 28 | NS |
Postoperative complications
| Complication | Group 1 | Group 2 | P |
|---|---|---|---|
| Wound infection | 3 | 3 | NS |
| Grade A pancreatic fistula | 5 | 1 | NS |
| Early delayed gastric emptying | 2 | 2 | NS |
| Intraabdominal bleeding | 2 | 1 | NS |
| Intraabdominal collection | 5 | 1 | NS |
| Congestive heart failure | 0 | 1 | NS |
| Overall complications | 17 | 9 | 0.03 |